Protein Overview: mirr-PB, mirr-PA

General Information:
Name(s) found:	mirr-PB / FBpp0075644 [FlyBase] mirr-PA / FBpp0075643 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|7294553\|gb\|AAF49894.1\| mirror, isoform A [Drosophila melanogaster] [NCBI NR] gi\|24663396\|ref\|NP_729818.1\| mirror, isoform B [Drosophila melanogaster] [NCBI NR] gi\|24663392\|ref\|NP_524047.2\| mirror, isoform A [Drosophila melanogaster] [NCBI NR] gi\|23093572\|gb\|AAN11850.1\| mirror, isoform B [Drosophila melanogaster] [NCBI NR] The gene mirror is referred to in FlyBase by the symbol Dmel\mirr (CG10601, FBgn0014343). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:12686848..12703243. It has the cytological map location 69D3-69D4. Based on sequence similarity, it is predicted to have molecular function</span>: transcription factor activity; transcription activator activity; protein binding. There is experimental evidence that it is involved in the biological process</span>: smoothened signaling pathway; embryonic development via the syncytial blastoderm; equator specification; imaginal disc-derived wing morphogenesis; dorsal appendage formation; compound eye morphogenesis; peripheral nervous system development. 35 alleles are reported. The phenotypes of these alleles are annotated with 17 unique terms, many of which group under: adult segment; adult mesothoracic segment; peripheral nervous system; organ system; egg; postalar bristle; chorion; imaginal precursor; acellular anatomical structure; nervous system. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase] >CG10601-PA translation from_gene[CG10601 mirr FBgn0014343] seq_release:3 mol_weight=66956 cds_boundaries:(3L:12,651,859..12,666,500[+]) aa_length:641 transcript_info:[CG10601-RA seq_release:3] gene_info:[gene symbol:mirr FBgn0014343 gene_boundaries:(3 [hmr_yeast5_DM3-1_pombe.fasta] >CG10601-PB translation from_gene[CG10601 mirr FBgn0014343] seq_release:3 mol_weight=66956 cds_boundaries:(3L:12,651,859..12,666,500[+]) aa_length:641 transcript_info:[CG10601-RB seq_release:3] gene_info:[gene symbol:mirr FBgn0014343 gene_boundaries:(3 [hmr_yeast5_DM3-1_pombe.fasta] (Q9VU01) MIRR protein [DrosMelano7227.FASTAC.txt] (AE003540) mirr gene product [Drosophila melanogaster] [yeastflysequest.fasta] CG10601-PB, isoform B [Drosophila melanogaster]gi\|7294553\|gb\|AAF49894.1\| CG10601-PA, isoform A [Drosophila melanogaster]gi\|24663396\|ref\|NP_729818.1\| CG10601-PB [Drosophila melanogaster]gi\|24663392\|ref\|NP_524047.2\| CG10601-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=3L:join(12687412..12687453,12689600..12690103,12698320..12698426,12700475..12700773,12701083..12702056); ID=FBpp0075643; name=mirr-PA; parent=FBgn0014343,FBtr0075911; dbxref=FlyBase:FBpp0075643,FlyBase_Annotation_IDs:CG10601-PA,GB_protei [fly-100309-contam.fasta] type=protein; loc=3L:join(12687412..12687453,12689600..12690103,12698320..12698426,12700475..12700773,12701083..12702056); ID=FBpp0075644; name=mirr-PB; parent=FBgn0014343,FBtr0075912; dbxref=FlyBase:FBpp0075644,FlyBase_Annotation_IDs:CG10601-PB,GB_protei [fly-100309-contam.fasta] CG10601-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta] mirror CG10601-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta] CG10601-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] mirror CG10601-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=3L:join(12687412..12687453,12689600..12690103,12698320..12698426,12700475..12700773,12701083..12702056); ID=FBpp0075643; name=mirr-PA; parent=FBgn0014343,FBtr0075911; dbxref=FlyBase:FBpp0075643,FlyBase_Annotation_IDs:CG10601-PA,GB_protein:AAF49894.1,REFSEQ:NP_524047,GB_protein:AAF49894; MD5=70b9fed1de14ee057f701e261da3da8c; length=641; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=3L:join(12687412..12687453,12689600..12690103,12698320..12698426,12700475..12700773,12701083..12702056); ID=FBpp0075644; name=mirr-PB; parent=FBgn0014343,FBtr0075912; dbxref=FlyBase:FBpp0075644,FlyBase_Annotation_IDs:CG10601-PB,GB_protein:AAN11850.1,REFSEQ:NP_729818,GB_protein:AAN11850; MD5=70b9fed1de14ee057f701e261da3da8c; length=641; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=3L:join(12687412..12687453,12689600..12690103,12698320..12698426,12700475..12700773,12701083..12702056); ID=FBpp0075643; name=mirr-PA; parent=FBgn0014343,FBtr0075911; dbxref=FlyBase:FBpp0075643,FlyBase_Annotation_IDs:CG10601-PA,GB_protein:AAF49894.1,REFSEQ:NP_524047,GB_protein:AAF49894; MD5=70b9fed1de14ee057f701e261da3da8c; length=641; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] type=protein; loc=3L:join(12687412..12687453,12689600..12690103,12698320..12698426,12700475..12700773,12701083..12702056); ID=FBpp0075644; name=mirr-PB; parent=FBgn0014343,FBtr0075912; dbxref=FlyBase:FBpp0075644,FlyBase_Annotation_IDs:CG10601-PB,GB_protein:AAN11850.1,REFSEQ:NP_729818,GB_protein:AAN11850; MD5=70b9fed1de14ee057f701e261da3da8c; length=641; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] Mirror, isoform A OS=Drosophila melanogaster GN=mirr PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=3L:join(12687412..12687453,12689600..12690103,12698320..12698426,12700475..12700773,12701083..12702056); ID=FBpp0075643; name=mirr-PA; parent=FBgn0014343,FBtr0075911; dbxref=FlyBase:FBpp0075643,FlyBase_Annotation_IDs:CG10601-PA,GB_protein:AAF49894.1,REFSEQ:NP_524047,GB_protein:AAF49894,FlyMine:FBpp0075643,modMine:FBpp0075643; MD5=70b9fed1de14ee057f701e261da3da8c; length=641; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=3L:join(12687412..12687453,12689600..12690103,12698320..12698426,12700475..12700773,12701083..12702056); ID=FBpp0075644; name=mirr-PB; parent=FBgn0014343,FBtr0075912; dbxref=FlyBase:FBpp0075644,FlyBase_Annotation_IDs:CG10601-PB,GB_protein:AAN11850.1,REFSEQ:NP_729818,GB_protein:AAN11850; MD5=70b9fed1de14ee057f701e261da3da8c; length=641; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=3L:join(12694312..12694353,12696500..12697003,12705220..12705326,12707375..12707673,12707983..12708956); ID=FBpp0075643; name=mirr-PA; parent=FBgn0014343,FBtr0075911; dbxref=FlyBase:FBpp0075643,FlyBase_Annotation_IDs:CG10601-PA,GB_protein:AAF49894.1,REFSEQ:NP_524047,GB_protein:AAF49894,FlyMine:FBpp0075643,modMine:FBpp0075643; MD5=70b9fed1de14ee057f701e261da3da8c; length=641; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=3L:join(12694312..12694353,12696500..12697003,12705220..12705326,12707375..12707673,12707983..12708956); ID=FBpp0075644; name=mirr-PB; parent=FBgn0014343,FBtr0075912; dbxref=FlyBase:FBpp0075644,FlyBase_Annotation_IDs:CG10601-PB,GB_protein:AAN11850.1,REFSEQ:NP_729818,GB_protein:AAN11850; MD5=70b9fed1de14ee057f701e261da3da8c; length=641; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=3L:join(12694312..12694353,12696500..12697003,12705220..12705326,12707375..12707673,12707983..12708956); ID=FBpp0075643; name=mirr-PA; parent=FBgn0014343,FBtr0075911; dbxref=FlyBase:FBpp0075643,FlyBase_Annotation_IDs:CG10601-PA,GB_protein:AAF49894.1,REFSEQ:NP_524047,GB_protein:AAF49894,FlyMine:FBpp0075643,modMine:FBpp0075643; MD5=70b9fed1de14ee057f701e261da3da8c; length=641; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] type=protein; loc=3L:join(12694312..12694353,12696500..12697003,12705220..12705326,12707375..12707673,12707983..12708956); ID=FBpp0075644; name=mirr-PB; parent=FBgn0014343,FBtr0075912; dbxref=FlyBase:FBpp0075644,FlyBase_Annotation_IDs:CG10601-PB,GB_protein:AAN11850.1,REFSEQ:NP_729818,GB_protein:AAN11850; MD5=70b9fed1de14ee057f701e261da3da8c; length=641; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] Isoform of M9PI45, Mirror, isoform A OS=Drosophila melanogaster GN=mirr PE=4 SV=1 [DROME.fasta.20160308] FBpp0075643 type=protein; loc=3L:join(12694312..12694353,12696500..12697003,12705220..12705326,12707375..12707673,12707983..12708956); ID=FBpp0075643; name=mirr-PA; parent=FBgn0014343,FBtr0075911; dbxref=FlyBase:FBpp0075643,FlyBase_Annotation_IDs:CG10601-PA,GB_protein:AAF49894.1,REFSEQ:NP_524047,GB_protein:AAF49894,FlyMine:FBpp0075643,modMine:FBpp0075643; MD5=70b9fed1de14ee057f701e261da3da8c; length=641; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] FBpp0075644 type=protein; loc=3L:join(12694312..12694353,12696500..12697003,12705220..12705326,12707375..12707673,12707983..12708956); ID=FBpp0075644; name=mirr-PB; parent=FBgn0014343,FBtr0075912; dbxref=FlyBase:FBpp0075644,FlyBase_Annotation_IDs:CG10601-PB,GB_protein:AAN11850.1,REFSEQ:NP_729818,GB_protein:AAN11850; MD5=70b9fed1de14ee057f701e261da3da8c; length=641; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=3L:join(12694312..12694353,12696500..12697003,12705220..12705326,12707375..12707673,12707983..12708956); ID=FBpp0075643; name=mirr-PA; parent=FBgn0014343,FBtr0075911; dbxref=FlyBase:FBpp0075643,FlyBase_Annotation_IDs:CG10601-PA,GB_protein:AAF49894.1,REFSEQ:NP_524047,GB_protein:AAF49894,UniProt/TrEMBL:Q9VU01,FlyMine:FBpp0075643,modMine:FBpp0075643; MD5=70b9fed1de14ee057f701e261da3da8c; length=641; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta] type=protein; loc=3L:join(12694312..12694353,12696500..12697003,12705220..12705326,12707375..12707673,12707983..12708956); ID=FBpp0075644; name=mirr-PB; parent=FBgn0014343,FBtr0075912; dbxref=FlyBase:FBpp0075644,FlyBase_Annotation_IDs:CG10601-PB,GB_protein:AAN11850.1,REFSEQ:NP_729818,GB_protein:AAN11850,UniProt/TrEMBL:Q9VU01; MD5=70b9fed1de14ee057f701e261da3da8c; length=641; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	641 amino acids
Gene Ontology:
Cellular Component:	nucleus [ISS]
Biological Process:	embryonic development via the syncytial blastoderm [IEP][IMP] compound eye morphogenesis [IMP] imaginal disc-derived wing morphogenesis [IMP] positive regulation of transcription [ISS] peripheral nervous system development [IMP] regulation of transcription, DNA-dependent [IEA][ISS] smoothened signaling pathway [IGI] dorsal appendage formation [IMP] equator specification [IMP][TAS] regulation of transcription [IEA]
Molecular Function:	transcription factor activity [ISS][NAS] protein binding [ISS] sequence-specific DNA binding [IEA] transcription activator activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTVHSNETGI CLVMNAVSTH LATSSPNTPP TNAPQSPPST LPTLACPAAQ PLSAPGIAGP  60
   61 GHSGMVTSTV PPGARSTSPC GPSAGLPALS LVGAPPPGPH SSAPGGAPAP GAGNPPNRCC 120
  121 DTGRTIYTDP VSGQTICSCQ YDMLNYQRLA AAGGVPLGVY PEGMSAYLSG IAADQPPFYA 180
  181 NPAGIDLKEN LVAGASPWPY PSMYHPYDAA FAGYPFNSYG MDLNGARRKN ATRETTSTLK 240
  241 AWLNEHKKNP YPTKGEKIML AIITKMTLTQ VSTWFANARR RLKKENKMTW EPRNRVDDDD 300
  301 ANIDDDDDKN TEDNDLLDAK DSGVGSTDDK DRSGRLGDMM TDRPGESNNS EWSESRPGSP 360
  361 NGSPDLYDRP GSMPPGAHPL FHPAALHHHF RPPAGSPPDI AAYHHHQQQL LQQHQQAQQN 420
  421 SLQTAVGGTA KPRIWSLADM ASKDSKDSSS GAKDNHPELP PAHPGFYGHP GQQPSPGKIL 480
  481 SPLAARIPNY SPYVRPDLYR GFYGPAAAHL GAPTQEFLEH QRTFGASLAA HNGPLGMNPL 540
  541 LWKAAVSGAA NGHHFAPLSL TTSGGSSGGQ QVAPPPVASP SASSSSSSMG CDVVHIPTSS 600
  601 GQSAAQHMMG PISSNSTASS SSSHSGKISP GVNVTSLSAK P

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.79

Protein Overview: mirr-PB, mirr-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: