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Protein Overview: gi|28573155, gi|...

General Information:
Name(s) found: gi|28573155 [NCBI NR]
gi|28381197 [NCBI NR]
Description(s) found:
Found 7 descriptions.
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  • gi|28573155|ref|NP_731293.2| polychaetoid, isoform E [Drosophila melanogaster] [NCBI NR]
  • gi|28381197|gb|AAF54303.3| polychaetoid, isoform E [Drosophila melanogaster] [NCBI NR]
    • Organism: Drosophila melanogaster
    Length: 1167 amino acids

    Gene Ontology:
    Cellular Component: adherens junction [NAS][TAS]
    cell-cell adherens junction [IDA]
    Biological Process: dorsal closure [NAS][TAS]
    cell-cell adhesion [IMP]
    fusion cell fate specification [IMP]
    establishment or maintenance of cell polarity [NAS]
    JNK cascade [NAS]
    branch fusion, open tracheal system [IMP]
    regulation of JNK cascade [NAS]
    Molecular Function: protein binding [IEA]
    guanylate kinase activity [ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTREEEEEVR SLLSRHQERI MLDLGSTDLL AVLVKNSVLS QSEEDLLLKP YNAVTPTPSA  60
   61 AASATVEPPG SAPSLTKRKL SAVASSGSTA SGGSAGSGGS GSSRCASVNG DANCDSRSLT 120
  121 PSGGGPCSGL NDAEILRVQC SNLIDIIAKN GFEKFKQFCY AIECECPQLI EDLINDRLKT 180
  181 DAANLEDSRD GEKMQKEIET IDYIDKEKEN DRNRRAVSYG GDATSSPHSA TIPRAAPRRV 240
  241 ALMKDPPPPP PPKPQLGSKA DSVSHLASKY PQSEYNLIQK IDSNSTLTAP AQYQPQNFYA 300
  301 NTGTISSTNG YGSLLCHASS TTSPLAVRKR DKLLHRFSDA ATLGRKLKKK KNTNRTCRSM 360
  361 TEAIEMLADP VIEDEFFGDR TTWEYHTVAV TRVPGYGFGI AVSGGRDNPH FANGDPSIAV 420
  421 SDVLKGGPAE DRLQVNDRII SVNGVSLENV EYATAVQVLR DSGNTVQLVV KRRVPLNPIN 480
  481 AAGAVQHQHS HSLSSVGLMA NGSGGVAPTP ITSLSQPNSL NSSLVQNASS GQPIKVTLTK 540
  541 GGKKDDYGVV LGCRLFVKEI SSKAREQLNA NGYSLQEGDI ITRIHNTNCG DTMSLKEAKK 600
  601 IIDGCKERLN LVVLRDITNQ TAVSQLNLNN SASHQASGNI YATHQPQVSG CSSSNNNLED 660
  661 PYLPGGASYS SQNLYVQPPT RTSNGPNING NGLNDEKSNL TPRGRSRGPI MDGVSLQQLD 720
  721 RPVTPTRGRS AAIDEPPRPP PPRGSSGGAA QEDFYSSRRQ LYEERQSAEP RFISFQKEGS 780
  781 VGIRLTGGNE AGIFVTAVQP GSPASLQGLM PGDKILKVND MDMNGVTREE AVLFLLSLQD 840
  841 RIDLIVQYCK EEYDEVVTNQ RGDSFHIKTH FHCDNPSKGE MAFKAGDVFR VIDTLHNGVV 900
  901 GSWQVLKIGR GHQEMQRGVI PNKSRAEELA TAQFNATKKE MNANESRGNF FRRRRSTHRR 960
  961 SKSLSRENWD DVVFSDSISK FPAYERVVLR HPGFVRPVVL FGPVSDLARE RLAKDFPDKF1020
 1021 STPLQDDDKS AATSGKCRIV RLSNIRDVMD RGKHALLDIT PNAVDRLNYA QFYPVVIFLK1080
 1081 TDSKHVIKQL RHGLPKAAHK SSKKLLEQCQ KLERVWSHIF STQIALSDEE SWYRKLRDSI1140
 1141 DLQQSGAVWM SESKTKTKYI SSWSFPA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..84] deduced N/A No confident structure predictions are available.
    2 View Details [85..176] PSI-BLAST 17.30103 Solution structure of the second PDZ domain of human membrane associated guanylate kinase inverted-2 (MAGI-2)
    3 View Details [177..376] deduced N/A No confident structure predictions are available.
    4 View Details [377..470] PSI-BLAST 23.39794 No description for 2h2bA was found.
    5 View Details [471..760] FFAS03 3.59 solution structure of the split PH-PDZ Supramodule of alpha-Syntrophin
    6 View Details [761..859] PSI-BLAST 19.69897 Solution structure of the third PDZ domain of synapse-associated protein 102
    7 View Details [860..1167] PSI-BLAST 41.39794 Psd-95; Guanylate kinase-like domain of Psd-95

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  2.6196222853442 bayes_pls_golite062009
  • protein binding
    		•  2.35875654816667 bayes_pls_golite062009
  • signal transducer activity
    		•  1.06018756723145 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.06018756723145 bayes_pls_golite062009
  • protein domain specific binding
    		•  0.64214865642772 bayes_pls_golite062009
  • cell adhesion molecule binding
    		•  0.403457741099606 bayes_pls_golite062009
  • receptor binding
    		•  0.359972518335054 bayes_pls_golite062009
  • PDZ domain binding
    		•  0.0377679976799299 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6
    Term Confidence Notes
  • binding
    		•  2.6196222853442 bayes_pls_golite062009
  • protein binding
    		•  2.35875654816667 bayes_pls_golite062009
  • signal transducer activity
    		•  1.06018756723145 bayes_pls_golite062009
  • molecular transducer activity
    		•  1.06018756723145 bayes_pls_golite062009
  • protein domain specific binding
    		•  0.64214865642772 bayes_pls_golite062009
  • cell adhesion molecule binding
    		•  0.403457741099606 bayes_pls_golite062009
  • receptor binding
    		•  0.359972518335054 bayes_pls_golite062009
  • PDZ domain binding
    		•  0.0377679976799299 bayes_pls_golite062009
    7 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle