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Protein Overview: Hsp22-PB, Hsp22-PA

General Information:
Name(s) found: Hsp22-PB / FBpp0100011 [FlyBase]
Hsp22-PA / FBpp0100010 [FlyBase]
Description(s) found:
Found 36 descriptions.
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  • The gene Heat shock protein 22 is referred to in FlyBase by the symbol Dmel\Hsp22 (CG4460, FBgn0001223). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:9366031..9368070. It has the cytological map location 67B2. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: determination of adult lifespan; response to oxidative stress; response to heat. 11 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • The gene Heat shock protein 22 is referred to in FlyBase by the symbol Dmel\Hsp22 (CG4460, FBgn0001223). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:9366031..9368070. It has the cytological map location 67B2. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: determination of adult lifespan; response to oxidative stress; response to heat. 11 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 174 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: response to oxidative stress [IMP]
    response to heat [IMP][ISS][NAS]
    determination of adult lifespan [IMP]
    protein refolding [NAS]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRSLPMFWRM AEEMARMPRL SSPFHAFFHE PPVWSVALPR NWQQIARWQE QEFAPPATVN  60
   61 KDGYKLTLDV KDYSELKVKV LDESVVLVEG KSEQQEAEQG GYSSRHFLRR FVLPEGYEAD 120
  121 KVTSTLSSDG VLTISVPNPP GVQETLKERE VTIEQTGEPA KKSAEEPNDK AASQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..174] PSI-BLAST 11.30103 CRYSTAL STRUCTURE AND ASSEMBLY OF TSP36, A METAZOAN SMALL HEAT SHOCK PROTEIN


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.68

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle