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Protein Overview: CoVa-PB, FBpp030...

General Information:
Name(s) found: FBpp0306911 [FlyBase]
CoVa-PB / FBpp0081948 [FlyBase]
CoVa-PA / FBpp0081947 [FlyBase]
Description(s) found:
Found 46 descriptions.
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  • type=protein; loc=3R:7645434..7645883; ID=FBpp0306911; name=CoVa-PC; parent=FBgn0019624,FBtr0334890; dbxref=FlyBase:FBpp0306911,FlyBase_Annotation_IDs:CG14724-PC,REFSEQ:NP_001262488,GB_protein:AGB95870; MD5=a25949953d866713f855cbc0e2311491; length=149; release=r5.56; species=Dmel; [FlyBase]
  • The gene Cytochrome c oxidase subunit Va is referred to in FlyBase by the symbol Dmel\CoVa (CG14724, FBgn0019624). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:7645081..7646021. It has the cytological map location 86F9. Based on sequence similarity, it is predicted to have molecular function</span>: cytochrome-c oxidase activity. There is experimental evidence that it is involved in the biological process</span>: positive regulation of cell cycle. 5 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • The gene Cytochrome c oxidase subunit Va is referred to in FlyBase by the symbol Dmel\CoVa (CG14724, FBgn0019624). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:7645081..7646021. It has the cytological map location 86F9. Based on sequence similarity, it is predicted to have molecular function</span>: cytochrome-c oxidase activity. There is experimental evidence that it is involved in the biological process</span>: positive regulation of cell cycle. 5 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 149 amino acids

    Gene Ontology:
    Cellular Component: lipid particle [IDA]
    mitochondrial respiratory chain complex IV [ISS][NAS]
    mitochondrial inner membrane [NAS]
    Biological Process: mitochondrial electron transport, cytochrome c to oxygen [ISS]
    positive regulation of cell cycle [IMP]
    Molecular Function: cytochrome-c oxidase activity [ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLSITARNLA SALRSSLVGT SSRVAAVRCL HGTEESAEEF DKRYEKYFSR EGIDGWEIRK  60
   61 GMNDLLGMDL VPSPKIIEAG LRASRRVNDI ALAIRWLEGC KDKCGDQKAT LYPYLLEKIT 120
  121 PTLQELGIPT IEELGYDKPE LALKSVYDA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..149] PSI-BLAST 54.0 Cytochrome c oxidase subunit E

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • cytochrome-c oxidase activity
    		•  13.5907467824992 bayes_pls_golite062009
  • oxidoreductase activity, acting on heme group of donors
    		•  13.5907467824992 bayes_pls_golite062009
  • oxidoreductase activity, acting on heme group of donors, oxygen as acceptor
    		•  13.5907467824992 bayes_pls_golite062009
  • heme-copper terminal oxidase activity
    		•  13.2768834037467 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  7.11269745957917 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  6.95782581983891 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  6.3444074949287 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  6.0779545597528 bayes_pls_golite062009
  • oxidoreductase activity
    		•  6.07124287051458 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  5.87041225771312 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  5.44223516926039 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  5.2274118132466 bayes_pls_golite062009
  • electron carrier activity
    		•  1.73787331766336 bayes_pls_golite062009
  • catalytic activity
    		•  1.17990683373825 bayes_pls_golite062009
  • transporter activity
    		•  0.0449232084165001 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.0241192035901199 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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