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Protein Overview: sas-PB, FBpp0306906

General Information:
Name(s) found: FBpp0306906 [FlyBase]
sas-PB / FBpp0081089 [FlyBase]
Description(s) found:
Found 28 descriptions.
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  • type=protein; loc=3R:join(2990243..2990582,2999833..3001118,3003932..3004217,3004426..3005058,3005121..3005363,3005736..3006770,3007279..3008304,3008533..3008757,3008826..3008833); ID=FBpp0306906; name=sas-PD; parent=FBgn0002306,FBtr0334885; dbxref=FlyBase:FBpp0306906,FlyBase_Annotation_IDs:CG2507-PD,REFSEQ:NP_001262337,GB_protein:AGB95720; MD5=65f5578b80e173e28d5f34f6171ce1f2; length=1693; release=r5.56; species=Dmel; [FlyBase]
  • The gene stranded at second is referred to in FlyBase by the symbol Dmel\sas (CG2507, FBgn0002306). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:2988551..3009424. It has the cytological map location 84C8-84D1. It is reported to have molecular function</span>: receptor activity. There is experimental evidence that it is involved in the biological process</span>: instar larval development. 25 alleles are reported. The phenotypes of these alleles are annotated with: larval trachea; larval cuticle; larval tracheal system. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1693 amino acids

    Gene Ontology:
    Cellular Component: integral to plasma membrane [NAS]
    apical plasma membrane [NAS]
    Biological Process: instar larval development [IMP]
    Molecular Function: receptor activity [NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQTCRRRKAS GGQSTIKWSR MCLATLCGLL LLGIQIERAA SAPAGEDAAA TTMPPLDTTT  60
   61 DAPDAVAATT TPATTAAEQS SSISSITTEA ADGSTTSTTT TTEAANKSNA TETDFTTNVP 120
  121 VASSLPEETS VRSTSIEPIT STEPTTTPRQ ETEGPDQHMV FSNTEPDQSH IQHIPLRDEH 180
  181 AESSGADDAT TEMQRQREQD QQQNELNQIS NEQDDVVKDL NNFRHPATLI TASNSNSEEN 240
  241 VEIESDKQVE TTTTAVPAAA TSTSTEATGT PPTGTPATST STVPNEREED PYHVHILSEN 300
  301 HDRLAEHEDY QMLSTSTEES STTSTTSTTN STTESGIVAG IVVSQENKAT AEPSTATEST 360
  361 SISTSTTTAA TAATSTTSRA RAMHMNDPED EAATTIMPDS ESVPVINIVE GQHMLQQEDQ 420
  421 KDEEEEGVVK ESESSSTTEA STTTTEPSPF VAFAGEGRSA GGGNDIELFL HHNGSTHEQL 480
  481 MDLSDVSMDG DQNEGSSKTE SSTTSTTTTT AQPETEMPKI VEITASGDTM QRECLANNKS 540
  541 YKHGELMERD CDERCTCNRG DWMCEPRCRG LSYPRGSQRS MANPNCLEKM VEEDECCRVM 600
  601 ECSEPQLEPT VVATEGAAPS TNGTGESAVT LPTTDDEATP KPRTDCHYNS GVYKFRERLE 660
  661 IGCEQICHCA EGGVMDCRPR CPERNHTRLD KCVYVKDPKD VCCQLELCDV TLDDHEQQPT 720
  721 PLQSNNNEDP EEIDPFRFQE QARDAGGAKP TCTFKGAEYD VGQQFRDGCD QLCICNEQGI 780
  781 HCAKLECPSN FGLDVQDPHC IRWEPVPADF KPSPPNCCPE SMRCVDNGTC SYQGVQIENW 840
  841 SPVPANLTGC DQHCYCENGR VECRAACPPV PALPPADLPC HPALARLLPI PDDECCKHWM 900
  901 CAPQIPKIGG AGQDEETEAT STHSSIPANE TTTTTATANK STSIPSKVPQ IKKDEEKRPP 960
  961 ASGAFYPTLD GKPPKSIGGL GIFEKPEKPE KAHKKVQHQQ QQHQQQEQQE QQQHQNDVIF1020
 1021 DGDRTEEQEE PLPPNGGFVP FQFGQQHPHQ PHLGPYGFYN PVKPVYEDYN PYEPYDINPN1080
 1081 GTPQGKPPPV PTSQSDLFNI LGAEQPGHPV HPGHGGPPRI HPGQTQKDNH NLGPQVRIEQ1140
 1141 ILQHLQQTVP GGPPPPPPHQ QHQSLTPQLH PQQQQISQQH PGHYVPIVHS GVPPPPPGHG1200
 1201 IAIVDGQTVA YESYPVIPGL GVPQHHPQQH QTTPQQHLQQ TILPSSSTTS GLSTQASEHS1260
 1261 LHQNQGKLAK QQQSGANNLQ PDIEVHTLEA IDPRSIRIVF TVPQVYVNLH GRVELRYSNG1320
 1321 PSNDTSTWEQ QIFAPPEDLI ATSQMEFDLP SLEPNSLYKV KITLILRDLN SQPTSSIYTV1380
 1381 KTPPERTITP PPPFPDYRPD FQDIFKNVED PELTVSETNA SWLQLTWKKL GDDQMEYVDG1440
 1441 VQLRYKELTG MIYSSTPLIH RTLTSYTIQN LQPDTGYEIG LYYIPLAGHG AELRAGHMIK1500
 1501 VRTAQKVDVY GFDVTVNVTK VKTQSVEISW NGVPYPEDKF VHIYRAIYQS DAGKEDSSVF1560
 1561 KVAKRDSTTG TLIMDLKPGT KYRLWLEMYL TNGNTKKSNV VNFITKPGGP ATPGKTGKLL1620
 1621 TAGTDQPVGD YYGPLVVVSV IAALAIMSTL ALLLIITRRR VHQTASITPP RKSDAAYDNP1680
 1681 SYKVEIQQET MNL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..301] deduced N/A No confident structure predictions are available.
    2 View Details [302..459] MSA 3.204986 View MSA. No confident structure predictions are available.
    3 View Details [460..537] deduced N/A No confident structure predictions are available.
    4 View Details [538..686] FFAS03 0.954 Crystal Structure of Pyrogallol-Phloroglucinol Transhydroxylase from Pelobacter acidigallici
    5 View Details [687..1001] PSI-BLAST 16.39794 Hybrid domain of integrin beta; Integrin beta A domain; Integrin beta tail domain; Integrin beta EGF-like domains
    6 View Details [1002..1192] deduced N/A No confident structure predictions are available.
    7 View Details [1193..1613] PSI-BLAST 22.39794 No description for 2dtgE was found.
    8 View Details [1614..1693] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • binding
    		•  0.454938403386338 bayes_pls_golite062009
  • protein binding
    		•  0.270732535872106 bayes_pls_golite062009
    5 No functions predicted.
    6 No functions predicted.
    7
    Term Confidence Notes
  • receptor activity
    		•  3.27855575524173 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  3.23276190218547 bayes_pls_golite062009
  • protein binding
    		•  2.21770026586875 bayes_pls_golite062009
  • binding
    		•  2.0480532566419 bayes_pls_golite062009
  • signal transducer activity
    		•  2.00039705185957 bayes_pls_golite062009
  • molecular transducer activity
    		•  2.00039705185957 bayes_pls_golite062009
  • cytokine binding
    		•  1.90627686584923 bayes_pls_golite062009
  • cytokine receptor activity
    		•  1.32127809692757 bayes_pls_golite062009
  • growth factor binding
    		•  1.07003653734093 bayes_pls_golite062009
  • receptor binding
    		•  0.44321055668528 bayes_pls_golite062009
    8 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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