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Protein Overview: by-PC, by-PA, by-PD

General Information:
Name(s) found: by-PD / FBpp0291577 [FlyBase]
by-PC / FBpp0290315 [FlyBase]
by-PA / FBpp0081597 [FlyBase]
Description(s) found:
Found 36 descriptions.
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  • The gene blistery is referred to in FlyBase by the symbol Dmel\by (CG9379, FBgn0000244). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:5353960..5358734. It has the cytological map location 85D19-85D22. Based on sequence similarity, it is predicted to have molecular function</span>: actin binding. There is experimental evidence that it is involved in the biological process</span>: apposition of dorsal and ventral imaginal disc-derived wing surfaces; imaginal disc-derived wing morphogenesis. 31 alleles are reported. The phenotypes of these alleles are annotated with: dorsal mesothoracic disc; wing; thorax. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
  • The gene blistery is referred to in FlyBase by the symbol Dmel\by (CG9379, FBgn0000244). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:5353960..5358734. It has the cytological map location 85D19-85D22. Based on sequence similarity, it is predicted to have molecular function</span>: actin binding. There is experimental evidence that it is involved in the biological process</span>: apposition of dorsal and ventral imaginal disc-derived wing surfaces; imaginal disc-derived wing morphogenesis. 31 alleles are reported. The phenotypes of these alleles are annotated with: dorsal mesothoracic disc; wing; thorax. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
  • The gene blistery is referred to in FlyBase by the symbol Dmel\by (CG9379, FBgn0000244). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:5353960..5358734. It has the cytological map location 85D19-85D22. Based on sequence similarity, it is predicted to have molecular function</span>: actin binding. There is experimental evidence that it is involved in the biological process</span>: apposition of dorsal and ventral imaginal disc-derived wing surfaces; imaginal disc-derived wing morphogenesis. 31 alleles are reported. The phenotypes of these alleles are annotated with: dorsal mesothoracic disc; wing; thorax. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 720 amino acids

    Gene Ontology:
    Cellular Component: focal adhesion [ISS]
    Biological Process: imaginal disc-derived wing morphogenesis [IMP][NAS]
    apposition of dorsal and ventral imaginal disc-derived wing surfaces [IMP]
    cytoskeletal anchoring at plasma membrane [ISS]
    Molecular Function: actin binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRTPYEESAA AADHKYQYQY TAANNNNNYY KNYNVNGNGQ ANGNGNLSGI GNGNGIGNGN  60
   61 GYGIPYHARE NSLPFSYGIA KTSTPLRKTP TPTRVDSFLD FDFGPTNTNV NSNSSSNNGG 120
  121 TGDMIKPPTR LTSPLLVRKT LGNAVSPTSS TNTNTIANTY HYTSSSATPT PVRDNFEQLL 180
  181 RERREKVYNE YRNLDRESSG ERARVAPAPP QRQYYPSDGY GIGLKNDSNG TLYRKSPSSN 240
  241 GKSTKYNYDF EFNLNLDDVR PEPTPYTTRN IHFEDLRLDQ DVPDGVVNRR TMERNYHTIN 300
  301 SLETTHKRQQ LEPLEQLGAV YGQNHMEETL TRTRRDLSAS TSTSKSTSPL PAIGVPAIAP 360
  361 ASPIYATSTK RVSNPNTNGQ QQMTPSPTSR PETPAFPVTP RTPFGASSSS SASLAPTTQL 420
  421 PPESIYQTGP RRGVPPALQP LEVSADSVQF ARSSSQFWYK PNLTREDAIA LLASAQPGTF 480
  481 LVRDSTTYKD SYGLVVRVSQ PPPGSQELVR HFLIEPTKGG VHLKGCDDEP VFTSLSALVF 540
  541 EHSISQLALP CLLRLPDRDI VPPVRATTPA QQHLLAHGAA TNVLWLYSCD TESLTGNEAI 600
  601 RKAIRQMYGQ QPLPQPTEVH FKVSSQGITL TDNTRKKFFR KHYKADVISH CAIDPENRMW 660
  661 TSEGESDKKT IFAFVARRSH SSTDNQCHVF CDLSVSQPAA AIVSFANRTL PTEKLRNYVL 720
  721

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..108] MSA 6.239996 View MSA. No confident structure predictions are available.
    2 View Details [109..194] deduced N/A No confident structure predictions are available.
    3 View Details [195..306] MSA 5.253989 View MSA. No confident structure predictions are available.
    4 View Details [307..373] deduced N/A No confident structure predictions are available.
    5 View Details [374..446] PSI-BLAST 35.221849 Fyn proto-oncogene tyrosine kinase, SH3 domain; Tyrosine kinase Fyn
    6 View Details [447..664] PSI-BLAST 15.522879 Tyrosine-protein kinase zap-70
    7 View Details [665..720] PSI-BLAST 59.045757 No description for 2gjyA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6
    Term Confidence Notes
  • binding
    		•  2.28887512041698 bayes_pls_golite062009
  • signal transducer activity
    		•  2.07133863841547 bayes_pls_golite062009
  • molecular transducer activity
    		•  2.07133863841547 bayes_pls_golite062009
  • protein binding
    		•  2.04603930248857 bayes_pls_golite062009
  • molecular adaptor activity
    		•  0.93584922485564 bayes_pls_golite062009
  • SH3/SH2 adaptor activity
    		•  0.72842829338771 bayes_pls_golite062009
  • receptor binding
    		•  0.49361386378291 bayes_pls_golite062009
  • protein binding, bridging
    		•  0.192710997278041 bayes_pls_golite062009
    7 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle