Protein Overview: Mi-2-PA, Mi-2-PC

General Information:
Name(s) found:	Mi-2-PC / FBpp0291256 [FlyBase] Mi-2-PA / FBpp0074688 [FlyBase]
Description(s) found: Found 28 descriptions. SHOW ALL	The gene Mi-2 is referred to in FlyBase by the symbol Dmel\Mi-2 (CG8103, FBgn0013591). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:19875151..19903309. It has the cytological map location 76D3-76D4. There is experimental evidence that it has the molecular function</span>: transcription repressor activity; nucleosome binding; ATPase activity, coupled; ATPase activity; DNA binding. There is experimental evidence that it is involved in the biological process</span>: dendrite morphogenesis; nucleosome mobilization; muscle organ development. 55 alleles are reported. The phenotype of these alleles is annotated with: dendrite. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase] The gene Mi-2 is referred to in FlyBase by the symbol Dmel\Mi-2 (CG8103, FBgn0013591). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:19875151..19903309. It has the cytological map location 76D3-76D4. There is experimental evidence that it has the molecular function</span>: transcription repressor activity; nucleosome binding; ATPase activity, coupled; ATPase activity; DNA binding. There is experimental evidence that it is involved in the biological process</span>: dendrite morphogenesis; nucleosome mobilization; muscle organ development. 55 alleles are reported. The phenotype of these alleles is annotated with: dendrite. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	1982 amino acids
Gene Ontology:
Cellular Component:	nucleus [ISS][NAS] polytene chromosome [IDA] NuRD complex [ISS][TAS] chromatin [IEA]
Biological Process:	muscle organ development [IMP] chromatin assembly or disassembly [ISS] regulation of transcription [IEA] nucleosome mobilization [IDA] dendrite morphogenesis [IMP]
Molecular Function:	ATPase activity [IDA][NAS] zinc ion binding [IEA] nucleosome binding [IDA] ATP-dependent helicase activity [IEA] helicase activity [ISS] chromatin binding [ISS] ATP-dependent DNA helicase activity [ISS] ATPase activity, coupled [IDA] DNA binding [IDA] ATP binding [IEA] DNA helicase activity [ISS] protein binding [IEA] transcription repressor activity [IGI]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASEEENDDN FQEEEEAQED NAPAAELSND SDAPLKPNND EDDDYDPEDS RRKKKGKKRK  60
   61 TRKGEEKGRK KKKRKKNESE EDSDFVQHDE EVEYPSTSKR GRKRKEEKQA AKEKESASSG 120
  121 MPSVEDVCSA FSVCNVEIEY SEEELQSLTT YKAFMHHVRP ILQKENPKIA APKLVMLVAA 180
  181 KWREFCESNP HIQQEGGAAG SGGSAGQARS VTGDEPEEPR SSRSSRNEKP DDIYEEAVEE 240
  241 EEEEEEEEKK PRRKRSGRGK KGRRPSGKVP TLKIKLLGKR KRDSSDEEQD ASGASERDSD 300
  301 LEFERMLQKS DDSADEKEAP VSSKADNSAP AAQDDGSGAP VVRKKAKTKI GNKFKKKNKL 360
  361 KKTKNFPEGE DGEHEHQDYC EVCQQGGEII LCDTCPRAYH LVCLEPELDE PPEGKWSCPH 420
  421 CEADGGAAEE EDDDEHQEFC RVCKDGGELL CCDSCPSAYH TFCLNPPLDT IPDGDWRCPR 480
  481 CSCPPLTGKA EKIITWRWAQ RSNDDGPSTS KGSKNSNSRV REYFIKWHNM SYWHCEWVPE 540
  541 VQLDVHHPLM IRSFQRKYDM EEPPKFEESL DEADTRYKRI QRHKDKVGMK ANDDAEVLEE 600
  601 RFYKNGVKPE WLIVQRVINH RTARDGSTMY LVKWRELPYD KSTWEEEGDD IQGLRQAIDY 660
  661 YQDLRAVCTS ETTQSRSKKS KKGRKSKLKV EDDEDRPVKH YTPPPEKPTT DLKKKYEDQP 720
  721 AFLEGTGMQL HPYQIEGINW LRYSWGQGID TILADEMGLG KTIQTVTFLY SLYKEGHCRG 780
  781 PFLVAVPLST LVNWEREFEL WAPDFYCITY IGDKDSRAVI RENELSFEEG AIRGSKVSRL 840
  841 RTTQYKFNVL LTSYELISMD AACLGSIDWA VLVVDEAHRL KSNQSKFFRI LNSYTIAYKL 900
  901 LLTGTPLQNN LEELFHLLNF LSRDKFNDLQ AFQGEFADVS KEEQVKRLHE MLGPHMLRRL 960
  961 KTDVLKNMPS KSEFIVRVEL SAMQKKFYKF ILTKNYEALN SKSGGGSCSL INIMMDLKKC1020
 1021 CNHPYLFPSA AEEATTAAGG LYEINSLTKA AGKLVLLSKM LKQLKAQNHR VLIFSQMTKM1080
 1081 LDILEDFLEG EQYKYERIDG GITGTLRQEA IDRFNAPGAQ QFVFLLSTRA GGLGINLATA1140
 1141 DTVIIYDSDW NPHNDIQAFS RAHRIGQANK VMIYRFVTRN SVEERVTQVA KRKMMLTHLV1200
 1201 VRPGMGGKGA NFTKQELDDI LRFGTEDLFK EDDKEEAIHY DDKAVAELLD RTNRGIEEKE1260
 1261 SWANEYLSSF KVASYATKEE EEEEETEIIK QDAENSDPAY WVKLLRHHYE QHQEDVGRSL1320
 1321 GKGKRVRKQV NYTDGGVVAA DTTRDDSNWQ DNGSEYNSEY SAGSDEDGGD DDFDDQNGAE1380
 1381 RKAKRRLERR DDRPLPPLLA RVGGNIEVLG FNARQRKSFL NAIMRYGMPP QDAFNSQWLV1440
 1441 RDLRGKSERN FKAYVSLFMR HLCEPGADNA ETFADGVPRE GLSRQHVLTR IGVMSLIRKK1500
 1501 VQEFEHINGY YSMPELILKP CEPVRSALKQ DVAALEAPPT GGNVDKSATT SNSVTPATSA1560
 1561 APSPAPASEK GEDKDKDSEK EKDKTSAEKS EVKQEQEAEE DKKPGDVKQE NPVEEAAGDT1620
 1621 KPSDAEVKTE VAKTEPKEET KDPEVKEEPK TEEKEKEKVD DKKPIPPTTV IDDDDDDVMI1680
 1681 VKEDGELEKP SASSPKDQKA VAAATSAATG ATGKGAEDSL EVLKRKFMFN IADGGFTELH1740
 1741 TLWLNEEKAA VPGREYEIWH RRHDYWLLAG IVTHGYGRWQ DIQNDIRFAI INEPFKMDVG1800
 1801 KGNFLEIKNK FLARRFKLLE QALVIEEQLR RAAYLNLAQD PSHPAMSLNA RFAEVECLAE1860
 1861 SHQHLSKESL AGNKPANAVL HKVLNQLEEL LSDMKSDVSR LPATLARIPP VAQRLQMSER1920
 1921 SILSRLAATA GNASNAAQLM AQFPAGFQGT TLPAFTSGPA GNFANFRPQF SVPGQLSNNS1980
 1981 GV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Protein Overview: Mi-2-PA, Mi-2-PC

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: