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Protein Overview: rump-PA

General Information:
Name(s) found: rump-PA / FBpp0081601 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • The gene rumpelstiltskin is referred to in FlyBase by the symbol Dmel\rump (CG9373, FBgn0260010). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:5331575..5336057. It has the cytological map location 85D18-85D19. There is experimental evidence that it has the molecular function</span>: mRNA binding; mRNA 3'-UTR binding. There is experimental evidence that it is involved in the biological process</span>: intracellular mRNA localization; determination of anterior/posterior axis, embryo. 12 alleles are reported. The phenotype of these alleles is annotated with: embryonic abdominal segment. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 632 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    cytoplasm [IDA]
    Biological Process: intracellular mRNA localization [IMP]
    anterior/posterior axis specification, embryo [IMP]
    Molecular Function: nucleotide binding [IEA]
    mRNA binding [IDA][ISS]
    mRNA 3'-UTR binding [IDA][TAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSMDASNSVE SREKERDRRG RGARGSRFTD ADGNGNGAGS QGGGVAARDR SRERRNCRVY  60
   61 ISNIPYDYRW QDLKDLFRRI VGSIEYVQLF FDESGKARGC GIVEFKDPEN VQKALEKMNR 120
  121 YEVNGRELVV KEDHGEQRDQ YGRIVRDGGG GGGGGGGVQG GNGGNNGGGG GGGRDHMDDR 180
  181 DRGFSRRDDD RLSGRNNFNM MSNDYNNSSN YNLYGLSASF LESLGISGPL HNKVFVANLD 240
  241 YKVDNKKLKQ VFKLAGKVQS VDLSLDKEGN SRGFAVIEYD HPVEAVQAIS MLDRQMLFDR 300
  301 RMTVRLDRIP DKNEGIKLPE GLGGVGIGLG PNGEPLRDVA HNLPNGGQSQ GQLLGNAQQG 360
  361 SQLGSVGSQP NSSAVSNATT NLLNNLTGVM FGNHAAVQPS PVAPVQKPSL GNNTGSGGLN 420
  421 LNNLNPSILA AVVGNLGNQG GNLSNPLLSS SLSNLGLNLG NSGNDDNLPP SNVGLSNNYS 480
  481 SGGTGGGNSY SSGNNYSGGG GSSNLGYNAY SSSGGMGGGN GGVGVDGNDY NTGNPLDVYG 540
  541 GGSNVGNSNV GSANAVGASR KSDTIIIKNV PITCTWQTLR DKFREIGDVK FAEIRGNDVG 600
  601 VVRFFKERDA ELAIALMDGS RLDGRNIKVT YF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..217] FFAS03 3.72 No description for 2ghpA was found.
    2 View Details [218..324] PSI-BLAST 17.69897 No description for 2do0A was found.
    3 View Details [325..561] deduced N/A No confident structure predictions are available.
    4 View Details [562..632] PSI-BLAST 5.69897 No description for 2ditA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  0.787118623292657 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.0269483316710413 bayes_pls_golite062009
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  0.950788308762215 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.29562225149076 bayes_pls_golite062009
    4
    Term Confidence Notes
  • binding
    		•  0.950788308762215 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.29562225149076 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle