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Protein Overview: PGRP-LB-PC

General Information:
Name(s) found: PGRP-LB-PC / FBpp0081872 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • The gene Peptidoglycan recognition protein LB is referred to in FlyBase by the symbol Dmel\PGRP-LB (CG14704, FBgn0037906). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:7278563..7283742. It has the cytological map location 86E6. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: defense response to Gram-positive bacterium. 3 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 232 amino acids

    Gene Ontology:
    Cellular Component: integral to plasma membrane [NAS]
    extracellular region [IDA]
    Biological Process: immune response [ISS]
    peptidoglycan catabolic process [IEA]
    peptidoglycan metabolic process [NAS]
    detection of bacterium [NAS]
    defense response [NAS]
    defense response to Gram-positive bacterium [IDA]
    Molecular Function: peptidoglycan binding [ISS][NAS][TAS]
    protein binding [IPI]
    amidase activity [NAS]
    N-acetylmuramoyl-L-alanine amidase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTALGLVLLS MMGYSQHMQQ ANLGDGVATA RLLSRSDWGA RLPKSVEHFQ GPAPYVIIHH  60
   61 SYMPAVCYST PDCMKSMRDM QDFHQLERGW NDIGYSFGIG GDGMIYTGRG FNVIGAHAPK 120
  121 YNDKSVGIVL IGDWRTELPP KQMLDAAKNL IAFGVFKGYI DPAYKLLGHR QVRDTECPGG 180
  181 RLFAEISSWP HFTHINDTEG VSSTTAPVVP HVHPQAAAPQ KPHQSPPAAP KV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..232] PSI-BLAST 51.69897 Peptidoglycan recognition protein-lb (Cg14704)


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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