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View Structure Prediction Details

Protein: sas-PB, FBpp0306906
Organism: Drosophila melanogaster
Length: 1693 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for sas-PB, FBpp0306906.

Description E-value Query
Range
Subject
Range
gi|157105058, gi... - gi|157105058|ref|XP_001648698.1| hypothetical protein AaeL_AAEL004214 [Aedes aegypti], gi|108880193|...
762.0 [0..543] [1692..1]

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Predicted Domain #1
Region A:
Residues: [1-301]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQTCRRRKAS GGQSTIKWSR MCLATLCGLL LLGIQIERAA SAPAGEDAAA TTMPPLDTTT  60
   61 DAPDAVAATT TPATTAAEQS SSISSITTEA ADGSTTSTTT TTEAANKSNA TETDFTTNVP 120
  121 VASSLPEETS VRSTSIEPIT STEPTTTPRQ ETEGPDQHMV FSNTEPDQSH IQHIPLRDEH 180
  181 AESSGADDAT TEMQRQREQD QQQNELNQIS NEQDDVVKDL NNFRHPATLI TASNSNSEEN 240
  241 VEIESDKQVE TTTTAVPAAA TSTSTEATGT PPTGTPATST STVPNEREED PYHVHILSEN 300
  301 H

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [302-459]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DRLAEHEDYQ MLSTSTEESS TTSTTSTTNS TTESGIVAGI VVSQENKATA EPSTATESTS  60
   61 ISTSTTTAAT AATSTTSRAR AMHMNDPEDE AATTIMPDSE SVPVINIVEG QHMLQQEDQK 120
  121 DEEEEGVVKE SESSSTTEAS TTTTEPSPFV AFAGEGRS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [460-537]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AGGGNDIELF LHHNGSTHEQ LMDLSDVSMD GDQNEGSSKT ESSTTSTTTT TAQPETEMPK  60
   61 IVEITASGDT MQRECLAN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [538-686]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NKSYKHGELM ERDCDERCTC NRGDWMCEPR CRGLSYPRGS QRSMANPNCL EKMVEEDECC  60
   61 RVMECSEPQL EPTVVATEGA APSTNGTGES AVTLPTTDDE ATPKPRTDCH YNSGVYKFRE 120
  121 RLEIGCEQIC HCAEGGVMDC RPRCPERNH

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.954
Match: 1ti2B
Description: Crystal Structure of Pyrogallol-Phloroglucinol Transhydroxylase from Pelobacter acidigallici
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.454938403386338 bayes_pls_golite062009
protein binding 0.270732535872106 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [687-1001]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TRLDKCVYVK DPKDVCCQLE LCDVTLDDHE QQPTPLQSNN NEDPEEIDPF RFQEQARDAG  60
   61 GAKPTCTFKG AEYDVGQQFR DGCDQLCICN EQGIHCAKLE CPSNFGLDVQ DPHCIRWEPV 120
  121 PADFKPSPPN CCPESMRCVD NGTCSYQGVQ IENWSPVPAN LTGCDQHCYC ENGRVECRAA 180
  181 CPPVPALPPA DLPCHPALAR LLPIPDDECC KHWMCAPQIP KIGGAGQDEE TEATSTHSSI 240
  241 PANETTTTTA TANKSTSIPS KVPQIKKDEE KRPPASGAFY PTLDGKPPKS IGGLGIFEKP 300
  301 EKPEKAHKKV QHQQQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 16.39794
Match: 1jv2B
Description: Hybrid domain of integrin beta; Integrin beta A domain; Integrin beta tail domain; Integrin beta EGF-like domains
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [1002-1192]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QHQQQEQQEQ QQHQNDVIFD GDRTEEQEEP LPPNGGFVPF QFGQQHPHQP HLGPYGFYNP  60
   61 VKPVYEDYNP YEPYDINPNG TPQGKPPPVP TSQSDLFNIL GAEQPGHPVH PGHGGPPRIH 120
  121 PGQTQKDNHN LGPQVRIEQI LQHLQQTVPG GPPPPPPHQQ HQSLTPQLHP QQQQISQQHP 180
  181 GHYVPIVHSG V

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [1193-1613]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPPPPGHGIA IVDGQTVAYE SYPVIPGLGV PQHHPQQHQT TPQQHLQQTI LPSSSTTSGL  60
   61 STQASEHSLH QNQGKLAKQQ QSGANNLQPD IEVHTLEAID PRSIRIVFTV PQVYVNLHGR 120
  121 VELRYSNGPS NDTSTWEQQI FAPPEDLIAT SQMEFDLPSL EPNSLYKVKI TLILRDLNSQ 180
  181 PTSSIYTVKT PPERTITPPP PFPDYRPDFQ DIFKNVEDPE LTVSETNASW LQLTWKKLGD 240
  241 DQMEYVDGVQ LRYKELTGMI YSSTPLIHRT LTSYTIQNLQ PDTGYEIGLY YIPLAGHGAE 300
  301 LRAGHMIKVR TAQKVDVYGF DVTVNVTKVK TQSVEISWNG VPYPEDKFVH IYRAIYQSDA 360
  361 GKEDSSVFKV AKRDSTTGTL IMDLKPGTKY RLWLEMYLTN GNTKKSNVVN FITKPGGPAT 420
  421 P

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 22.39794
Match: 2dtgE
Description: No description for 2dtgE was found.

Predicted functions:

Term Confidence Notes
receptor activity 3.27855575524173 bayes_pls_golite062009
transmembrane receptor activity 3.23276190218547 bayes_pls_golite062009
protein binding 2.21770026586875 bayes_pls_golite062009
binding 2.0480532566419 bayes_pls_golite062009
signal transducer activity 2.00039705185957 bayes_pls_golite062009
molecular transducer activity 2.00039705185957 bayes_pls_golite062009
cytokine binding 1.90627686584923 bayes_pls_golite062009
cytokine receptor activity 1.32127809692757 bayes_pls_golite062009
growth factor binding 1.07003653734093 bayes_pls_golite062009
receptor binding 0.44321055668528 bayes_pls_golite062009

Predicted Domain #8
Region A:
Residues: [1614-1693]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKTGKLLTAG TDQPVGDYYG PLVVVSVIAA LAIMSTLALL LIITRRRVHQ TASITPPRKS  60
   61 DAAYDNPSYK VEIQQETMNL 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle