Protein Overview: exex-PA

General Information:
Name(s) found:	exex-PA / FBpp0076468 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|7295179\|gb\|AAF50503.1\| extra-extra [Drosophila melanogaster] [NCBI NR] gi\|21356351\|ref\|NP_648164.1\| extra-extra [Drosophila melanogaster] [NCBI NR] gi\|19527577\|gb\|AAL89903.1\| RE39081p [Drosophila melanogaster] [NCBI NR] The gene extra-extra is referred to in FlyBase by the symbol Dmel\exex (CG8254, FBgn0041156). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:7941291..7944667. It has the cytological map location 66A21. Based on sequence similarity, it is predicted to have molecular function</span>: transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: central nervous system development; axon target recognition. 11 alleles are reported. The phenotypes of these alleles are annotated with: RP5 neuron; EW1 neuron; RP3 neuron; intersegmental nerve; EW3 neuron; RP1 neuron; embryonic central nervous system; RP4 neuron; EW2 neuron. It has one annotated transcript and one annotated polypeptide. [FlyBase] >CG8254-PA translation from_gene[CG8254 exex FBgn0041156] seq_release:3 mol_weight=56770 cds_boundaries:(3L:7,907,896..7,910,470[+]) aa_length:525 transcript_info:[CG8254-RA seq_release:3] gene_info:[gene symbol:exex FBgn0041156 gene_boundaries:(3L:7,9 [hmr_yeast5_DM3-1_pombe.fasta] (Q9VSC2) CG8254 protein (RE39081p) [DrosMelano7227.FASTAC.txt] (AE003557) CG8254 gene product [Drosophila melanogaster] [yeastflysequest.fasta] CG8254-PA [Drosophila melanogaster]gi\|19527577\|gb\|AAL89903.1\| RE39081p [Drosophila melanogaster]gi\|21356351\|ref\|NP_648164.1\| CG8254-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=3L:join(7941466..7942385,7943251..7943521,7943657..7944043); ID=FBpp0076468; name=exex-PA; parent=FBgn0041156,FBtr0076751; dbxref=FlyBase:FBpp0076468,FlyBase_Annotation_IDs:CG8254-PA,GB_protein:AAF50503.1,REFSEQ:NP_648164,GB_protein:AAF5 [fly-100309-contam.fasta] CG8254-PA [Drosophila melanogaster] [nr-271106-contam.fasta] RE39081p [Drosophila melanogaster] [nr-271106-contam.fasta] extra-extra CG8254-PA [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=3L:join(7941466..7942385,7943251..7943521,7943657..7944043); ID=FBpp0076468; name=exex-PA; parent=FBgn0041156,FBtr0076751; dbxref=FlyBase:FBpp0076468,FlyBase_Annotation_IDs:CG8254-PA,GB_protein:AAF50503.1,REFSEQ:NP_648164,GB_protein:AAF50503; MD5=e85c436b5893a7fa2213f99e412e69f2; length=525; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=3L:join(7941466..7942385,7943251..7943521,7943657..7944043); ID=FBpp0076468; name=exex-PA; parent=FBgn0041156,FBtr0076751; dbxref=FlyBase:FBpp0076468,FlyBase_Annotation_IDs:CG8254-PA,GB_protein:AAF50503.1,REFSEQ:NP_648164,GB_protein:AAF50503; MD5=e85c436b5893a7fa2213f99e412e69f2; length=525; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] Extra-extra OS=Drosophila melanogaster GN=exex PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=3L:join(7941466..7942385,7943251..7943521,7943657..7944043); ID=FBpp0076468; name=exex-PA; parent=FBgn0041156,FBtr0076751; dbxref=FlyBase:FBpp0076468,FlyBase_Annotation_IDs:CG8254-PA,GB_protein:AAF50503.1,REFSEQ:NP_648164,GB_protein:AAF50503,FlyMine:FBpp0076468,modMine:FBpp0076468; MD5=e85c436b5893a7fa2213f99e412e69f2; length=525; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=3L:join(7948366..7949285,7950151..7950421,7950557..7950943); ID=FBpp0076468; name=exex-PA; parent=FBgn0041156,FBtr0076751; dbxref=FlyBase:FBpp0076468,FlyBase_Annotation_IDs:CG8254-PA,GB_protein:AAF50503.1,REFSEQ:NP_648164,GB_protein:AAF50503,FlyMine:FBpp0076468,modMine:FBpp0076468; MD5=e85c436b5893a7fa2213f99e412e69f2; length=525; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=3L:join(7948366..7949285,7950151..7950421,7950557..7950943); ID=FBpp0076468; name=exex-PA; parent=FBgn0041156,FBtr0076751; dbxref=FlyBase:FBpp0076468,FlyBase_Annotation_IDs:CG8254-PA,GB_protein:AAF50503.1,REFSEQ:NP_648164,GB_protein:AAF50503,FlyMine:FBpp0076468,modMine:FBpp0076468; MD5=e85c436b5893a7fa2213f99e412e69f2; length=525; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] FBpp0076468 type=protein; loc=3L:join(7948366..7949285,7950151..7950421,7950557..7950943); ID=FBpp0076468; name=exex-PA; parent=FBgn0041156,FBtr0076751; dbxref=FlyBase:FBpp0076468,FlyBase_Annotation_IDs:CG8254-PA,GB_protein:AAF50503.1,REFSEQ:NP_648164,GB_protein:AAF50503,FlyMine:FBpp0076468,modMine:FBpp0076468; MD5=e85c436b5893a7fa2213f99e412e69f2; length=525; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=3L:join(7948366..7949285,7950151..7950421,7950557..7950943); ID=FBpp0076468; name=exex-PA; parent=FBgn0041156,FBtr0076751; dbxref=FlyBase:FBpp0076468,FlyBase_Annotation_IDs:CG8254-PA,GB_protein:AAF50503.1,REFSEQ:NP_648164,GB_protein:AAF50503,UniProt/TrEMBL:Q9VSC2,FlyMine:FBpp0076468,modMine:FBpp0076468; MD5=e85c436b5893a7fa2213f99e412e69f2; length=525; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	525 amino acids
Gene Ontology:
Cellular Component:	nucleus [ISS]
Biological Process:	central nervous system development [IMP] nervous system development [TAS] regulation of transcription, DNA-dependent [IEA] regulation of transcription [IEA][ISS] axon target recognition [IMP]
Molecular Function:	transcription factor activity [ISS] sequence-specific DNA binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSAQVSQQP PPPPLTASSS TSMPSQLLLS HIQHHSSSLH HQRSHQRSSP PAQDYDQGSN  60
   61 QSTLSPRSQI TPSPPAASPT HSAATTGSPV STYTPALSPG GAQDSSQTES GQSSQMPLLV 120
  121 APMPVGTGPP HSHPPPPHPR LYVEGFPPPH HVPHPHPALG TYPLPRLPLM LPANPPGVPS 180
  181 GAAAPPPVSP QPAANHLSHS GATMATTTLL PPAQSQPKKS FCIDALLAKS QHQSGEPQPI 240
  241 IVDDRLAALH YARDQAELNH AFVTASNAAA AAQAAASAAG GISEQEALQR IRDSREYDSP 300
  301 SPDGMSRSES PTSSHRSSPP ISPGCEDQQQ PHGALHPQHL SMRMSDFHDE FKKPIPPHSP 360
  361 IRPQDFPLYA GGHPYQLLAQ GGSAFHRPLD PSGKPIPIPM GHNFMPSQLQ FEFLARAGML 420
  421 HHRIPELAAY PHHAILGKTR RPRTAFTSQQ LLELEKQFKQ NKYLSRPKRF EVASGLMLSE 480
  481 TQVKIWFQNR RMKWKRSKKA QQEAKERAKA NQQQQQQQQT PSAAS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.84

Protein Overview: exex-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: