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Protein Overview: CycC-PA

General Information:
Name(s) found: CycC-PA / FBpp0082469 [FlyBase]
Description(s) found:
Found 26 descriptions.
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  • The gene Cyclin C is referred to in FlyBase by the symbol Dmel\CycC (CG7281, FBgn0004597). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:10714726..10715915. It has the cytological map location 88D6. There is experimental evidence that it has the molecular function</span>: protein binding; RNA polymerase II transcription mediator activity; cyclin-dependent protein kinase regulator activity. There is experimental evidence that it is involved in the biological process</span>: regulation of transcription from RNA polymerase II promoter. 6 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 267 amino acids

    Gene Ontology:
    Cellular Component: nuclear cyclin-dependent protein kinase holoenzyme complex [NAS]
    mediator complex [IDA][ISS]
    Biological Process: G1/S transition of mitotic cell cycle [NAS]
    transcription initiation from RNA polymerase II promoter [ISS]
    regulation of transcription from RNA polymerase II promoter [IMP]
    Molecular Function: cyclin-dependent protein kinase regulator activity [IDA][ISS][NAS]
    protein binding [IPI]
    RNA polymerase II transcription mediator activity [IMP][ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAGNFWQSSH SQQWILDKPD LLRERQHDLL ALNEDEYQKV FIFFANVIQV LGEQLKLRQQ  60
   61 VIATATVYFK RFYARNSLKN IDPLLLAPTC ILLASKVEEF GVISNSRLIS ICQSAIKTKF 120
  121 SYAYAQEFPY RTNHILECEF YLLENLDCCL IVYQPYRPLL QLVQDMGQED QLLTLSWRIV 180
  181 NDSLRTDVCL LYPPYQIAIA CLQIACVILQ KDATKQWFAE LNVDLDKVQE IVRAIVNLYE 240
  241 LWKDWKEKDE IQMLLSKIPK PKPPPQR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..267] PSI-BLAST 55.69897 No description for 2b9rA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle