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Protein Overview: Best1-PA

General Information:
Name(s) found: Best1-PA / FBpp0081661 [FlyBase]
Description(s) found:
Found 26 descriptions.
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  • The gene Bestrophin 1 is referred to in FlyBase by the symbol Dmel\Best1 (CG6264, FBgn0040238). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:5987186..5996207. It has the cytological map location 85F15-85F16. It is reported to have molecular function</span>: chloride channel activity. The biological processes in which it is involved are not known. 15 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 721 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: chloride channel activity [NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTITYTGEVA TCRGFGCFLK LLLRWRGSIY KLVWLDLLAF LTIYYAINMV YRFGLNPAQK  60
   61 ETFEAIVQYC DSYRELIPLS FVLGFYVSIV MTRWWNQYTS IPWPDPIAVF VSSNVHGQDE 120
  121 RGRMMRRTIM RYVCLCLTMV LANVSPRVKK RFPGLNNLVE AGLLNDNEKT IIETMNKAFP 180
  181 RPSKHWLPIV WAASIITRAR KEGRIRDDFA VKTIIDELNK FRGQCGLLIS YDTISVPLVY 240
  241 TQVVTLAVYS YFLTCCMGQQ WTDGKVVGNT TYLNKVDLYF PVFTTLQFFF YMGWLKVAES 300
  301 LINPFGEDDD DFEVNWMVDR NLQVSYLIVD EMHHDHPELL KDQYWDEVFP NELPYTIAAE 360
  361 RFRENHPEPS TAKIEVPKNA AMPSTMSSVR IDEMADDASG IHFSAGNGKM RLDSSPSLVS 420
  421 VSGTLSRVNT VASALKRFLS RDDSRPGSAT PSQDQPYKFP ASASSASLSG AVVGSATSAG 480
  481 KPAGSLRITQ QVIEEVDEQA TITSMRANDP RPNVMDIFAQ TSSGAGTSGP LQPPPAHSEP 540
  541 VDIPSRPPSY NRAQSQYEPN LFPPGGVDAL LSTSAPAGGS PLLLSNAATA PSSPVGESSK 600
  601 SLYDPQKGAS RETVESMDLR SSTDLLGDAA VQPEDEGDDF DKLKAEREKE KLMRQQKNLA 660
  661 RTISTAPGME ATAVPMVPMV PVNVAVQQAQ LQPVASSADL LAGGDQFSNS TMKSEDAING 720
  721 S

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..153] MSA 3.110965 View MSA. No confident structure predictions are available.
    2 View Details [154..340] deduced N/A No confident structure predictions are available.
    3 View Details [341..721] FFAS03 1.28 THE BLUETONGUE VIRUS (BTV) CORE BINDS DSRNA


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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