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Protein Overview: Pdh-PA

General Information:
Name(s) found: Pdh-PA / FBpp0075184 [FlyBase]
Description(s) found:
Found 23 descriptions.
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  • The gene Photoreceptor dehydrogenase is referred to in FlyBase by the symbol Dmel\Pdh (CG4899, FBgn0011693). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:16346327..16347397. It has the cytological map location 72E2. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: binding; alcohol dehydrogenase (NAD) activity. There is experimental evidence that it is involved in the biological process</span>: phagocytosis, engulfment. 6 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 278 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: phagocytosis, engulfment [IMP]
    oxidation reduction [IEA]
    Molecular Function: alcohol dehydrogenase (NAD) activity [IEA]
    binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKPQGIPPTT TRISQTKMSF RGKNAVVTGG AGGIGLQVSK QLLAAGAAKV AIIDLQDNLE  60
   61 EFVKLRAAHP TQSVMIIKMD VANKKGVEAT YEEIAKTFGN IDIVVNVAGI FNDKDVQRTL 120
  121 LVNLGGIINS TLSALPYMGK DNGGKGGIVV NMSSVVGLDP MFIIPVYGAT KAGIINFTRC 180
  181 LANEKYYQRS GIKFVTVCPG ATMTDMFTNF TEKIIFPETS DETYRILDRL NKQSAADVSR 240
  241 CILNVLEKDK NGAVYVIEGK RVYPLEIKPQ WTGKEQAL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..278] PSI-BLAST 45.522879 No description for 2gdzA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • NAD or NADH binding
    		•  2.13234420851832 bayes_pls_golite062009
  • catalytic activity
    		•  1.79741889688267 bayes_pls_golite062009
  • alcohol dehydrogenase activity, zinc-dependent
    		•  1.54163865723354 bayes_pls_golite062009
  • ethanol binding
    		•  1.50520365612357 bayes_pls_golite062009
  • retinol binding
    		•  1.31161238631275 bayes_pls_golite062009
  • fatty acid synthase activity
    		•  1.23679054027553 bayes_pls_golite062009
  • alcohol binding
    		•  1.22695269806324 bayes_pls_golite062009
  • binding
    		•  0.982999356179965 bayes_pls_golite062009
  • oxidoreductase activity
    		•  0.9367410227151 bayes_pls_golite062009
  • 3-oxoacyl-[acyl-carrier-protein] reductase activity
    		•  0.604742541607263 bayes_pls_golite062009
  • NADPH:quinone reductase activity
    		•  0.520319547841251 bayes_pls_golite062009
  • all-trans retinal binding
    		•  0.445128389050035 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  0.418775403210681 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  0.32207755075663 bayes_pls_golite062009
  • DNA binding
    		•  0.302492036575815 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.177044638410302 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.100470710829263 bayes_pls_golite062009
  • benzaldehyde dehydrogenase activity
    		•  0.0870360798161197 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.72

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle