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Protein Overview: glo-PA, glo-PB

General Information:
Name(s) found: glo-PA / FBpp0088858 [FlyBase]
glo-PB / FBpp0088856 [FlyBase]
Description(s) found:
Found 36 descriptions.
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  • The gene glorund is referred to in FlyBase by the symbol Dmel\glo (CG6946, FBgn0259139). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:7640928..7645142. It has the cytological map location 86F8-86F9. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: regulation of translation; intracellular mRNA localization involved in pattern specification process; pole plasm oskar mRNA localization; maternal specification of dorsal/ventral axis, oocyte, germ-line encoded; chromosome organization; oogenesis. 10 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
  • The gene glorund is referred to in FlyBase by the symbol Dmel\glo (CG6946, FBgn0259139). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:7640928..7645142. It has the cytological map location 86F8-86F9. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: regulation of translation; intracellular mRNA localization involved in pattern specification process; pole plasm oskar mRNA localization; maternal specification of dorsal/ventral axis, oocyte, germ-line encoded; chromosome organization; oogenesis. 10 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 586 amino acids

    Gene Ontology:
    Cellular Component: protein complex [IPI]
    Biological Process: regulation of translation [IMP][NAS]
    oogenesis [IMP]
    chromosome organization [IMP]
    pole plasm oskar mRNA localization [IMP]
    maternal specification of dorsal/ventral axis, oocyte, germ-line encoded [IMP]
    intracellular mRNA localization involved in pattern specification process [IMP]
    Molecular Function: nucleotide binding [IEA]
    nucleic acid binding [IEA]
    protein binding [IPI]
    mRNA binding [ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNADVQFNY GQQGNGDNFN DDSNQQQDED DQYNEDGGGK IENVGESPKF VRLRGLPWSA  60
   61 THKEILDFLE NVNVTNGSAG IHLVTSRVDG KNTGEAYVEV ASQEDVEEAR KLNKASMGHR 120
  121 YIEVFTATPK EAKEAMRKIS GHGTAFVVKL RGLPYAVTEQ QIEEFFSGLD IKTDREGILF 180
  181 VMDRRGRATG EAFVQFESQD DTEQALGRNR EKIGHRYIEI FRSSIAEMKR ATGAGGGVGG 240
  241 RPGPYDIRDR GANRGGNDFG GGRNDWGNNG NFGVGANNML GFNNLPSLMN SGNFGNNQGG 300
  301 NNGNFGNNSG PSNFGNFGGG NNGGNSGNFG NDSGNSGNFG NFGNNGGGNF GGNNNGGGGF 360
  361 NSGNNFNSPG GVNNFGNNGG SNFGGNGGGG FNNGGNFVSS SGVGNFGPIG GGRNNNNGNF 420
  421 GNSGFGNFGG NNNVGSNFGG GNNGGGGGFN NGSNFGGGNS MGGGGNFGPI GGGRGNDIEY 480
  481 YTIHMRGLPY TSFENDVFKF FEPIRPANVR INYNKKGLHS GTADAYFDTY EDSQVAMKRH 540
  541 REQMGSRYIE LFYDGKTRGL NGGEHGGGNG GGGMGNNGGG NFSRRI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..235] PSI-BLAST 53.522879 UP1, THE TWO RNA-RECOGNITION MOTIF DOMAIN OF HNRNP A1
    2 View Details [236..449] deduced N/A No confident structure predictions are available.
    3 View Details [450..586] PSI-BLAST 12.69897 No description for 2hgnA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  0.950788308762215 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.29562225149076 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle