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Protein Overview: agt-PA

General Information:
Name(s) found: agt-PA / FBpp0081195 [FlyBase]
Description(s) found:
Found 28 descriptions.
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  • The gene O-6-alkylguanine-DNA alkyltransferase is referred to in FlyBase by the symbol Dmel\agt (CG1303, FBgn0024912). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:2485130..2485822. It has the cytological map location 84A1. There is experimental evidence that it has the molecular function</span>: methylated-DNA-[protein]-cysteine S-methyltransferase activity. There is experimental evidence that it is involved in the biological process</span>: DNA dealkylation. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 194 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: DNA dealkylation involved in DNA repair [IDA]
    Molecular Function: methylated-DNA-[protein]-cysteine S-methyltransferase activity [IDA][ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTMWIGQNTQ IRLVPLKDPP KTIRYSFLAT KFGQMMMGVI NPISGDSKDQ VAIGVLHFVI  60
   61 KDNVSTYNEV QERWPKSELW KDDDAVKLVA DKLFESDKEN SQAIPIAIYG TDFQLSVWRA 120
  121 LVHMKRGETC TYSQLAERMG RPTAVRAVAS AVAKNELAIL IPCHRVVSQN GASKYHWGAA 180
  181 LKQLLLADEK SKNY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..194] PSI-BLAST 46.045757 ADA O6-METHYLGUANINE-DNA METHYLTRANSFERASE FROM ESCHERICHIA COLI

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • methylated-DNA-[protein]-cysteine S-methyltransferase activity
    		•  3.9938943760254 bayes_pls_golite062009
  • S-methyltransferase activity
    		•  2.96219931728042 bayes_pls_golite062009
  • catalytic activity
    		•  2.27882522649583 bayes_pls_golite062009
  • methyltransferase activity
    		•  1.63681159093596 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  1.6341981985862 bayes_pls_golite062009
  • transferase activity
    		•  1.42883081715544 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle