Protein Overview: Pole2-PA

General Information:
Name(s) found:	Pole2-PA / FBpp0076789 [FlyBase]
Description(s) found: Found 21 descriptions. SHOW ALL	The gene Pole2 is referred to in FlyBase by the symbol Dmel\Pole2 (CG10489, FBgn0035644). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:5888785..5890479. It has the cytological map location 64F4. Based on sequence similarity, it is predicted to have molecular function</span>: DNA-directed DNA polymerase activity. There is experimental evidence that it is involved in the biological process</span>: cellular response to DNA damage stimulus. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
Organism:	Drosophila melanogaster
Length:	525 amino acids
Gene Ontology:
Cellular Component:	epsilon DNA polymerase complex [ISS][NAS]
Biological Process:	DNA replication [IEA] DNA-dependent DNA replication [IEA][NAS] response to DNA damage stimulus [IMP]
Molecular Function:	DNA binding [IEA] DNA-directed DNA polymerase activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDVDLLPLRK RITNTFKLCG FLIRSENSSY LAEQLLPFDA AERDKWLTVI TENLQSQKLL  60
   61 TPHVERAALE KAINELNRVG LDEGETVFAL IDAFTVPRFR YNQRIKKFEL DTQPRQLLTA 120
  121 PRMKSDYMQQ RYAMLLQKTL RHDLFAPAVI QDGVGAEAQA KKFKLQFAEN LLATSAMKEA 180
  181 VVLGLLTQLK EGKFYVEDPT GCVQLDLTGA RFHAGFFCEG CFVLAEGNYN NGVLKVDGLG 240
  241 FPPAEPANSS RAFFGTANTW GGESAKLLKY SAGLQELERT NTETTIVFLS DVRLDLPVVM 300
  301 EKLRQLFVGY DSCPPQAIVL MGPFTASTRN HHELRHHLDA LGGLAAGCEQ LKKQTDLILV 360
  361 PSSEDPTAPN ILPRAPIPEC LAAGLLKAWP RTQLATNPCR LQYCTQQIVV CRLDLMAKFC 420
  421 RNTLHFPEDT SQIEQHFART IVCQGHLVPI HPIAMPVHWD YDPALWLYPL PDLIVMGDSC 480
  481 QSFSSSQHGC TVLNTGSFVK SKFAFKVYIP ATRTIEDSEI PDELE

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: Pole2-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: