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Protein Overview: ECSIT-PA

General Information:
Name(s) found: ECSIT-PA / FBpp0078296 [FlyBase]
Description(s) found:
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  • gi|7296657|gb|AAF51937.1| ECSIT [Drosophila melanogaster] [NCBI NR]
  • gi|24644458|ref|NP_649602.2| ECSIT [Drosophila melanogaster] [NCBI NR]
  • gi|211938495|gb|ACJ13144.1| FI02802p [Drosophila melanogaster] [NCBI NR]
  • gi|150382526|sp|Q9U6M0.2|ECSIT_DROME RecName: Full=Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial; Flags: Precursor [NCBI NR]
  • Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial OS=Drosophila melanogaster GN=ECSIT PE=1 SV=2 [Swiss-Prot]
  • The gene ECSIT is referred to in FlyBase by the symbol Dmel\ECSIT (CG10610, FBgn0028436). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:1682307..1683636. It has the cytological map location 83C5. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: innate immune response. 7 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG10610-PA translation from_gene[CG10610 ECSIT FBgn0028436] seq_release:3 mol_weight=47065 cds_boundaries:(3R:1,682,390..1,683,616[+]) aa_length:409 transcript_info:[CG10610-RA seq_release:3] gene_info:[gene symbol:ECSIT FBgn0028436 gene_boundaries:(3 [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9VNJ6) ECSIT protein [DrosMelano7227.FASTAC.txt]
  • (AE003601) ECSIT gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG10610-PA [Drosophila melanogaster]gi|24644458|ref|NP_649602.2| CG10610-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3R:1682393..1683622; ID=FBpp0078296; name=ECSIT-PA; parent=FBgn0028436,FBtr0078647; dbxref=FlyBase:FBpp0078296,FlyBase_Annotation_IDs:CG10610-PA,GB_protein:AAF51937.1,REFSEQ:NP_649602,GB_protein:AAF51937; MD5=b882e8e1ea48c44c80bf008f98b4 [fly-100309-contam.fasta]
  • ECSIT CG10610-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG10610-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3R:1682393..1683622; ID=FBpp0078296; name=ECSIT-PA; parent=FBgn0028436,FBtr0078647; dbxref=FlyBase:FBpp0078296,FlyBase_Annotation_IDs:CG10610-PA,GB_protein:AAF51937.1,REFSEQ:NP_649602,GB_protein:AAF51937; MD5=b882e8e1ea48c44c80bf008f98b48ded; length=409; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3R:1682393..1683622; ID=FBpp0078296; name=ECSIT-PA; parent=FBgn0028436,FBtr0078647; dbxref=FlyBase:FBpp0078296,FlyBase_Annotation_IDs:CG10610-PA,GB_protein:AAF51937.1,REFSEQ:NP_649602,GB_protein:AAF51937; MD5=b882e8e1ea48c44c80bf008f98b48ded; length=409; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • FI02802p OS=Drosophila melanogaster GN=ECSIT-RA PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=3R:1682393..1683622; ID=FBpp0078296; name=ECSIT-PA; parent=FBgn0028436,FBtr0078647; dbxref=FlyBase:FBpp0078296,FlyBase_Annotation_IDs:CG10610-PA,GB_protein:AAF51937.1,REFSEQ:NP_649602,GB_protein:AAF51937,FlyMine:FBpp0078296,modMine:FBpp0078296; MD5=b882e8e1ea48c44c80bf008f98b48ded; length=409; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3R:5856671..5857900; ID=FBpp0078296; name=ECSIT-PA; parent=FBgn0028436,FBtr0078647; dbxref=FlyBase:FBpp0078296,FlyBase_Annotation_IDs:CG10610-PA,GB_protein:AAF51937.1,REFSEQ:NP_649602,GB_protein:AAF51937,FlyMine:FBpp0078296,modMine:FBpp0078296; MD5=b882e8e1ea48c44c80bf008f98b48ded; length=409; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3R:5856671..5857900; ID=FBpp0078296; name=ECSIT-PA; parent=FBgn0028436,FBtr0078647; dbxref=FlyBase:FBpp0078296,FlyBase_Annotation_IDs:CG10610-PA,GB_protein:AAF51937.1,REFSEQ:NP_649602,GB_protein:AAF51937,FlyMine:FBpp0078296,modMine:FBpp0078296; MD5=b882e8e1ea48c44c80bf008f98b48ded; length=409; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FBpp0078296 type=protein; loc=3R:5856671..5857900; ID=FBpp0078296; name=ECSIT-PA; parent=FBgn0028436,FBtr0078647; dbxref=FlyBase:FBpp0078296,FlyBase_Annotation_IDs:CG10610-PA,GB_protein:AAF51937.1,REFSEQ:NP_649602,GB_protein:AAF51937,FlyMine:FBpp0078296,modMine:FBpp0078296; MD5=b882e8e1ea48c44c80bf008f98b48ded; length=409; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3R:5856671..5857900; ID=FBpp0078296; name=ECSIT-PA; parent=FBgn0028436,FBtr0078647; dbxref=FlyBase:FBpp0078296,FlyBase_Annotation_IDs:CG10610-PA,GB_protein:AAF51937.1,REFSEQ:NP_649602,GB_protein:AAF51937,UniProt/Swiss-Prot:Q9U6M0,FlyMine:FBpp0078296,modMine:FBpp0078296; MD5=b882e8e1ea48c44c80bf008f98b48ded; length=409; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 409 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: Toll signaling pathway [NAS]
    signal transduction [NAS]
    innate immune response [IDA]
    defense response [NAS]
    Molecular Function: protein binding [IPI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRRAQCLLR LHGNGGHSLV SRFRNYATDE GNPKQNPNPN PRAQKPGTKN LPALRNPFAA  60
   61 AQDRTKNSYL TMVEIFQERD VHRRNHVEFI YAALKNMADF GVERDLEVYK ALINVMPKGK 120
  121 FIPTNMFQAE FMHYPKQQQC IIDLLEQMED CGVMPDHEME AMLLNVFGRQ GHPLRKYWRM 180
  181 MYWMPKFKNL SPWPLPDPVP DDTLEMAKLA LERMCTVDLR SKITVFETSE LKDAIDDTWI 240
  241 VSGMSPEQEK LLREHSRQKA LYIEGPFHIW LRNRRINYFT LRADADSEFL SELDERQLDE 300
  301 DDVSHIEVPF FGRAPPRRHN QLGKLRSVHQ QDDGTIMAIC ATGTSTKDSL LSWIRLLEAN 360
  361 GNPSIGEVPV LFRFTSEVPA KAEEIEGGAS VPATSDNSSQ DEHISSRQK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..235] MSA 2.017919 View MSA. No confident structure predictions are available.
    2 View Details [236..409] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle