Protein Overview: brm-PB, brm-PA

General Information:
Name(s) found:	brm-PB / FBpp0075281 [FlyBase] brm-PA / FBpp0075280 [FlyBase]
Description(s) found: Found 36 descriptions. SHOW ALL	The gene brahma is referred to in FlyBase by the symbol Dmel\brm (CG5942, FBgn0000212). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:15963182..15975969. It has the cytological map location 72C1. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: imaginal disc-derived wing vein specification; muscle organ development; axonogenesis; dendrite morphogenesis; neuron development; phagocytosis, engulfment. 52 alleles are reported. The phenotypes of these alleles are annotated with 19 unique terms, many of which group under: adult segment; peripheral nervous system; nervous system; adult mesothoracic segment; organ system; external compound sense organ; cell projection; thoracic segment; neuron projection; embryonic/larval hemocoel; eo support cell; multidendritic neuron; axon. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase] The gene brahma is referred to in FlyBase by the symbol Dmel\brm (CG5942, FBgn0000212). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:15963182..15975969. It has the cytological map location 72C1. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: imaginal disc-derived wing vein specification; muscle organ development; axonogenesis; dendrite morphogenesis; neuron development; phagocytosis, engulfment. 52 alleles are reported. The phenotypes of these alleles are annotated with 19 unique terms, many of which group under: adult segment; peripheral nervous system; nervous system; adult mesothoracic segment; organ system; external compound sense organ; cell projection; thoracic segment; neuron projection; embryonic/larval hemocoel; eo support cell; multidendritic neuron; axon. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	1638 amino acids
Gene Ontology:
Cellular Component:	nucleus [NAS] brahma complex [IDA][TAS] chromatin remodeling complex [ISS]
Biological Process:	muscle organ development [IMP] phagocytosis, engulfment [IMP] hemocyte proliferation [TAS] oogenesis [TAS] axonogenesis [IMP] imaginal disc-derived wing vein specification [IMP] neuron development [IMP] chromatin-mediated maintenance of transcription [NAS] regulation of transcription [IEA] dendrite morphogenesis [IMP]
Molecular Function:	ATP binding [IEA] DNA binding [IEA] DNA-dependent ATPase activity [NAS] protein binding [IPI] transcription coactivator activity [ISS][NAS] general RNA polymerase II transcription factor activity [ISS] helicase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASPSPANSP MPPPQAPSPM APPSQSPAPS PHSPYPHQQP GPLQGPPPPG HPGAYGHPMQ  60
   61 HGPPGQGPPG HHMPPHHQGM IFSKGPHMGM QMPPTGPNMS PYQTHGMPPN APTQPCIVSP 120
  121 GGPPGGPPPP ERSSQENLHA LQRAIDSMEE KGLQEDPRYS QLLAMRATSK HQHLNGNQVN 180
  181 LLRTQITAYR LLARNKPISM QMQQALQAAQ QQPPPGPPIG PPGAPGGPPP GSQHAGQPPV 240
  241 PPQQQQQPPP SAGTPPQCST PPASNPYGPP VPGQKMQVAP PPPHMQQGQP LPPQPPQVGG 300
  301 PPPIQQQQPP QQQQQQSQPP PPEPHQHQLP NGGKPLSMGP SGGQPLIPSS PMQPQVRGTL 360
  361 PGMPPGSQVP QPGGGPQRQV PPAGMPMPKP NRITTVAKPV GLDPITLLQE RENRIAARIS 420
  421 LRMQELQRLP ATMSEDLRLQ AAIELRALRV LNFQRQLRME FVQCTRRDTT LETALNIKLY 480
  481 KRTKRQGLRE ARATEKLEKQ QKLEAERKRR QKHLEFLAAV LQHGKDLREF HRNNKAQLAR 540
  541 MNKAVMNHHA NAEREQKKEQ ERIEKERMRR LMAEDEEGYR KLIDQKKDKR LAFLLSQTDE 600
  601 YISNLTQMVK QHKDDQMKKK EEEGKRLIQF KKELLMSGEY IGIDEGSIVA DMRVHVVEQC 660
  661 TGKKLTGDDA PMLKHLHRWL NMHPGWDWID DEEDSCGSND DHKPKVEEQP TATEDATDKA 720
  721 QATGNDEDAK DLITKAKVED DEYRTEEQTY YSIAHTIHEK VVEQASIMVN GTLKEYQIKG 780
  781 LEWLVSLYNN NLNGILADEM GLGKTIQTIS LVTYLMDRKK VMGPYLIIVP LSTLPNWVLE 840
  841 FEKWAPAVGV VSYKGSPQGR RLLQNQMRAT KFNVLLTTYE YVIKDKAVLA KIQWKYMIID 900
  901 EGHRMKNHHC KLTQVLNTHY IAPYRLLLTG TPLQNKLPEL WALLNFLLPS IFKSCSTFEQ 960
  961 WFNAPFATTG EKVELNEEET ILIIRRLHKV LRPFLLRRLK KEVEHQLPDK VEYIIKCDMS1020
 1021 ALQRVLYKHM QSKGVLLTDG SEKGKHGKGG AKALMNTIVQ LRKLCNHPFM FQHIEEKYCD1080
 1081 HTGGHGVVSG PDLYRVSGKF ELLDRILPKL KATNHRVLLF CQMTQCMTII EDYLGWRQFG1140
 1141 YLRLDGTTKA EDRGELLRKF NAKGSDVFVF LLSTRAGGLG LNLQTADTVV IFDSDWNPHQ1200
 1201 DLQAQDRAHR IGQRNEVRVL RLMTVNSVEE RILAAARYKL NMDEKVIQAG MFDQKSTGSE1260
 1261 RQQFLQTILH QDDNEEEEEN EVPDDEMINM MIARSEEEIE IFKRMDAERK KEDEEIHPGR1320
 1321 ERLIDESELP DWLTKDDDEV ERFHYQYDED TILGRGSRQR KEVDYTDSLT EKEWLKAIDD1380
 1381 GAEFDEEEEE DDSKRKRRKR KNRKEESDDD SLILKRRRRQ NLDKRSKKQM HKIMSAVIKH1440
 1441 NQDGRTLSEP FMKLPSRQRL PDYYEIIKRP VDIKKILQRI EDCKYADLNE LEKDFMQLCQ1500
 1501 NAQIYNEEAS LIYLDSIALQ KVFVGARQRI TAAADAAAVA AGDNTGEAHG NGGSDNSDND1560
 1561 DDDGGDDGSD DEEIATTSAA AVKMKLKLNK SLASAPATPT QSSSNVSSGA ATTSKKQTRR1620
 1621 KRSQKKYTIS DDDDDDMD

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: brm-PB, brm-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: