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Protein Overview: Vha55-PC, Vha55-...

General Information:
Name(s) found: Vha55-PC / FBpp0290875 [FlyBase]
Vha55-PA / FBpp0082140 [FlyBase]
Vha55-PB / FBpp0082139 [FlyBase]
Description(s) found:
Found 51 descriptions.
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  • The gene Vacuolar H<sup>+</sup>-ATPase 55kD B subunit is referred to in FlyBase by the symbol Dmel\Vha55 (CG17369, FBgn0005671). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:8449484..8453551. It has the cytological map location 87C2-87C3. Based on sequence similarity, it is predicted to have molecular function</span>: hydrogen-exporting ATPase activity, phosphorylative mechanism. It is reported to be involved in the biological process</span>: proton transport. 21 alleles are reported. The phenotype of these alleles is annotated with: Malpighian tubule. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
  • The gene Vacuolar H<sup>+</sup>-ATPase 55kD B subunit is referred to in FlyBase by the symbol Dmel\Vha55 (CG17369, FBgn0005671). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:8449484..8453551. It has the cytological map location 87C2-87C3. Based on sequence similarity, it is predicted to have molecular function</span>: hydrogen-exporting ATPase activity, phosphorylative mechanism. It is reported to be involved in the biological process</span>: proton transport. 21 alleles are reported. The phenotype of these alleles is annotated with: Malpighian tubule. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
  • The gene Vacuolar H<sup>+</sup>-ATPase 55kD B subunit is referred to in FlyBase by the symbol Dmel\Vha55 (CG17369, FBgn0005671). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:8449484..8453551. It has the cytological map location 87C2-87C3. Based on sequence similarity, it is predicted to have molecular function</span>: hydrogen-exporting ATPase activity, phosphorylative mechanism. It is reported to be involved in the biological process</span>: proton transport. 21 alleles are reported. The phenotype of these alleles is annotated with: Malpighian tubule. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 490 amino acids

    Gene Ontology:
    Cellular Component: vacuolar proton-transporting V-type ATPase, V1 domain [ISS][NAS]
    Biological Process: proton transport [NAS]
    ATP synthesis coupled proton transport [IEA]
    Molecular Function: hydrogen-exporting ATPase activity, phosphorylative mechanism [ISS][NAS]
    proton-transporting ATPase activity, rotational mechanism [IEA]
    hydrogen ion transporting ATP synthase activity, rotational mechanism [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNAQQAQREH VLAVSRDFIS QPRLTYKTVS GVNGPLVILD EVKFPKFAEI VQLRLADGTV  60
   61 RSGQVLEVSG SKAVVQVFEG TSGIDAKNTL CEFTGDILRT PVSEDMLGRV FNGSGKPIDK 120
  121 GPPILAEDFL DIQGQPINPW SRIYPEEMIQ TGISAIDVMN SIARGQKIPI FSAAGLPHNE 180
  181 IAAQICRQAG LVKLPGKSVL DDHTDNFAIV FAAMGVNMET ARFFKQDFEE NGSMENVCLF 240
  241 LNLANDPTIE RIITPRLALT AAEFLAYQCE KHVLVILTDM SSYAEALREV SAAREEVPGR 300
  301 RGFPGYMYTD LATIYERAGR VEGRNGSITQ IPILTMPNDD ITHPIPDLTG YITEGQIYVD 360
  361 RQLHNRQIYP PVNVLPSLSR LMKSAIGEGM TRKDHSDVSN QLYACYAIGK DVQAMKAVVG 420
  421 EEALTPDDLL YLEFLTKFEK NFISQGNYEN RTVFESLDIG WQLLRIFPKE MLKRIPASIL 480
  481 AEFYPRDSRH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..490] PSI-BLAST 108.0 No description for 2c61A was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle