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Protein Overview: Psn-PA, FBpp0305666

General Information:
Name(s) found: FBpp0305666 [FlyBase]
Psn-PA / FBpp0077850 [FlyBase]
Description(s) found:
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  • gi|7296308|gb|AAF51598.1| presenilin, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|6174933|sp|O02194.2|PSN_DROME RecName: Full=Presenilin homolog; Short=DmPS; AltName: Full=dPS [NCBI NR]
  • gi|5817328|gb|AAD52707.1|AF093402_1 presenilin a2 [Drosophila melanogaster] [NCBI NR]
  • gi|4102871|gb|AAD01610.1| presenilin; PS-D [Drosophila melanogaster] [NCBI NR]
  • gi|3462890|gb|AAC33129.1| presenilin long form [Drosophila melanogaster] [NCBI NR]
  • gi|2194201|gb|AAB61139.1| presenilin homolog [Drosophila melanogaster] [NCBI NR]
  • gi|17737687|ref|NP_524184.1| presenilin, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|16769290|gb|AAL28864.1| LD23505p [Drosophila melanogaster] [NCBI NR]
  • Presenilin homolog OS=Drosophila melanogaster GN=Psn PE=1 SV=2 [Swiss-Prot]
  • type=protein; loc=3L:join(20425942..20426106,20426172..20426410,20426478..20426687,20426741..20426961,20427034..20427132,20427187..20427444,20427648..20427812,20427881..20428149); ID=FBpp0305666; name=Psn-PE; parent=FBgn0019947,FBtr0333479; dbxref=REFSEQ:NP_001262111,GB_protein:AGB94804,FlyBase:FBpp0305666,FlyBase_Annotation_IDs:CG18803-PE; MD5=893cf5f37d29f252f17e5859073bd085; length=541; release=r5.56; species=Dmel; [FlyBase]
  • The gene Presenilin is referred to in FlyBase by the symbol Dmel\Psn (CG18803, FBgn0019947). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:20425568..20428256. It has the cytological map location 77C3. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: Notch receptor processing; cell-cell adhesion; wing disc dorsal/ventral pattern formation; Notch signaling pathway; cytoskeleton organization. 106 alleles are reported. The phenotypes of these alleles are annotated with 30 unique terms, many of which group under: adult segment; external compound sense organ; peripheral nervous system; adult mesothoracic segment; nervous system; embryonic nervous system; imaginal precursor; organ system; primordium; larval thorax. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
  • >CG18803-PA translation from_gene[CG18803 Psn FBgn0019947] seq_release:3 mol_weight=59305 cds_boundaries:(3L:20,351,380..20,353,584[+]) aa_length:541 transcript_info:[CG18803-RA seq_release:3] gene_info:[gene symbol:Psn synonyms:[CG5868] FBgn0019947 ge [hmr_yeast5_DM3-1_pombe.fasta]
  • (O02194) Presenilin homolog (dPS) (DmPS) [DrosMelano7227.FASTAC.txt]
  • (AE003591) CG18803 gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG18803-PA, isoform A [Drosophila melanogaster]gi|16769290|gb|AAL28864.1| LD23505p [Drosophila melanogaster]gi|5817328|gb|AAD52707.1| presenilin a2 [Drosophila melanogaster]gi|17737687|ref|NP_524184.1| CG18803-PA [Drosophila melanogaster]gi|3462890|gb [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3L:join(20425942..20426106,20426172..20426410,20426478..20426687,20426741..20426961,20427034..20427132,20427187..20427444,20427648..20427812,20427881..20428149); ID=FBpp0077850; name=Psn-PA; parent=FBgn0019947,FBtr0078192; dbxref=FlyBase [fly-100309-contam.fasta]
  • presenilin homolog [Drosophila melanogaster] [nr-271106-contam.fasta]
  • presenilin a2 [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Presenilin CG18803-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta]
  • presenilin long form [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG18803-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta]
  • presenilin; PS-D [Drosophila melanogaster] [nr-271106-contam.fasta]
  • LD23505p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Presenilin homolog (dPS) (DmPS) [nr-271106-contam.fasta]
  • type=protein; loc=3L:join(20425942..20426106,20426172..20426410,20426478..20426687,20426741..20426961,20427034..20427132,20427187..20427444,20427648..20427812,20427881..20428149); ID=FBpp0077850; name=Psn-PA; parent=FBgn0019947,FBtr0078192; dbxref=FlyBase:FBpp0077850,FlyBase_Annotation_IDs:CG18803-PA,GB_protein:AAF51598.1,REFSEQ:NP_524184,GB_protein:AAF51598; MD5=893cf5f37d29f252f17e5859073bd085; length=541; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3L:join(20425942..20426106,20426172..20426410,20426478..20426687,20426741..20426961,20427034..20427132,20427187..20427444,20427648..20427812,20427881..20428149); ID=FBpp0077850; name=Psn-PA; parent=FBgn0019947,FBtr0078192; dbxref=FlyBase:FBpp0077850,FlyBase_Annotation_IDs:CG18803-PA,GB_protein:AAF51598.1,REFSEQ:NP_524184,GB_protein:AAF51598; MD5=893cf5f37d29f252f17e5859073bd085; length=541; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • type=protein; loc=3L:join(20425942..20426106,20426172..20426410,20426478..20426687,20426741..20426961,20427034..20427132,20427187..20427444,20427648..20427812,20427881..20428149); ID=FBpp0077850; name=Psn-PA; parent=FBgn0019947,FBtr0078192; dbxref=FlyBase:FBpp0077850,FlyBase_Annotation_IDs:CG18803-PA,GB_protein:AAF51598.1,REFSEQ:NP_524184,GB_protein:AAF51598,FlyMine:FBpp0077850,modMine:FBpp0077850; MD5=893cf5f37d29f252f17e5859073bd085; length=541; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3L:join(20425942..20426106,20426172..20426410,20426478..20426687,20426741..20426961,20427034..20427132,20427187..20427444,20427648..20427812,20427881..20428149); ID=FBpp0305666; name=Psn-PE; parent=FBgn0019947,FBtr0333479; dbxref=FlyBase:FBpp0305666,FlyBase_Annotation_IDs:CG18803-PE; MD5=893cf5f37d29f252f17e5859073bd085; length=541; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3L:join(20432842..20433006,20433072..20433310,20433378..20433587,20433641..20433861,20433934..20434032,20434087..20434344,20434548..20434712,20434781..20435049); ID=FBpp0077850; name=Psn-PA; parent=FBgn0019947,FBtr0078192; dbxref=FlyBase:FBpp0077850,FlyBase_Annotation_IDs:CG18803-PA,GB_protein:AAF51598.1,REFSEQ:NP_524184,GB_protein:AAF51598,FlyMine:FBpp0077850,modMine:FBpp0077850; MD5=893cf5f37d29f252f17e5859073bd085; length=541; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3L:join(20432842..20433006,20433072..20433310,20433378..20433587,20433641..20433861,20433934..20434032,20434087..20434344,20434548..20434712,20434781..20435049); ID=FBpp0305666; name=Psn-PE; parent=FBgn0019947,FBtr0333479; dbxref=REFSEQ:NP_001262111,GB_protein:AGB94804,FlyBase:FBpp0305666,FlyBase_Annotation_IDs:CG18803-PE; MD5=893cf5f37d29f252f17e5859073bd085; length=541; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3L:join(20432842..20433006,20433072..20433310,20433378..20433587,20433641..20433861,20433934..20434032,20434087..20434344,20434548..20434712,20434781..20435049); ID=FBpp0077850; name=Psn-PA; parent=FBgn0019947,FBtr0078192; dbxref=FlyBase:FBpp0077850,FlyBase_Annotation_IDs:CG18803-PA,GB_protein:AAF51598.1,REFSEQ:NP_524184,GB_protein:AAF51598,FlyMine:FBpp0077850,modMine:FBpp0077850; MD5=893cf5f37d29f252f17e5859073bd085; length=541; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • type=protein; loc=3L:join(20432842..20433006,20433072..20433310,20433378..20433587,20433641..20433861,20433934..20434032,20434087..20434344,20434548..20434712,20434781..20435049); ID=FBpp0305666; name=Psn-PE; parent=FBgn0019947,FBtr0333479; dbxref=REFSEQ:NP_001262111,GB_protein:AGB94804,FlyBase:FBpp0305666,FlyBase_Annotation_IDs:CG18803-PE; MD5=893cf5f37d29f252f17e5859073bd085; length=541; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of O02194, Presenilin OS=Drosophila melanogaster GN=Psn PE=1 SV=1 [DROME.fasta.20160308]
  • FBpp0077850 type=protein; loc=3L:join(20432842..20433006,20433072..20433310,20433378..20433587,20433641..20433861,20433934..20434032,20434087..20434344,20434548..20434712,20434781..20435049); ID=FBpp0077850; name=Psn-PA; parent=FBgn0019947,FBtr0078192; dbxref=FlyBase:FBpp0077850,FlyBase_Annotation_IDs:CG18803-PA,GB_protein:AAF51598.1,REFSEQ:NP_524184,GB_protein:AAF51598,FlyMine:FBpp0077850,modMine:FBpp0077850; MD5=893cf5f37d29f252f17e5859073bd085; length=541; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • FBpp0305666 type=protein; loc=3L:join(20432842..20433006,20433072..20433310,20433378..20433587,20433641..20433861,20433934..20434032,20434087..20434344,20434548..20434712,20434781..20435049); ID=FBpp0305666; name=Psn-PE; parent=FBgn0019947,FBtr0333479; dbxref=REFSEQ:NP_001262111,GB_protein:AGB94804,FlyBase:FBpp0305666,FlyBase_Annotation_IDs:CG18803-PE; MD5=893cf5f37d29f252f17e5859073bd085; length=541; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3L:join(20432842..20433006,20433072..20433310,20433378..20433587,20433641..20433861,20433934..20434032,20434087..20434344,20434548..20434712,20434781..20435049); ID=FBpp0077850; name=Psn-PA; parent=FBgn0284421,FBtr0078192; dbxref=FlyBase:FBpp0077850,FlyBase_Annotation_IDs:CG18803-PA,GB_protein:AAF51598.1,REFSEQ:NP_524184,GB_protein:AAF51598,UniProt/Swiss-Prot:O02194,FlyMine:FBpp0077850,modMine:FBpp0077850; MD5=893cf5f37d29f252f17e5859073bd085; length=541; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
  • type=protein; loc=3L:join(20432842..20433006,20433072..20433310,20433378..20433587,20433641..20433861,20433934..20434032,20434087..20434344,20434548..20434712,20434781..20435049); ID=FBpp0305666; name=Psn-PE; parent=FBgn0284421,FBtr0333479; dbxref=REFSEQ:NP_001262111,GB_protein:AGB94804,FlyBase:FBpp0305666,FlyBase_Annotation_IDs:CG18803-PE,UniProt/Swiss-Prot:O02194; MD5=893cf5f37d29f252f17e5859073bd085; length=541; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 541 amino acids

    Gene Ontology:
    Cellular Component: integral to plasma membrane [IDA]
    cytoplasm [IDA]
    cell cortex [IDA]
    apical plasma membrane [IDA]
    Biological Process: cell-cell adhesion [IMP]
    intracellular signaling pathway [IEA]
    Notch signaling pathway [IMP]
    cytoskeleton organization [IMP]
    membrane protein ectodomain proteolysis [TAS]
    Notch receptor processing [IMP][TAS]
    wing disc dorsal/ventral pattern formation [IMP]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAVNLQASC SSGLASEDDA NVGSQIGAAE RLERPPRRQQ QRNNYGSSNQ DQPDAAILAV  60
   61 PNVVMREPCG SRPSRLTGGG GGSGGPPTNE MEEEQGLKYG AQHVIKLFVP VSLCMLVVVA 120
  121 TINSISFYNS TDVYLLYTPF HEQSPEPSVK FWSALANSLI LMSVVVVMTF LLIVLYKKRC 180
  181 YRIIHGWLIL SSFMLLFIFT YLYLEELLRA YNIPMDYPTA LLIMWNFGVV GMMSIHWQGP 240
  241 LRLQQGYLIF VAALMALVFI KYLPEWTAWA VLAAISIWDL IAVLSPRGPL RILVETAQER 300
  301 NEQIFPALIY SSTVVYALVN TVTPQQSQAT ASSSPSSSNS TTTTRATQNS LASPEAAAAS 360
  361 GQRTGNSHPR QNQRDDGSVL ATEGMPLVTF KSNLRGNAEA AGFTQEWSAN LSERVARRQI 420
  421 EVQSTQSGNA QRSNEYRTVT APDQNHPDGQ EERGIKLGLG DFIFYSVLVG KASSYGDWTT 480
  481 TIACFVAILI GLCLTLLLLA IWRKALPALP ISITFGLIFC FATSAVVKPF MEDLSAKQVF 540
  541 I

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle