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Protein Overview: CG5976-PB

General Information:
Name(s) found: CG5976-PB / FBpp0077857 [FlyBase]
Description(s) found:
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  • gi|28574640|ref|NP_788550.1| CG5976, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|27819791|gb|AAO24944.1| RE61650p [Drosophila melanogaster] [NCBI NR]
  • gi|23094167|gb|AAF51610.2| CG5976, isoform B [Drosophila melanogaster] [NCBI NR]
  • This gene is referred to in FlyBase by the symbol Dmel\CG5976 (CG5976, FBgn0036999). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:20467566..20470103. It has the cytological map location 77C4. Based on sequence similarity, it is predicted to have molecular function</span>: glutaminyl-peptide cyclotransferase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: proteolysis. 6 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • >CG5976-PB translation from_gene[CG5976 CG5976 FBgn0052426] seq_release:3 mol_weight=40839 cds_boundaries:(3L:20,393,065..20,395,047[+]) aa_length:354 transcript_info:[CG5976-RB seq_release:3] gene_info:[gene symbol:CG5976 synonyms:[CG32426 CG5969] FBg [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q86PD7) RE61650p (CG5976-PB) [DrosMelano7227.FASTAC.txt]
  • CG5976-PB, isoform B [Drosophila melanogaster]gi|27819791|gb|AAO24944.1| RE61650p [Drosophila melanogaster]gi|28574640|ref|NP_788550.1| CG5976-PB [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3L:join(20467627..20467743,20468665..20469612); ID=FBpp0077857; name=CG5976-PB; parent=FBgn0036999,FBtr0078199; dbxref=FlyBase:FBpp0077857,FlyBase_Annotation_IDs:CG5976-PB,GB_protein:AAF51610.2,REFSEQ:NP_788550,GB_protein:AAF51610; MD5=b [fly-100309-contam.fasta]
  • RE61650p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG5976-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3L:join(20467627..20467743,20468665..20469612); ID=FBpp0077857; name=CG5976-PB; parent=FBgn0036999,FBtr0078199; dbxref=FlyBase:FBpp0077857,FlyBase_Annotation_IDs:CG5976-PB,GB_protein:AAF51610.2,REFSEQ:NP_788550,GB_protein:AAF51610; MD5=b69d5809b192e8df35fab146f0f23764; length=354; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3L:join(20467627..20467743,20468665..20469612); ID=FBpp0077857; name=CG5976-PB; parent=FBgn0036999,FBtr0078199; dbxref=FlyBase:FBpp0077857,FlyBase_Annotation_IDs:CG5976-PB,GB_protein:AAF51610.2,REFSEQ:NP_788550,GB_protein:AAF51610; MD5=b69d5809b192e8df35fab146f0f23764; length=354; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • CG5976, isoform B OS=Drosophila melanogaster GN=CG5976 PE=1 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=3L:join(20467627..20467743,20468665..20469612); ID=FBpp0077857; name=isoQC-PB; parent=FBgn0036999,FBtr0078199; dbxref=FlyBase:FBpp0077857,FlyBase_Annotation_IDs:CG5976-PB,GB_protein:AAF51610.2,REFSEQ:NP_788550,GB_protein:AAF51610,FlyMine:FBpp0077857,modMine:FBpp0077857; MD5=b69d5809b192e8df35fab146f0f23764; length=354; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • CG5976, isoform B OS=Drosophila melanogaster GN=isoQC PE=2 SV=1 [UniProt_D_Melanogaster_07132012_07-13-2012_reversed.fasta]
  • type=protein; loc=3L:join(20474527..20474643,20475565..20476512); ID=FBpp0077857; name=isoQC-PB; parent=FBgn0036999,FBtr0078199; dbxref=FlyBase:FBpp0077857,FlyBase_Annotation_IDs:CG5976-PB,GB_protein:AAF51610.2,REFSEQ:NP_788550,GB_protein:AAF51610,FlyMine:FBpp0077857,modMine:FBpp0077857; MD5=b69d5809b192e8df35fab146f0f23764; length=354; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3L:join(20474527..20474643,20475565..20476512); ID=FBpp0077857; name=isoQC-PB; parent=FBgn0036999,FBtr0078199; dbxref=FlyBase:FBpp0077857,FlyBase_Annotation_IDs:CG5976-PB,GB_protein:AAF51610.2,REFSEQ:NP_788550,GB_protein:AAF51610,FlyMine:FBpp0077857,modMine:FBpp0077857; MD5=b69d5809b192e8df35fab146f0f23764; length=354; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Iso glutaminyl cyclase, isoform B OS=Drosophila melanogaster GN=isoQC PE=1 SV=1 [DROME.fasta.20160308]
  • FBpp0077857 type=protein; loc=3L:join(20474527..20474643,20475565..20476512); ID=FBpp0077857; name=isoQC-PB; parent=FBgn0036999,FBtr0078199; dbxref=FlyBase:FBpp0077857,FlyBase_Annotation_IDs:CG5976-PB,GB_protein:AAF51610.2,REFSEQ:NP_788550,GB_protein:AAF51610,FlyMine:FBpp0077857,modMine:FBpp0077857; MD5=b69d5809b192e8df35fab146f0f23764; length=354; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3L:join(20474527..20474643,20475565..20476512); ID=FBpp0077857; name=isoQC-PB; parent=FBgn0036999,FBtr0078199; dbxref=FlyBase:FBpp0077857,FlyBase_Annotation_IDs:CG5976-PB,GB_protein:AAF51610.2,REFSEQ:NP_788550,GB_protein:AAF51610,UniProt/TrEMBL:Q86PD7,FlyMine:FBpp0077857,modMine:FBpp0077857; MD5=b69d5809b192e8df35fab146f0f23764; length=354; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 354 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: proteolysis [IEA]
    Molecular Function: glutaminyl-peptide cyclotransferase activity [ISS]
    peptidase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLLLRNYSL MEAVKRLLPR PRKKIYNLGA CFELVDIPKI SYNPSELSEP RFLEYSNLSD  60
   61 KLHLREAIDK ILIPRVVGTT NHSIVREYIV QSLRDLDWDV EVNSFHDHAP IKGKLHFHNI 120
  121 IATLNPNAER YLVLSCHYDS KYMPGVEFLG ATDSAVPCAM LLNLAQVLQE QLKPLKKSKL 180
  181 SLMLLFFDGE EAFEEWGPKD SIYGARHLAK KWHHEGKLDR IDMLVLLDLL GAPDPAFYSF 240
  241 FENTESWYMR IQSVETRLAK LQLLERYASS GVAQRDPTRY FQSQAMRSSF IEDDHIPFLR 300
  301 RNVPILHLIP VPFPSVWHTP DDNASVIDYA TTDNLALIIR LFALEYLLAG TEAK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle