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Protein Overview: Tom-PA

General Information:
Name(s) found: Tom-PA / FBpp0075373 [FlyBase]
Description(s) found:
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  • gi|7294345|gb|AAF49694.1| twin of m4 [Drosophila melanogaster] [NCBI NR]
  • gi|6601392|gb|AAF18973.1|AF175684_1 BARBU [Drosophila melanogaster] [NCBI NR]
  • gi|6540584|gb|AAF16404.1|U13067_1 Twin of m4 [Drosophila melanogaster] [NCBI NR]
  • gi|24664355|ref|NP_524073.2| twin of m4 [Drosophila melanogaster] [NCBI NR]
  • gi|16648272|gb|AAL25401.1| LD05688p [Drosophila melanogaster] [NCBI NR]
  • The gene Twin of m4 is referred to in FlyBase by the symbol Dmel\Tom (CG5185, FBgn0026320). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:14962447..14963417. It has the cytological map location 71A3. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: sensory organ precursor cell fate determination; sensory organ development; establishment of planar polarity; Notch signaling pathway; cell fate specification. 12 alleles are reported. The phenotypes of these alleles are annotated with 18 unique terms, many of which group under: peripheral nervous system; nervous system; external compound sense organ; organ system; adult segment; adult mesothoracic segment; compound cell cluster organ; embryonic head; embryonic/larval hypodermal muscle; developing anatomical structure; embryonic tagma; larval abdominal segment. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG5185-PA translation from_gene[CG5185 Tom FBgn0026320] seq_release:3 mol_weight=18429 cds_boundaries:(3L:14,918,306..14,918,779[+]) aa_length:158 transcript_info:[CG5185-RA seq_release:3] gene_info:[gene symbol:Tom FBgn0026320 gene_boundaries:(3L:14, [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9V3S6) TOM protein (LD05688P) [DrosMelano7227.FASTAC.txt]
  • (AE003532) Tom gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG5185-PA [Drosophila melanogaster]gi|16648272|gb|AAL25401.1| LD05688p [Drosophila melanogaster]gi|6601392|gb|AAF18973.1| BARBU [Drosophila melanogaster]gi|24664355|ref|NP_524073.2| CG5185-PA [Drosophila melanogaster]gi|6540584|gb|AAF16404.1| Twin of [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3L:14962527..14963003; ID=FBpp0075373; name=Tom-PA; parent=FBgn0026320,FBtr0075620; dbxref=FlyBase:FBpp0075373,FlyBase_Annotation_IDs:CG5185-PA,GB_protein:AAF49694.1,REFSEQ:NP_524073,GB_protein:AAF49694; MD5=5b782c61976ee2ac493514e221588 [fly-100309-contam.fasta]
  • Twin of m4 [Drosophila melanogaster] [nr-271106-contam.fasta]
  • BARBU [Drosophila melanogaster] [nr-271106-contam.fasta]
  • LD05688p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG5185-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Twin of m4 CG5185-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3L:14962527..14963003; ID=FBpp0075373; name=Tom-PA; parent=FBgn0026320,FBtr0075620; dbxref=FlyBase:FBpp0075373,FlyBase_Annotation_IDs:CG5185-PA,GB_protein:AAF49694.1,REFSEQ:NP_524073,GB_protein:AAF49694; MD5=5b782c61976ee2ac493514e22158848c; length=158; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3L:14962527..14963003; ID=FBpp0075373; name=Tom-PA; parent=FBgn0026320,FBtr0075620; dbxref=FlyBase:FBpp0075373,FlyBase_Annotation_IDs:CG5185-PA,GB_protein:AAF49694.1,REFSEQ:NP_524073,GB_protein:AAF49694; MD5=5b782c61976ee2ac493514e22158848c; length=158; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • BARBU OS=Drosophila melanogaster GN=Tom PE=1 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=3L:14962527..14963003; ID=FBpp0075373; name=Tom-PA; parent=FBgn0026320,FBtr0075620; dbxref=FlyBase:FBpp0075373,FlyBase_Annotation_IDs:CG5185-PA,GB_protein:AAF49694.1,REFSEQ:NP_524073,GB_protein:AAF49694,FlyMine:FBpp0075373,modMine:FBpp0075373; MD5=5b782c61976ee2ac493514e22158848c; length=158; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • BARBU OS=Drosophila melanogaster GN=Tom PE=2 SV=1 [UniProt_D_Melanogaster_07132012_07-13-2012_reversed.fasta]
  • type=protein; loc=3L:14969427..14969903; ID=FBpp0075373; name=Tom-PA; parent=FBgn0026320,FBtr0075620; dbxref=FlyBase:FBpp0075373,FlyBase_Annotation_IDs:CG5185-PA,GB_protein:AAF49694.1,REFSEQ:NP_524073,GB_protein:AAF49694,FlyMine:FBpp0075373,modMine:FBpp0075373; MD5=5b782c61976ee2ac493514e22158848c; length=158; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3L:14969427..14969903; ID=FBpp0075373; name=Tom-PA; parent=FBgn0026320,FBtr0075620; dbxref=FlyBase:FBpp0075373,FlyBase_Annotation_IDs:CG5185-PA,GB_protein:AAF49694.1,REFSEQ:NP_524073,GB_protein:AAF49694,FlyMine:FBpp0075373,modMine:FBpp0075373; MD5=5b782c61976ee2ac493514e22158848c; length=158; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FBpp0075373 type=protein; loc=3L:14969427..14969903; ID=FBpp0075373; name=Tom-PA; parent=FBgn0026320,FBtr0075620; dbxref=FlyBase:FBpp0075373,FlyBase_Annotation_IDs:CG5185-PA,GB_protein:AAF49694.1,REFSEQ:NP_524073,GB_protein:AAF49694,FlyMine:FBpp0075373,modMine:FBpp0075373; MD5=5b782c61976ee2ac493514e22158848c; length=158; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3L:14969427..14969903; ID=FBpp0075373; name=Tom-PA; parent=FBgn0026320,FBtr0075620; dbxref=FlyBase:FBpp0075373,FlyBase_Annotation_IDs:CG5185-PA,GB_protein:AAF49694.1,REFSEQ:NP_524073,GB_protein:AAF49694,UniProt/TrEMBL:Q9V3S6,FlyMine:FBpp0075373,modMine:FBpp0075373; MD5=5b782c61976ee2ac493514e22158848c; length=158; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 158 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDA]
    Biological Process: Notch signaling pathway [IGI][IMP]
    sensory organ precursor cell fate determination [IMP]
    establishment of planar polarity [IMP]
    cell fate specification [IMP]
    sensory organ development [IMP]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFITREYKF ESSKVMEPKS DQHTMAMRSL RKLVKPLLRL VKKKQLLRKT LAEIQNQNAV  60
   61 NASLEDMRKD PAASCDNMAN EELEQRLYTD LRQCPTNVAM IVQQGQQQSI VPVHPEQTFI 120
  121 PVHFARTTSG TFFWTSAEGA RQHHEQQLRQ QFDRWVQA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..158] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle