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Protein Overview: I-2-PA

General Information:
Name(s) found: I-2-PA / FBpp0076099 [FlyBase]
Description(s) found:
Found 28 descriptions.
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  • The gene Inhibitor-2 is referred to in FlyBase by the symbol Dmel\I-2 (CG10574, FBgn0028429). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:9827460..9829896. It has the cytological map location 67C10. There is experimental evidence that it has the molecular function</span>: phosphoprotein phosphatase inhibitor activity. There is experimental evidence that it is involved in the biological process</span>: negative regulation of protein amino acid dephosphorylation. 5 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 205 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: negative regulation of protein amino acid dephosphorylation [IDA][IMP]
    regulation of phosphoprotein phosphatase activity [IEA]
    regulation of signal transduction [IEA]
    Molecular Function: phosphoprotein phosphatase inhibitor activity [IDA][IMP][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQNNPSPQLP CKGILKTSRS FDKSGASFRK SAKFDELNVM QTFHPADKDY GHMKIDEPKT  60
   61 PYNYTEGFDE NRDELDTELL VEKLRIAANT QPSTESIEDD GSSGDDQPLS EEERQRRREF 120
  121 ERRRKAHYRE FEAVKLARKL IQEEDDDDDD EDKGADSRPS GSSQGASSSG RFASSSTKRS 180
  181 SSQADSTTSP STSAGQNMDL EPSNN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..205] PSI-BLAST 65.522879 No description for 2o8aI was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle