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Protein Overview: disp-PA

General Information:
Name(s) found: disp-PA / FBpp0078314 [FlyBase]
Description(s) found:
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  • gi|74870086|sp|Q9VNJ5.1|DISP_DROME RecName: Full=Protein dispatched [NCBI NR]
  • gi|7296658|gb|AAF51938.1| dispatched [Drosophila melanogaster] [NCBI NR]
  • gi|24644456|ref|NP_524734.2| dispatched [Drosophila melanogaster] [NCBI NR]
  • gi|211938479|gb|ACJ13136.1| FI02022p [Drosophila melanogaster] [NCBI NR]
  • Protein dispatched OS=Drosophila melanogaster GN=disp PE=1 SV=1 [Swiss-Prot]
  • The gene dispatched is referred to in FlyBase by the symbol Dmel\disp (CG2019, FBgn0029088). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:1675416..1682033. It has the cytological map location 83C5. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: hedgehog receptor activity. There is experimental evidence that it is involved in the biological process</span>: smoothened signaling pathway; pole cell migration. 9 alleles are reported. The phenotype of these alleles is annotated with: denticle belt. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG2019-PA translation from_gene[CG2019 disp FBgn0029088] seq_release:3 mol_weight=138980 cds_boundaries:(3R:1,676,243..1,681,627[-]) aa_length:1218 transcript_info:[CG2019-RA seq_release:3] gene_info:[gene symbol:disp FBgn0029088 gene_boundaries:(3R:1 [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9VNJ5) CG2019 protein [DrosMelano7227.FASTAC.txt]
  • (AE003601) disp gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG2019-PA [Drosophila melanogaster]gi|24644456|ref|NP_524734.2| CG2019-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3R:complement(1676243..1676480,1676613..1677593,1677778..1678416,1678489..1679031,1679843..1679934,1680066..1681073,1681475..1681630); ID=FBpp0078314; name=disp-PA; parent=FBgn0029088,FBtr0078665; dbxref=FlyBase:FBpp0078314,FlyBase_Annot [fly-100309-contam.fasta]
  • dispatched CG2019-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG2019-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3R:complement(1676243..1676480,1676613..1677593,1677778..1678416,1678489..1679031,1679843..1679934,1680066..1681073,1681475..1681630); ID=FBpp0078314; name=disp-PA; parent=FBgn0029088,FBtr0078665; dbxref=FlyBase:FBpp0078314,FlyBase_Annotation_IDs:CG2019-PA,GB_protein:AAF51938.1,REFSEQ:NP_524734,GB_protein:AAF51938; MD5=529892fd80cee186b7dcbd0a2b54adac; length=1218; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3R:complement(1676243..1676480,1676613..1677593,1677778..1678416,1678489..1679031,1679843..1679934,1680066..1681073,1681475..1681630); ID=FBpp0078314; name=disp-PA; parent=FBgn0029088,FBtr0078665; dbxref=FlyBase:FBpp0078314,FlyBase_Annotation_IDs:CG2019-PA,GB_protein:AAF51938.1,REFSEQ:NP_524734,GB_protein:AAF51938; MD5=529892fd80cee186b7dcbd0a2b54adac; length=1218; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • type=protein; loc=3R:complement(1676243..1676480,1676613..1677593,1677778..1678416,1678489..1679031,1679843..1679934,1680066..1681073,1681475..1681630); ID=FBpp0078314; name=disp-PA; parent=FBgn0029088,FBtr0078665; dbxref=FlyBase:FBpp0078314,FlyBase_Annotation_IDs:CG2019-PA,GB_protein:AAF51938.1,REFSEQ:NP_524734,GB_protein:AAF51938,FlyMine:FBpp0078314,modMine:FBpp0078314; MD5=529892fd80cee186b7dcbd0a2b54adac; length=1218; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3R:complement(join(5855753..5855908,5854344..5855351,5854121..5854212,5852767..5853309,5852056..5852694,5850891..5851871,5850521..5850758)); ID=FBpp0078314; name=disp-PA; parent=FBgn0029088,FBtr0078665; dbxref=FlyBase:FBpp0078314,FlyBase_Annotation_IDs:CG2019-PA,GB_protein:AAF51938.1,REFSEQ:NP_524734,GB_protein:AAF51938,FlyMine:FBpp0078314,modMine:FBpp0078314; MD5=529892fd80cee186b7dcbd0a2b54adac; length=1218; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3R:complement(join(5855753..5855908,5854344..5855351,5854121..5854212,5852767..5853309,5852056..5852694,5850891..5851871,5850521..5850758)); ID=FBpp0078314; name=disp-PA; parent=FBgn0029088,FBtr0078665; dbxref=FlyBase:FBpp0078314,FlyBase_Annotation_IDs:CG2019-PA,GB_protein:AAF51938.1,REFSEQ:NP_524734,GB_protein:AAF51938,FlyMine:FBpp0078314,modMine:FBpp0078314; MD5=529892fd80cee186b7dcbd0a2b54adac; length=1218; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FBpp0078314 type=protein; loc=3R:complement(join(5855753..5855908,5854344..5855351,5854121..5854212,5852767..5853309,5852056..5852694,5850891..5851871,5850521..5850758)); ID=FBpp0078314; name=disp-PA; parent=FBgn0029088,FBtr0078665; dbxref=FlyBase:FBpp0078314,FlyBase_Annotation_IDs:CG2019-PA,GB_protein:AAF51938.1,REFSEQ:NP_524734,GB_protein:AAF51938,FlyMine:FBpp0078314,modMine:FBpp0078314; MD5=529892fd80cee186b7dcbd0a2b54adac; length=1218; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3R:complement(join(5855753..5855908,5854344..5855351,5854121..5854212,5852767..5853309,5852056..5852694,5850891..5851871,5850521..5850758)); ID=FBpp0078314; name=disp-PA; parent=FBgn0029088,FBtr0078665; dbxref=FlyBase:FBpp0078314,FlyBase_Annotation_IDs:CG2019-PA,GB_protein:AAF51938.1,REFSEQ:NP_524734,GB_protein:AAF51938,UniProt/Swiss-Prot:Q9VNJ5,FlyMine:FBpp0078314,modMine:FBpp0078314; MD5=529892fd80cee186b7dcbd0a2b54adac; length=1218; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 1218 amino acids

    Gene Ontology:
    Cellular Component: membrane [NAS]
    integral to membrane [IEA][ISS]
    Biological Process: pole cell migration [IGI]
    smoothened signaling pathway [IMP]
    exocytosis [TAS]
    Molecular Function: hedgehog receptor activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLCFDSERMN WYYHVLARRP YLVVVSIAVY CVACIIVALV LNKLPDFSDP TLGFETRGTK  60
   61 IGERLTAWYN LLQETDHHGA LFSNPSDLWE RRRVEQGYVE TKLHPNHRRR KNKHKNRNKN 120
  121 KRRKEQNQSS HEHHDVAQKM MQFKKRLKAT SSPSPNLGFD TWIGDSGVFR DYEITNDSAS 180
  181 SSLEPTRRTE QIEYGHNTTS VDEEEHQQRV QTKKSTWRLL KQAATLPTDG WADMHRRQPI 240
  241 EGFFCDSSPR KEYSHFVVQR IGPNATDSLF DLNGLLAMCQ LQDQITEVPS YRAFCEPEML 300
  301 TTECCRPWSL PNYAAMLANK SSCFDLTTED VTSLHTLLLG CYEYFHDLKM DNHCNEIPHC 360
  361 RAPEECKRLN IVFNVLNFLT DFSFIKSNDS NVYLKYAMIF IPVAQSNRLL PLFHEWEDVE 420
  421 LINELVEVVA MDLGLENELF NELLLTDVWL VSLGGTFVMA SVWLYTGSAF ITLMSCVAIC 480
  481 FSLGLAYFFY AIVLEFEFFP YMNLLAVVVI IGIGADDVFL FLKIWHCVLT ERFSNRCTLT 540
  541 TQSQSALPTL ENSDHTESLE NIMALTMRHA AASMFVTSLT TAGAFYASYS SSITAIKCFG 600
  601 IFAGTVVVTN YLLMITWLPA SVSIMERLFA TRMSCHHPMS IKLIHACKKS INRFCQMFEE 660
  661 CITKSIMNYA YLWLLIFGAL GASSAVIVFW YPGLQLPEKS HFQLFVSKHP FEVYSSLKQQ 720
  721 FWFEKPLQAY ENFKMHMHFV WGVQAVDDGD YTNPNSYGHL HYDNNFNVSS RPAQLWILDF 780
  781 CQSVRQQPFY KETLGMLLPN CFIENLIDYM KRRCIDDMDS TRKDRSPCCD AQFPFEPHIF 840
  841 EYCLPQSISN MYDTTFFRPG VAGPKFAEAP RLETEDYLGM SGNESAEYST NGSFTPLLVK 900
  901 ALVIEFESNV AYSTIYANIR QFYESVEHWF QMQLKTAPPE LQGGWFTSDL KFYNVQDTLS 960
  961 HDTFVAICLA MAASLAVLLC FTVNILISIY AVLTVSLSIF NTVAVLILLG WQLNILESIA1020
 1021 VSTAIGLAVD FSLHYGIHYR MSPVKERLAA TQFVLSRIIG PTVMAATTTG LAGGIMMASN1080
 1081 ILPYIQIGVF LVVVMIVSWF YATFFLMSLL RVAGPQHGFL ELKWPLWSKR SSGSSKFYER1140
 1141 KPSQVIASEQ LLTPTSSAIV ELANSETHEL ESLNSNSLIK TISGIESAHA LSSLPRDFEH1200
 1201 SFQTMHECKY QTYPSTSN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..253] deduced N/A No confident structure predictions are available.
    2 View Details [254..1125] PSI-BLAST 177.0 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains; Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains; Multidrug efflux transporter AcrB transmembrane domain
    3 View Details [1126..1218] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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