Protein Overview: FBpp0301708, su(...

General Information:
Name(s) found:	FBpp0301708 [FlyBase] su(Hw)-PA / FBpp0082405 [FlyBase] su(Hw)-PB / FBpp0082404 [FlyBase]
Description(s) found: Found 44 descriptions. SHOW ALL	type=protein; loc=3R:complement(10130530..10131620,10131682..10131806,10131875..10132065,10132136..10132268,10132326..10132753,10132820..10133677); ID=FBpp0301708; name=su(Hw)-PC; parent=FBgn0003567,FBtr0310002; dbxref=FlyBase:FBpp0301708,FlyBase_Annotation_IDs:CG8573-PC,REFSEQ:NP_001247098,GB_protein:AFH06416; MD5=a6d3f9d3eb99435a4d462bd7ffc8e622; length=941; release=r5.56; species=Dmel; [FlyBase] The gene suppressor of Hairy wing is referred to in FlyBase by the symbol Dmel\su(Hw) (CG8573, FBgn0003567). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:10130177..10134309. It has the cytological map location 88B3. There is experimental evidence that it has the molecular function</span>: protein binding; transcription regulator activity; transcription repressor activity; DNA binding; chromatin insulator sequence binding. There is experimental evidence that it is involved in the biological process</span>: negative regulation of chromatin silencing; negative regulation of transcription; negative regulation of transcription, DNA-dependent. 53 alleles are reported. The phenotypes of these alleles are annotated with: cuticle; egg chamber. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase] The gene suppressor of Hairy wing is referred to in FlyBase by the symbol Dmel\su(Hw) (CG8573, FBgn0003567). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:10130177..10134309. It has the cytological map location 88B3. There is experimental evidence that it has the molecular function</span>: protein binding; transcription regulator activity; transcription repressor activity; DNA binding; chromatin insulator sequence binding. There is experimental evidence that it is involved in the biological process</span>: negative regulation of chromatin silencing; negative regulation of transcription; negative regulation of transcription, DNA-dependent. 53 alleles are reported. The phenotypes of these alleles are annotated with: cuticle; egg chamber. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	941 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA][ISS][NAS] chromatin [IDA]
Biological Process:	negative regulation of transcription, DNA-dependent [IMP] negative regulation of transcription [IMP] negative regulation of chromatin silencing [IMP]
Molecular Function:	DNA binding [IMP][NAS] zinc ion binding [IEA] protein binding [IPI] transcription regulator activity [IMP] chromatin insulator sequence binding [IDA] transcription repressor activity [IMP]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSASKEGKEK KGKLLGVENI SPPKDKRPAT RMKLLNDVGA GEDSEASTTT TTSRTPSNKQ  60
   61 EKRGSVAGSR IKILNEEILG TPKTEKRGAT KSTAPAASTV KILNEKKTPS ATVTAVETTK 120
  121 IKTSPSKRKK MEHYVLQAVK SENTKADTTV TVVTEEDDTI DFILADDEEV VPGRIENNNG 180
  181 QEIVVTEDDE DLGEDGDEDG EDSSGKGNSS QTKIKEIVEH VCGKCYKTFR RVQSLKKHLE 240
  241 FCRYDSGYHL RKADMLKNLE KIEKDAVVME KKDICFCCSE SYDTFHLGHI NCPDCPKSFK 300
  301 TQTSYERHIF ITHSEFSDFP CSICNANLRS EALLALHEEQ HKSRGKPYAC KICGKDFTRS 360
  361 YHLKRHQKYS SCSSNETDTM SCKVCDRVFY RLDNLRSHLK QHLGTQVVKK PEYMCHTCKN 420
  421 CFYSLSTLNI HIRTHTGEKP FDCDLCDKKF SALVALKKHR RYHTGEKPYS CTVCNQAFAV 480
  481 KEVLNRHMKR HTGERPHKCD ECGKSFIQAT QLRTHSKTHI RPFPCEQCDE KFKTEKQLER 540
  541 HVKTHSRTKR PVFSCAECKR NFRTPALLKE HMDEGKHSPK QQRSSMRSAV KIMERTDCAI 600
  601 CDKNFDSSDT LRRHIRTVHE CDPDDIFGVE PHPSKRAKKD IESEEVVPVA LNTSAGSLIS 660
  661 SQTDGNGVVV REFLVDEGDG AAQTITLENE TYTILPLDGA IEGEQLTDEA GVKPEAKKEE 720
  721 AQVSPVVKKE QRKSLAASLA AAIADNLEES CSEDDFSGEI LTEEDIKLKE NVGKLIDMLV 780
  781 DPPILKKYGW PNAPEETVLC KVIENCGHDL TKGGENYAEL DYGSRMREYC KLLFTVVIHN 840
  841 DSIKSLLNNF PIDDVIEYVL GDEDQDEGGL DKDNESHSGD EEAVSVTGET KTNEIREKPE 900
  901 KKEVSAKSEK KEIVGKAVDK DNSEEVVREN KKKPVGEQEK A

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: FBpp0301708, su(...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: