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View Structure Prediction Details

Protein: rump-PA
Organism: Drosophila melanogaster
Length: 632 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for rump-PA.

Description E-value Query
Range
Subject
Range
gi|55959639, gi|... - gi|66267552|gb|AAH94755.1| PABPC4 protein [Homo sapiens], gi|55962217|emb|CAI12298.1| poly(A) bindin...
gi|114555673 - gi|114555673|ref|XP_001170937.1| PREDICTED: poly A binding protein, cytoplasmic 4 isoform 1 [Pan tro...
290.0 [0..1] [502..57]

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Predicted Domain #1
Region A:
Residues: [1-217]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSMDASNSVE SREKERDRRG RGARGSRFTD ADGNGNGAGS QGGGVAARDR SRERRNCRVY  60
   61 ISNIPYDYRW QDLKDLFRRI VGSIEYVQLF FDESGKARGC GIVEFKDPEN VQKALEKMNR 120
  121 YEVNGRELVV KEDHGEQRDQ YGRIVRDGGG GGGGGGGVQG GNGGNNGGGG GGGRDHMDDR 180
  181 DRGFSRRDDD RLSGRNNFNM MSNDYNNSSN YNLYGLS

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.72
Match: 2ghpA
Description: No description for 2ghpA was found.

Predicted functions:

Term Confidence Notes
binding 0.787118623292657 bayes_pls_golite062009
nucleic acid binding 0.0269483316710413 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [218-324]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASFLESLGIS GPLHNKVFVA NLDYKVDNKK LKQVFKLAGK VQSVDLSLDK EGNSRGFAVI  60
   61 EYDHPVEAVQ AISMLDRQML FDRRMTVRLD RIPDKNEGIK LPEGLGG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.69897
Match: 2do0A
Description: No description for 2do0A was found.

Predicted Domain #3
Region A:
Residues: [325-561]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VGIGLGPNGE PLRDVAHNLP NGGQSQGQLL GNAQQGSQLG SVGSQPNSSA VSNATTNLLN  60
   61 NLTGVMFGNH AAVQPSPVAP VQKPSLGNNT GSGGLNLNNL NPSILAAVVG NLGNQGGNLS 120
  121 NPLLSSSLSN LGLNLGNSGN DDNLPPSNVG LSNNYSSGGT GGGNSYSSGN NYSGGGGSSN 180
  181 LGYNAYSSSG GMGGGNGGVG VDGNDYNTGN PLDVYGGGSN VGNSNVGSAN AVGASRK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
binding 0.950788308762215 bayes_pls_golite062009
nucleic acid binding 0.29562225149076 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [562-632]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SDTIIIKNVP ITCTWQTLRD KFREIGDVKF AEIRGNDVGV VRFFKERDAE LAIALMDGSR  60
   61 LDGRNIKVTY F

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.69897
Match: 2ditA
Description: No description for 2ditA was found.

Predicted functions:

Term Confidence Notes
binding 0.950788308762215 bayes_pls_golite062009
nucleic acid binding 0.29562225149076 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle