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Protein Overview: Rm62-PA

General Information:
Name(s) found: Rm62-PA / FBpp0078301 [FlyBase]
Description(s) found:
Found 23 descriptions.
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  • The gene Rm62 is referred to in FlyBase by the symbol Dmel\Rm62 (CG10279, FBgn0003261). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:1826153..1834301. It has the cytological map location 83D1-83D2. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: RNA interference; antimicrobial humoral response; regulation of alternative nuclear mRNA splicing, via spliceosome. 38 alleles are reported. The phenotypes of these alleles are annotated with: dorsocentral bristle; scutellar bristle; egg chamber; pigment cell. It has 9 annotated transcripts and 9 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 719 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IC]
    polytene chromosome puff [IDA]
    catalytic step 2 spliceosome [IDA]
    precatalytic spliceosome [IDA]
    Biological Process: regulation of alternative nuclear mRNA splicing, via spliceosome [IMP]
    antimicrobial humoral response [IMP]
    RNA interference [IMP]
    nuclear mRNA splicing, via spliceosome [IC]
    Molecular Function: nucleic acid binding [IEA]
    ATP binding [IEA]
    protein binding [IPI]
    mRNA binding [ISS]
    ATP-dependent RNA helicase activity [ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLKLVQYIAP RVGGATPRPT ACGWGNLLLI SPRSGASSEK CITQRRHFLF SSASSSGTFA  60
   61 SSSSLCTEQR QQFHGSRRNR ETILFPSTYS SLQAQSQRAF RDSSKPDSDD YVDSIPKAEQ 120
  121 RTRTRKSLFN DPDERTEEIK IEGVMAPHDR DFGHSGRGGR GGDRGGDDRR GGGGGGNRFG 180
  181 GGGGGGDYHG IRNGRVEKRR DDRGGGNRFG GGGGFGDRRG GGGGGSQDLP MRPVDFSNLA 240
  241 PFKKNFYQEH PNVANRSPYE VQRYREEQEI TVRGQVPNPI QDFSEVHLPD YVMKEIRRQG 300
  301 YKAPTAIQAQ GWPIAMSGSN FVGIAKTGSG KTLGYILPAI VHINNQQPLQ RGDGPIALVL 360
  361 APTRELAQQI QQVATEFGSS SYVRNTCVFG GAPKGGQMRD LQRGCEIVIA TPGRLIDFLS 420
  421 AGSTNLKRCT YLVLDEADRM LDMGFEPQIR KIVSQIRPDR QTLMWSATWP KEVKQLAEDF 480
  481 LGNYIQINIG SLELSANHNI RQVVDVCDEF SKEEKLKTLL SDIYDTSESP GKIIIFVETK 540
  541 RRVDNLVRFI RSFGVRCGAI HGDKSQSERD FVLREFRSGK SNILVATDVA ARGLDVDGIK 600
  601 YVINFDYPQN SEDYIHRIGR TGRSNTKGTS FAFFTKNNAK QAKALVDVLR EANQEINPAL 660
  661 ENLARNSRYD GGGGRSRYGG GGGGGRFGGG GFKKGSLSNG RGFGGGGGGG GEGRHSRFD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..178] MSA 1.256994 View MSA. No confident structure predictions are available.
    2 View Details [179..273] PSI-BLAST 7.39794 Crystal structure of the UvsW helicase from Bacteriophage T4
    3 View Details [274..719] PSI-BLAST 97.154902 No description for 2i4iA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.59

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle