Protein Overview: JIL-1-PA, JIL-1-...

General Information:
Name(s) found:	FBpp0304953 [FlyBase] JIL-1-PA / FBpp0075966 [FlyBase] JIL-1-PB / FBpp0075965 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|73920079\|sp\|Q9V3I5.1\|JIL1_DROME RecName: Full=Chromosomal serine/threonine-protein kinase JIL-1 [NCBI NR] gi\|7294770\|gb\|AAF50105.1\| JIL-1, isoform B [Drosophila melanogaster] [NCBI NR] gi\|5726308\|gb\|AAD48407.1\|AF142061_1 protein kinase JIL-1 [Drosophila melanogaster] [NCBI NR] gi\|24662468\|ref\|NP_729661.1\| JIL-1, isoform A [Drosophila melanogaster] [NCBI NR] gi\|23093672\|gb\|AAN11898.1\| JIL-1, isoform A [Drosophila melanogaster] [NCBI NR] gi\|21356509\|ref\|NP_648432.1\| JIL-1, isoform B [Drosophila melanogaster] [NCBI NR] gi\|202027870\|gb\|ACH95258.1\| AT31317p [Drosophila melanogaster] [NCBI NR] Chromosomal serine/threonine-protein kinase JIL-1 OS=Drosophila melanogaster GN=JIL-1 PE=1 SV=1 [Swiss-Prot] type=protein; loc=3L:complement(11073723..11075055,11075116..11075564,11075626..11076437,11076501..11076585,11078529..11078662,11078740..11078808,11083998..11084739); ID=FBpp0304953; name=JIL-1-PC; parent=FBgn0020412,FBtr0332707; dbxref=REFSEQ:NP_001261697,GB_protein:AGB94391,FlyBase:FBpp0304953,FlyBase_Annotation_IDs:CG6297-PC; MD5=d1c893d60f2abf8f1f2053b21cef3dcb; length=1207; release=r5.56; species=Dmel; [FlyBase] The gene JIL-1 is referred to in FlyBase by the symbol Dmel\JIL-1 (CG6297, FBgn0020412). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:11071849..11086239. It has the cytological map location 68A5-68A6. There is experimental evidence that it has the molecular function</span>: histone kinase activity (H3-S10 specific); protein kinase activity. There is experimental evidence that it is involved in the biological process</span>: female meiosis chromosome segregation; negative regulation of chromatin silencing; chromatin organization; chromosome organization; oogenesis. 45 alleles are reported. The phenotypes of these alleles are annotated with 13 unique terms, many of which group under: anatomical structure; organ system; intracellular organelle part; intracellular non-membrane-bounded organelle; intracellular organelle; female germline cyst; chromatin; organism; chromosome; spindle; nucleus; egg; multi-cell-component structure. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase] >CG6297-PB translation from_gene[CG6297 JIL-1 FBgn0020412] seq_release:3 mol_weight=137046 cds_boundaries:(3L:11,038,158..11,049,171[-]) aa_length:1207 transcript_info:[CG6297-RB seq_release:3] gene_info:[gene symbol:JIL-1 FBgn0020412 gene_boundaries:( [hmr_yeast5_DM3-1_pombe.fasta] >CG6297-PA translation from_gene[CG6297 JIL-1 FBgn0020412] seq_release:3 mol_weight=137046 cds_boundaries:(3L:11,038,158..11,049,171[-]) aa_length:1207 transcript_info:[CG6297-RA seq_release:3] gene_info:[gene symbol:JIL-1 FBgn0020412 gene_boundaries:( [hmr_yeast5_DM3-1_pombe.fasta] (Q9V3I5) JIL-1 protein [DrosMelano7227.FASTAC.txt] (AE003546) JIL-1 gene product [Drosophila melanogaster] [yeastflysequest.fasta] CG6297-PB, isoform B [Drosophila melanogaster]gi\|23093672\|gb\|AAN11898.1\| CG6297-PA, isoform A [Drosophila melanogaster]gi\|24662468\|ref\|NP_729661.1\| CG6297-PA [Drosophila melanogaster]gi\|5726308\|gb\|AAD48407.1\| protein kinase JIL-1 [Drosophila melanogast [nrdb_11152004_Chlamydomonas] type=protein; loc=3L:complement(11073723..11075055,11075116..11075564,11075626..11076437,11076501..11076585,11078529..11078662,11078740..11078808,11083998..11084739); ID=FBpp0075965; name=JIL-1-PB; parent=FBgn0020412,FBtr0076236; dbxref=FlyBase:FBpp007596 [fly-100309-contam.fasta] type=protein; loc=3L:complement(11073723..11075055,11075116..11075564,11075626..11076437,11076501..11076585,11078529..11078662,11078740..11078808,11083998..11084739); ID=FBpp0075966; name=JIL-1-PA; parent=FBgn0020412,FBtr0076237; dbxref=FlyBase:FBpp007596 [fly-100309-contam.fasta] CG6297-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta] JIL-1 CG6297-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] Chromosomal serine/threonine-protein kinase JIL-1 [nr-271106-contam.fasta] JIL-1 CG6297-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta] CG6297-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta] protein kinase JIL-1 [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=3L:complement(11073723..11075055,11075116..11075564,11075626..11076437,11076501..11076585,11078529..11078662,11078740..11078808,11083998..11084739); ID=FBpp0075965; name=JIL-1-PB; parent=FBgn0020412,FBtr0076236; dbxref=FlyBase:FBpp0075965,FlyBase_Annotation_IDs:CG6297-PB,GB_protein:AAF50105.1,REFSEQ:NP_648432,GB_protein:AAF50105; MD5=d1c893d60f2abf8f1f2053b21cef3dcb; length=1207; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=3L:complement(11073723..11075055,11075116..11075564,11075626..11076437,11076501..11076585,11078529..11078662,11078740..11078808,11083998..11084739); ID=FBpp0075966; name=JIL-1-PA; parent=FBgn0020412,FBtr0076237; dbxref=FlyBase:FBpp0075966,FlyBase_Annotation_IDs:CG6297-PA,GB_protein:AAN11898.1,REFSEQ:NP_729661,GB_protein:AAN11898; MD5=d1c893d60f2abf8f1f2053b21cef3dcb; length=1207; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=3L:complement(11073723..11075055,11075116..11075564,11075626..11076437,11076501..11076585,11078529..11078662,11078740..11078808,11083998..11084739); ID=FBpp0075965; name=JIL-1-PB; parent=FBgn0020412,FBtr0076236; dbxref=FlyBase:FBpp0075965,FlyBase_Annotation_IDs:CG6297-PB,GB_protein:AAF50105.1,REFSEQ:NP_648432,GB_protein:AAF50105; MD5=d1c893d60f2abf8f1f2053b21cef3dcb; length=1207; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] type=protein; loc=3L:complement(11073723..11075055,11075116..11075564,11075626..11076437,11076501..11076585,11078529..11078662,11078740..11078808,11083998..11084739); ID=FBpp0075966; name=JIL-1-PA; parent=FBgn0020412,FBtr0076237; dbxref=FlyBase:FBpp0075966,FlyBase_Annotation_IDs:CG6297-PA,GB_protein:AAN11898.1,REFSEQ:NP_729661,GB_protein:AAN11898; MD5=d1c893d60f2abf8f1f2053b21cef3dcb; length=1207; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] type=protein; loc=3L:complement(11073723..11075055,11075116..11075564,11075626..11076437,11076501..11076585,11078529..11078662,11078740..11078808,11083998..11084739); ID=FBpp0075965; name=JIL-1-PB; parent=FBgn0020412,FBtr0076236; dbxref=FlyBase:FBpp0075965,FlyBase_Annotation_IDs:CG6297-PB,GB_protein:AAF50105.1,REFSEQ:NP_648432,GB_protein:AAF50105,FlyMine:FBpp0075965,modMine:FBpp0075965; MD5=d1c893d60f2abf8f1f2053b21cef3dcb; length=1207; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=3L:complement(11073723..11075055,11075116..11075564,11075626..11076437,11076501..11076585,11078529..11078662,11078740..11078808,11083998..11084739); ID=FBpp0075966; name=JIL-1-PA; parent=FBgn0020412,FBtr0076237; dbxref=FlyBase:FBpp0075966,FlyBase_Annotation_IDs:CG6297-PA,GB_protein:AAN11898.1,REFSEQ:NP_729661,GB_protein:AAN11898; MD5=d1c893d60f2abf8f1f2053b21cef3dcb; length=1207; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=3L:complement(11073723..11075055,11075116..11075564,11075626..11076437,11076501..11076585,11078529..11078662,11078740..11078808,11083998..11084739); ID=FBpp0304953; name=JIL-1-PC; parent=FBgn0020412,FBtr0332707; dbxref=FlyBase:FBpp0304953,FlyBase_Annotation_IDs:CG6297-PC; MD5=d1c893d60f2abf8f1f2053b21cef3dcb; length=1207; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] JIL-1, isoform B [Drosophila melanogaster] [RJAZ10-comet.fasta] type=protein; loc=3L:complement(join(11090898..11091639,11085640..11085708,11085429..11085562,11083401..11083485,11082526..11083337,11082016..11082464,11080623..11081955)); ID=FBpp0075965; name=JIL-1-PB; parent=FBgn0020412,FBtr0076236; dbxref=FlyBase:FBpp0075965,FlyBase_Annotation_IDs:CG6297-PB,GB_protein:AAF50105.1,REFSEQ:NP_648432,GB_protein:AAF50105,FlyMine:FBpp0075965,modMine:FBpp0075965; MD5=d1c893d60f2abf8f1f2053b21cef3dcb; length=1207; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=3L:complement(join(11090898..11091639,11085640..11085708,11085429..11085562,11083401..11083485,11082526..11083337,11082016..11082464,11080623..11081955)); ID=FBpp0075966; name=JIL-1-PA; parent=FBgn0020412,FBtr0076237; dbxref=FlyBase:FBpp0075966,FlyBase_Annotation_IDs:CG6297-PA,GB_protein:AAN11898.1,REFSEQ:NP_729661,GB_protein:AAN11898; MD5=d1c893d60f2abf8f1f2053b21cef3dcb; length=1207; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=3L:complement(join(11090898..11091639,11085640..11085708,11085429..11085562,11083401..11083485,11082526..11083337,11082016..11082464,11080623..11081955)); ID=FBpp0304953; name=JIL-1-PC; parent=FBgn0020412,FBtr0332707; dbxref=REFSEQ:NP_001261697,GB_protein:AGB94391,FlyBase:FBpp0304953,FlyBase_Annotation_IDs:CG6297-PC; MD5=d1c893d60f2abf8f1f2053b21cef3dcb; length=1207; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=3L:complement(join(11090898..11091639,11085640..11085708,11085429..11085562,11083401..11083485,11082526..11083337,11082016..11082464,11080623..11081955)); ID=FBpp0075965; name=JIL-1-PB; parent=FBgn0020412,FBtr0076236; dbxref=FlyBase:FBpp0075965,FlyBase_Annotation_IDs:CG6297-PB,GB_protein:AAF50105.1,REFSEQ:NP_648432,GB_protein:AAF50105,FlyMine:FBpp0075965,modMine:FBpp0075965; MD5=d1c893d60f2abf8f1f2053b21cef3dcb; length=1207; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] type=protein; loc=3L:complement(join(11090898..11091639,11085640..11085708,11085429..11085562,11083401..11083485,11082526..11083337,11082016..11082464,11080623..11081955)); ID=FBpp0075966; name=JIL-1-PA; parent=FBgn0020412,FBtr0076237; dbxref=FlyBase:FBpp0075966,FlyBase_Annotation_IDs:CG6297-PA,GB_protein:AAN11898.1,REFSEQ:NP_729661,GB_protein:AAN11898; MD5=d1c893d60f2abf8f1f2053b21cef3dcb; length=1207; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] type=protein; loc=3L:complement(join(11090898..11091639,11085640..11085708,11085429..11085562,11083401..11083485,11082526..11083337,11082016..11082464,11080623..11081955)); ID=FBpp0304953; name=JIL-1-PC; parent=FBgn0020412,FBtr0332707; dbxref=REFSEQ:NP_001261697,GB_protein:AGB94391,FlyBase:FBpp0304953,FlyBase_Annotation_IDs:CG6297-PC; MD5=d1c893d60f2abf8f1f2053b21cef3dcb; length=1207; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] Isoform of Q9V3I5, JIL-1 kinase, isoform C OS=Drosophila melanogaster GN=JIL-1 PE=1 SV=1 [DROME.fasta.20160308] FBpp0075965 type=protein; loc=3L:complement(join(11090898..11091639,11085640..11085708,11085429..11085562,11083401..11083485,11082526..11083337,11082016..11082464,11080623..11081955)); ID=FBpp0075965; name=JIL-1-PB; parent=FBgn0020412,FBtr0076236; dbxref=FlyBase:FBpp0075965,FlyBase_Annotation_IDs:CG6297-PB,GB_protein:AAF50105.1,REFSEQ:NP_648432,GB_protein:AAF50105,FlyMine:FBpp0075965,modMine:FBpp0075965; MD5=d1c893d60f2abf8f1f2053b21cef3dcb; length=1207; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] FBpp0075966 type=protein; loc=3L:complement(join(11090898..11091639,11085640..11085708,11085429..11085562,11083401..11083485,11082526..11083337,11082016..11082464,11080623..11081955)); ID=FBpp0075966; name=JIL-1-PA; parent=FBgn0020412,FBtr0076237; dbxref=FlyBase:FBpp0075966,FlyBase_Annotation_IDs:CG6297-PA,GB_protein:AAN11898.1,REFSEQ:NP_729661,GB_protein:AAN11898; MD5=d1c893d60f2abf8f1f2053b21cef3dcb; length=1207; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] FBpp0304953 type=protein; loc=3L:complement(join(11090898..11091639,11085640..11085708,11085429..11085562,11083401..11083485,11082526..11083337,11082016..11082464,11080623..11081955)); ID=FBpp0304953; name=JIL-1-PC; parent=FBgn0020412,FBtr0332707; dbxref=REFSEQ:NP_001261697,GB_protein:AGB94391,FlyBase:FBpp0304953,FlyBase_Annotation_IDs:CG6297-PC; MD5=d1c893d60f2abf8f1f2053b21cef3dcb; length=1207; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=3L:complement(join(11090898..11091639,11085640..11085708,11085429..11085562,11083401..11083485,11082526..11083337,11082016..11082464,11080623..11081955)); ID=FBpp0075965; name=JIL-1-PB; parent=FBgn0020412,FBtr0076236; dbxref=FlyBase:FBpp0075965,FlyBase_Annotation_IDs:CG6297-PB,GB_protein:AAF50105.1,REFSEQ:NP_648432,GB_protein:AAF50105,UniProt/Swiss-Prot:Q9V3I5,FlyMine:FBpp0075965,modMine:FBpp0075965; MD5=d1c893d60f2abf8f1f2053b21cef3dcb; length=1207; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta] type=protein; loc=3L:complement(join(11090898..11091639,11085640..11085708,11085429..11085562,11083401..11083485,11082526..11083337,11082016..11082464,11080623..11081955)); ID=FBpp0075966; name=JIL-1-PA; parent=FBgn0020412,FBtr0076237; dbxref=FlyBase:FBpp0075966,FlyBase_Annotation_IDs:CG6297-PA,GB_protein:AAN11898.1,REFSEQ:NP_729661,GB_protein:AAN11898,UniProt/Swiss-Prot:Q9V3I5; MD5=d1c893d60f2abf8f1f2053b21cef3dcb; length=1207; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta] type=protein; loc=3L:complement(join(11090898..11091639,11085640..11085708,11085429..11085562,11083401..11083485,11082526..11083337,11082016..11082464,11080623..11081955)); ID=FBpp0304953; name=JIL-1-PC; parent=FBgn0020412,FBtr0332707; dbxref=REFSEQ:NP_001261697,GB_protein:AGB94391,FlyBase:FBpp0304953,FlyBase_Annotation_IDs:CG6297-PC,UniProt/Swiss-Prot:Q9V3I5; MD5=d1c893d60f2abf8f1f2053b21cef3dcb; length=1207; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	1207 amino acids
Gene Ontology:
Cellular Component:	nuclear chromatin [IDA] X chromosome located dosage compensation complex, transcription activating [IPI]
Biological Process:	oogenesis [IMP] chromosome organization [IMP] negative regulation of chromatin silencing [IMP] histone phosphorylation [TAS] female meiosis chromosome segregation [IMP] protein amino acid phosphorylation [IEA][ISS][NAS] chromatin organization [IMP][TAS]
Molecular Function:	ATP binding [IEA] histone kinase activity (H3-S10 specific) [IMP][TAS] protein kinase activity [IDA] protein serine/threonine kinase activity [ISS][NAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSRLQKQNYE ILSGTSTSRL KNHQHPRESE SLAYEEPDQM VRNHLNGQLV ANGNGKTRKN  60
   61 SNSETMTNGK KSKLNTEGSG SGSGKTLNYN NNNNNNNSIS ATNGQYTNSS SKTTSASARD 120
  121 YTYRETISPP TPPSPPTTNV ADIVCISDAE SEDGRDPERE YYDQDMEEDE PNGIEIDESS 180
  181 SSLSKAKSNN AAAAAAAAAA AAAAAASKAS SSTTPSYAMP TSNSTPLDLD NEAHQRDLEA 240
  241 VTDLKYYVKL YSDEAVSLND FKIIRVLGTG AYGRVFLVRK LTRHDAGKLY AMKVLNKITV 300
  301 VQKRKTAEHT KTERVVLEAI QRNPFLVSLH YAFQSSSKLY LVLDFANGGE LFTHLYHSEN 360
  361 FEESRVRVYI AEVVLALEQL HQLGIIYRDI KLENILLDGE GHIVLSDFGL SKILTAENEY 420
  421 RAHSFCGTLE YMAPEIIRTG PPGHDSAVDW WSVGVLTFEL LTGASPFATS DGQVQQSEIS 480
  481 RRIQKEQPMI PSSFSANARD FVLKMLEKNP KRRLGGNHRD ASEIKEHPFF NGINWQELRT 540
  541 KRRKAPYKPT LTAEDDVQNF SNEFTDQVPE DPECDAPPSR IRLFRGYTYV APEHLEQMRR 600
  601 DNHCEIQYFN TGLQNIPCRP DDLELGTRTS NGAYGTCHFV VDSSTDLVFL AKIIPLSKFR 660
  661 PSEVDALISC ALDTTNHKNI VSYHGTFREK CETWIVMEYL SGPELTASIR MDEDSCREIF 720
  721 LQLVMAVRHI HSKHFIHGDL KPENIMFENR EDRTVKLIDF GSACYNNRFK SWKDKPRYTL 780
  781 DYAPPEMLAD ANLVTYSPAV DIYGLGATLY TMLVGHRPYR QNEDDVDHSA AAHHELRKRM 840
  841 RRGTFNQRSM RWESASPAFR HLVSWCLQRD PADRPTLSDI LDSEWLQYGS NDPDVDIILP 900
  901 QQMVVDLSED TMEQPTGGMF DDQQQLEFMH DKSAEDEGIT LVSEPMDTTV ATHESRRNAA 960
  961 AFSSVVAPTT DDEIVHERFD PAFEVQADFY GFDENAPPLP LPEEYYSELP LPEEDRQYIP1020
 1021 PPPALIPVEP ETTFRRPRTR QQRRTESQLV QPVSVATYED SKASLRVLMQ QLPPPGDNVV1080
 1081 ARIPKRTHRV VRTLPPTFGT TKREENFYGF SKTAISWRKT RASWRHFCLL INGVQQVLKV1140
 1141 RFKKARRVYC LPHIKEEKLD HAYEKPLTFP RPKAQLKRTK REPKVPRPPT RVQPERARAM1200
 1201 RQLYQFQ

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.85

Protein Overview: JIL-1-PA, JIL-1-...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: