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Protein Overview: CG16708-PA, CG16...

General Information:
Name(s) found: CG16708-PB / FBpp0078447 [FlyBase]
CG16708-PA / FBpp0078446 [FlyBase]
Description(s) found:
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  • gi|24644207|ref|NP_649530.2| CG16708, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|24644205|ref|NP_730923.1| CG16708, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|23170447|gb|AAN13278.1| CG16708, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|23170446|gb|AAF52040.2| CG16708, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|159884165|gb|ABX00761.1| LD42647p [Drosophila melanogaster] [NCBI NR]
  • This gene is referred to in FlyBase by the symbol Dmel\CG16708 (CG16708, FBgn0037315). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:1184585..1194027. It has the cytological map location 82F11-83A1. Based on sequence similarity, it is predicted to have molecular function</span>: D-erythro-sphingosine kinase activity. There is experimental evidence that it is involved in the biological process</span>: autophagic cell death; salivary gland cell autophagic cell death. 10 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • >CG16708-PA translation from_gene[CG16708 CG16708 FBgn0037315] seq_release:3 mol_weight=75691 cds_boundaries:(3R:1,184,880..1,187,428[-]) aa_length:687 transcript_info:[CG16708-RA seq_release:3] gene_info:[gene symbol:CG16708 FBgn0037315 gene_boundarie [hmr_yeast5_DM3-1_pombe.fasta]
  • >CG16708-PB translation from_gene[CG16708 CG16708 FBgn0037315] seq_release:3 mol_weight=75691 cds_boundaries:(3R:1,184,880..1,187,428[-]) aa_length:687 transcript_info:[CG16708-RB seq_release:3] gene_info:[gene symbol:CG16708 FBgn0037315 gene_boundarie [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9VNA6) CG16708-PA [DrosMelano7227.FASTAC.txt]
  • CG16708-PB, isoform B [Drosophila melanogaster]gi|23170446|gb|AAF52040.2| CG16708-PA, isoform A [Drosophila melanogaster]gi|24644205|ref|NP_730923.1| CG16708-PA [Drosophila melanogaster]gi|24644207|ref|NP_649530.2| CG16708-PB [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3R:complement(1184880..1185009,1185070..1185272,1185701..1187431); ID=FBpp0078446; name=CG16708-PA; parent=FBgn0037315,FBtr0078803; dbxref=FlyBase:FBpp0078446,FlyBase_Annotation_IDs:CG16708-PA,GB_protein:AAF52040.2,REFSEQ:NP_730923,GB_pr [fly-100309-contam.fasta]
  • type=protein; loc=3R:complement(1184880..1185009,1185070..1185272,1185701..1187431); ID=FBpp0078447; name=CG16708-PB; parent=FBgn0037315,FBtr0078804; dbxref=FlyBase:FBpp0078447,FlyBase_Annotation_IDs:CG16708-PB,GB_protein:AAN13278.1,REFSEQ:NP_649530,GB_pr [fly-100309-contam.fasta]
  • CG16708-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG16708-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3R:complement(1184880..1185009,1185070..1185272,1185701..1187431); ID=FBpp0078446; name=CG16708-PA; parent=FBgn0037315,FBtr0078803; dbxref=FlyBase:FBpp0078446,FlyBase_Annotation_IDs:CG16708-PA,GB_protein:AAF52040.2,REFSEQ:NP_730923,GB_protein:AAF52040; MD5=74b9e8746490b2f189eef96be563a926; length=687; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3R:complement(1184880..1185009,1185070..1185272,1185701..1187431); ID=FBpp0078447; name=CG16708-PB; parent=FBgn0037315,FBtr0078804; dbxref=FlyBase:FBpp0078447,FlyBase_Annotation_IDs:CG16708-PB,GB_protein:AAN13278.1,REFSEQ:NP_649530,GB_protein:AAN13278; MD5=74b9e8746490b2f189eef96be563a926; length=687; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3R:complement(1184880..1185009,1185070..1185272,1185701..1187431); ID=FBpp0078446; name=CG16708-PA; parent=FBgn0037315,FBtr0078803; dbxref=FlyBase:FBpp0078446,FlyBase_Annotation_IDs:CG16708-PA,GB_protein:AAF52040.2,REFSEQ:NP_730923,GB_protein:AAF52040; MD5=74b9e8746490b2f189eef96be563a926; length=687; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • type=protein; loc=3R:complement(1184880..1185009,1185070..1185272,1185701..1187431); ID=FBpp0078447; name=CG16708-PB; parent=FBgn0037315,FBtr0078804; dbxref=FlyBase:FBpp0078447,FlyBase_Annotation_IDs:CG16708-PB,GB_protein:AAN13278.1,REFSEQ:NP_649530,GB_protein:AAN13278; MD5=74b9e8746490b2f189eef96be563a926; length=687; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • CG16708, isoform A OS=Drosophila melanogaster GN=Cerk PE=2 SV=2 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=3R:complement(1184880..1185009,1185070..1185272,1185701..1187431); ID=FBpp0078446; name=Cerk-PA; parent=FBgn0037315,FBtr0078803; dbxref=FlyBase:FBpp0078446,FlyBase_Annotation_IDs:CG16708-PA,GB_protein:AAF52040.2,REFSEQ:NP_730923,GB_protein:AAF52040,FlyMine:FBpp0078446,modMine:FBpp0078446; MD5=74b9e8746490b2f189eef96be563a926; length=687; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3R:complement(1184880..1185009,1185070..1185272,1185701..1187431); ID=FBpp0078447; name=Cerk-PB; parent=FBgn0037315,FBtr0078804; dbxref=FlyBase:FBpp0078447,FlyBase_Annotation_IDs:CG16708-PB,GB_protein:AAN13278.1,REFSEQ:NP_649530,GB_protein:AAN13278; MD5=74b9e8746490b2f189eef96be563a926; length=687; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3R:complement(join(5359979..5361709,5359348..5359550,5359158..5359287)); ID=FBpp0078446; name=Cerk-PA; parent=FBgn0037315,FBtr0078803; dbxref=FlyBase:FBpp0078446,FlyBase_Annotation_IDs:CG16708-PA,GB_protein:AAF52040.2,REFSEQ:NP_730923,GB_protein:AAF52040,FlyMine:FBpp0078446,modMine:FBpp0078446; MD5=74b9e8746490b2f189eef96be563a926; length=687; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3R:complement(join(5359979..5361709,5359348..5359550,5359158..5359287)); ID=FBpp0078447; name=Cerk-PB; parent=FBgn0037315,FBtr0078804; dbxref=FlyBase:FBpp0078447,FlyBase_Annotation_IDs:CG16708-PB,GB_protein:AAN13278.1,REFSEQ:NP_649530,GB_protein:AAN13278; MD5=74b9e8746490b2f189eef96be563a926; length=687; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3R:complement(join(5359979..5361709,5359348..5359550,5359158..5359287)); ID=FBpp0078446; name=Cerk-PA; parent=FBgn0037315,FBtr0078803; dbxref=FlyBase:FBpp0078446,FlyBase_Annotation_IDs:CG16708-PA,GB_protein:AAF52040.2,REFSEQ:NP_730923,GB_protein:AAF52040,FlyMine:FBpp0078446,modMine:FBpp0078446; MD5=74b9e8746490b2f189eef96be563a926; length=687; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • type=protein; loc=3R:complement(join(5359979..5361709,5359348..5359550,5359158..5359287)); ID=FBpp0078447; name=Cerk-PB; parent=FBgn0037315,FBtr0078804; dbxref=FlyBase:FBpp0078447,FlyBase_Annotation_IDs:CG16708-PB,GB_protein:AAN13278.1,REFSEQ:NP_649530,GB_protein:AAN13278; MD5=74b9e8746490b2f189eef96be563a926; length=687; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Ceramide kinase, isoform A OS=Drosophila melanogaster GN=Cerk PE=2 SV=2 [DROME.fasta.20160308]
  • FBpp0078446 type=protein; loc=3R:complement(join(5359979..5361709,5359348..5359550,5359158..5359287)); ID=FBpp0078446; name=Cerk-PA; parent=FBgn0037315,FBtr0078803; dbxref=FlyBase:FBpp0078446,FlyBase_Annotation_IDs:CG16708-PA,GB_protein:AAF52040.2,REFSEQ:NP_730923,GB_protein:AAF52040,FlyMine:FBpp0078446,modMine:FBpp0078446; MD5=74b9e8746490b2f189eef96be563a926; length=687; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • FBpp0078447 type=protein; loc=3R:complement(join(5359979..5361709,5359348..5359550,5359158..5359287)); ID=FBpp0078447; name=Cerk-PB; parent=FBgn0037315,FBtr0078804; dbxref=FlyBase:FBpp0078447,FlyBase_Annotation_IDs:CG16708-PB,GB_protein:AAN13278.1,REFSEQ:NP_649530,GB_protein:AAN13278; MD5=74b9e8746490b2f189eef96be563a926; length=687; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3R:complement(join(5359979..5361709,5359348..5359550,5359158..5359287)); ID=FBpp0078446; name=Cerk-PA; parent=FBgn0037315,FBtr0078803; dbxref=FlyBase:FBpp0078446,FlyBase_Annotation_IDs:CG16708-PA,GB_protein:AAF52040.2,REFSEQ:NP_730923,GB_protein:AAF52040,UniProt/TrEMBL:Q9VNA6,FlyMine:FBpp0078446,modMine:FBpp0078446; MD5=74b9e8746490b2f189eef96be563a926; length=687; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
  • type=protein; loc=3R:complement(join(5359979..5361709,5359348..5359550,5359158..5359287)); ID=FBpp0078447; name=Cerk-PB; parent=FBgn0037315,FBtr0078804; dbxref=FlyBase:FBpp0078447,FlyBase_Annotation_IDs:CG16708-PB,GB_protein:AAN13278.1,REFSEQ:NP_649530,GB_protein:AAN13278,UniProt/TrEMBL:Q9VNA6; MD5=74b9e8746490b2f189eef96be563a926; length=687; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 687 amino acids

    Gene Ontology:
    Cellular Component: plasma membrane [IDA]
    integral to membrane of membrane fraction [IDA]
    Biological Process: autophagic cell death [IEP]
    salivary gland cell autophagic cell death [IEP]
    activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway [IEA]
    phototransduction [IMP]
    Molecular Function: D-erythro-sphingosine kinase activity [ISS]
    diacylglycerol kinase activity [IEA]
    ceramide kinase activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTQTKQPAGR SSTSAGDFVA PISSTSASKF TPCSASDHNV LLNNFQLKKK SYRVLLHGQQ  60
   61 LVWERLQKIK QSPQGNEAKA PLPPDSPAQP GGICSYGPQS HVLHLDDVVS IRSGDTKASS 120
  121 LKPPSPPGSE RSSGCSGDVA QGKPTSQYLT INYAMRLSKS QTDCNRWELR RLTFFNSDPY 180
  181 IVRQWDQELQ IRLHSSSPTR MRVRRLLVFI NPYGGRKAGA QTYERHVRPI FQLAGVDATC 240
  241 ITTQRANQVK DILLSHDLGV YDAVCCVGGD GTVAEVINGL IFRQMRELGL DEQRPPYIPR 300
  301 PALPVGVIPA GSTDTIAYSM HGTADVRTAA IHVILGQHRG LDVCSVSNGQ SLLRFCASVL 360
  361 SYGYLGDVAA QSENYRWMGP RRYEYSGVKA FLNNRGYDAE LRMLEEPDLL LTTPLEDIPQ 420
  421 SPDSVCSLGE SVPSVCYANC QRCSFASSIQ EQRSSLFIQE ESKEAERNQQ VETEDSHLAA 480
  481 SEAALLRPRP RPGNLRLPTG SISSMRNLGN DQWKVVRGNF FMICGANITC ACARSPNGIS 540
  541 RYSHLGDGCL DLILVKKTSL LNNVRFLLNT AGRSGDIRNL PFVEVYRTRE FRFRTFSASE 600
  601 EDYSLAGSCQ PITPPEEMTA HSSSTEFSSW NCDGEVVTDL DITMRSHCQL IEVFMRGPHS 660
  661 YSKPLKGGTT PTTPASSSDN VYCCCKD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..202] MSA 4.209986 View MSA. No confident structure predictions are available.
    2 View Details [203..510] PSI-BLAST 33.154902 No description for 2jgrA was found.
    3 View Details [511..687] FFAS03 2.01 No description for 2bonA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • catalytic activity
    		•  0.33446102778142 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.67

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle