Protein Overview: hay-PB, hay-PA

General Information:
Name(s) found:	hay-PB / FBpp0113091 [FlyBase] hay-PA / FBpp0075982 [FlyBase]
Description(s) found: Found 36 descriptions. SHOW ALL	The gene haywire is referred to in FlyBase by the symbol Dmel\hay (CG8019, FBgn0001179). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:10624227..10627069. It has the cytological map location 67E5. Based on sequence similarity, it is predicted to have molecular function</span>: general RNA polymerase II transcription factor activity; helicase activity. There is experimental evidence that it is involved in the biological process</span>: adult locomotory behavior; regulation of alternative nuclear mRNA splicing, via spliceosome; response to UV. 29 alleles are reported. The phenotypes of these alleles are annotated with: wing margin; macrochaeta; chaeta; wing; imaginal disc; microchaeta; larval central nervous system. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase] The gene haywire is referred to in FlyBase by the symbol Dmel\hay (CG8019, FBgn0001179). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:10624227..10627069. It has the cytological map location 67E5. Based on sequence similarity, it is predicted to have molecular function</span>: general RNA polymerase II transcription factor activity; helicase activity. There is experimental evidence that it is involved in the biological process</span>: adult locomotory behavior; regulation of alternative nuclear mRNA splicing, via spliceosome; response to UV. 29 alleles are reported. The phenotypes of these alleles are annotated with: wing margin; macrochaeta; chaeta; wing; imaginal disc; microchaeta; larval central nervous system. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	798 amino acids
Gene Ontology:
Cellular Component:	nucleus [IC][NAS] holo TFIIH complex [ISS]
Biological Process:	regulation of alternative nuclear mRNA splicing, via spliceosome [IMP] nucleotide-excision repair [ISS] adult locomotory behavior [IMP] response to UV [IMP] transcription initiation from RNA polymerase II promoter [ISS]
Molecular Function:	DNA binding [IEA] ATP binding [IEA] general RNA polymerase II transcription factor activity [ISS] helicase activity [ISS] ATP-dependent DNA helicase activity [IEA][NAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGPPKKSRKD RSGGDKFGKK RRAEDEAFTQ LVDDNDSLDA TESEGIPGAA SKNAETNDEQ  60
   61 INTDEYGAKD YRSQMQLRPD HGNRPLWVAP NGHVFLESFS PVYKHAHDFL IAISEPVCRP 120
  121 EHIHEYKLTA YSLYAAVSVG LQTHDIVEYL KRLSKTSIPE GILEFIRLCT LSYGKVKLVL 180
  181 KHNKYFIESP HPEVLQKLLK DPVIQKCRLI RSEGEDFIQG TLDGKAITQF GTKLPPGATD 240
  241 KPTPDPAAAA GADGTTAVPE DITDFYEKID KEEEDEDEAN LKTVSFEVAQ EKIEVIQKRC 300
  301 IEIEHPLLAE YDFRNDTNNP DINIDLKPAA VLRPYQEKSL RKMFGNGRAR SGVIVLPCGA 360
  361 GKSLVGVTAC CTVRKRALVL CNSGVSVEQW KQQFKMWSTA DDSMICRFTS EAKDKPMGCG 420
  421 ILVTTYSMIT HTQKRSWEAE QTMRWLQEQE WGIMVLDEVH TIPAKMFRRV LTIVQSHCKL 480
  481 GLTATLLRED DKIADLNFLI GPKLYEANWL ELQKKGYIAR VQCAEVWCPM SPEFYREYLT 540
  541 TKTSKKMLLY VMNPSKFRSC QFLIKYHEQR GDKTIVFSDN VFALKHYAIK MNKPFIYGPT 600
  601 SQNERIQILQ NFKFNSKVNT IFVSKVADTS FDLPEANVLI QISSHGGSRR QEAQRLGRIL 660
  661 RAKKGAIAEE YNAFFYTLVS QDTMEMSYSR KRQRFLVNQG YSYKVITHLK GMDTDSDLMY 720
  721 GTQEEQGQLL QLVLSASDLD CEDEKLPGEP GYRPSGSGGA VRRVGGLSSM SGGDDAIYYE 780
  781 HRKKNIGSVH PLFKKFRG

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: hay-PB, hay-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: