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Protein Overview: FBpp0303155, sif-PB

General Information:
Name(s) found: FBpp0303155 [FlyBase]
sif-PB / FBpp0111620 [FlyBase]
Description(s) found:
Found 27 descriptions.
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  • type=protein; loc=3L:join(5661135..5661241,5661791..5661984,5662064..5662182,5666167..5666365,5666647..5666802,5666872..5667176,5667475..5667821,5667890..5668308,5669377..5669545,5669611..5669859,5669919..5670048,5697025..5697170,5698062..5698341,5699542..5699673,5709197..5709379,5710638..5710838,5713977..5714204,5715482..5715668,5719580..5719694,5721591..5721742,5724540..5724736,5727566..5727709,5728826..5729020,5729086..5729194,5731084..5731263,5731326..5731463,5731516..5731673,5731739..5732116,5732206..5732434,5732544..5732826,5733204..5733307,5739568..5739653); ID=FBpp0303155; name=sif-PI; parent=FBgn0085447,FBtr0330122; dbxref=FlyBase:FBpp0303155,FlyBase_Annotation_IDs:CG34418-PI,REFSEQ:NP_001097519,GB_protein:ABW08474; MD5=f85ac3c3a5b7320f8de490070c88770f; length=2072; release=r5.56; species=Dmel; [FlyBase]
  • The gene still life is referred to in FlyBase by the symbol Dmel\sif (CG34418, FBgn0085447). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:5660920..5741139. It has the cytological map location 64E1-64E5. Based on sequence similarity, it is predicted to have molecular function</span>: Rho guanyl-nucleotide exchange factor activity. There is experimental evidence that it is involved in the biological process</span>: regulation of axonogenesis. 18 alleles are reported. The phenotype of these alleles is annotated with: bouton. It has 8 annotated transcripts and 8 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 2072 amino acids

    Gene Ontology:
    Cellular Component: synapse [NAS]
    intracellular [IEA]
    Biological Process: regulation of Rho protein signal transduction [IEA]
    regulation of axonogenesis [IGI]
    regulation of synapse structure and activity [TAS]
    synaptic transmission [NAS]
    actin cytoskeleton organization [NAS]
    Molecular Function: protein binding [IEA]
    guanyl-nucleotide exchange factor activity [NAS]
    receptor signaling protein activity [IEA]
    Rho guanyl-nucleotide exchange factor activity [IEA][ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGNKLSCSCA PLMRKAYRYE DSPWQSSRRR DGHLLSSFRL WAEVFHVSAS GAGTVKWQQV  60
   61 SEDLVPVNIT CIQDSPECIF HITAYNSQVD KILDVRLVQP GTRIGQASEC FVYWKDPMTN 120
  121 DTWGLNFTSP IDAKQFRECC SPSFKFSRKA SSSYSLKLDP PGKGKVKAKR KPLSTPASPS 180
  181 RVRQEPQCTC MSAEQYARLR TDPRVRGSST LPRNVGSHRI TDVDGQQQVG SGKVVSAVSS 240
  241 TSLYDNVASG GPGTNQGADT LPRQMKGGQQ DRQDVANSGV NTNTPGVIVT GVGNVGSDMC 300
  301 GQNHVGSQVG NDDPAACQMD MDLSKSEGTQ AGGGLHQSVG TCTSSSKGTG TRNKDFGDDM 360
  361 TRDAHSHDMH QHNVINNNTR RKTKSTEDMN VDTSTLKRML KPMPSTESPV TSPEMGRRRY 420
  421 NYYNANAAQT LGHPPHMHQH GMAMGMGGGG GGGHHIMNNN TMGRASSQSS RFSGSRSSHE 480
  481 IGRGYPPRNL YLELERERSC IEGSPPSDNV MFDNQCYATT PSSSNGNSDQ DQSYGQQQSS 540
  541 GQHPQQQQGP PQRSSRHQHH HQQAPNVTPT PGSPTSRLLL EYEMHLRNTL AKGMDAESYS 600
  601 LHTFEALLSQ SMENLANAKS STLPLPPHRP LSTIRDKERD RDRDGYYSDR NELIRERERE 660
  661 RDRGYLSDHN SSFSNSRCAS CIGESARAQW FRHSDGWRSG SSTIGSGSGH GMMTQQIPGS 720
  721 GHKRSPWDSL PSLRQDSSLN DSGYKSARAD SLEQRAEFIR QDSLRSEYLS DRESRYGIVQ 780
  781 QASIESTDSR MCYLTSSEIS DDDRMSLTTA VSDEDDGESV MASPYKAKAT GTAASSFNCT 840
  841 GAVRKAGFLS VKKWLLRKKH QIELARKRGW KGYWVCLKGT TLLFYPCDSR EGRSVEAAPK 900
  901 HLIIVDGAIM QPIPEHPKRD YIFCLSTAFG DAYLFQAPCQ VELENWVNSI HSACAAAFAR 960
  961 HRGKTGTLHL LQEEIFRLEK AIESDHKLKH MAELQQSVVT DQETRHQIQT QILQWEENLE1020
 1021 RLHCEQFRLR CYMASLQSGE LPNPKSLLTH VSRPTKNTLN KLGVFTVSSF HAFICARSPS1080
 1081 LLNNLLAGRG ATKRRPPMLS RSNSGSSRRS MQMNSRDEPE KTFKVAMPDN AYSTVYLRDA1140
 1141 MSVEEFLASA CARRNLNPME HFVRVKKRRD MEDHNYFVPH RNDLIENYLH NHEFVEVCMK1200
 1201 ILYQVELQRT TLEQMWGFSV EAELIENAER QDELCCYVSR VEDKSVAMHN GIIKGDEIMV1260
 1261 INGAIVSDLD MMYLESVLQE EQSLSMMMRS SRTEPPDLVG IMRVTDDMID SLVCPPPPTD1320
 1321 PPVMSEEMIT GLIVPAPGWN GTSKDLYSPE AESSPATSFV DPAAMAAQLA VGGVGGVVVG1380
 1381 GLGVAKPTSR TSSFEIENLL KTAEQETRKS SPTGSVTSSV STTALTPSRQ LTDAEKLRKV1440
 1441 VMELVDTERT YVKHLNNLLE HYLEPMKRET FLSNAEINAL FGNIHEIVTF QRQFLQNLEE1500
 1501 SLDLEPDFNK FEHCGQFRNV LFAIGSAFLY YVNHFKLYSS FCASHSKAQK VLHPNEGNHA1560
 1561 LQEFLAARNP KQQHSSTLES YLIKPIQRIL KYPLLLQQMR NLTDTRADEH VHLCEALKGM1620
 1621 EKVAEHINEM QRIHEEYGAI FDHLFRQHQK SCKQPIDLSP GDLLYYGGVE WLNISDFLGK1680
 1681 IKKGLELHAM CFVFKSAVVF LCKERLRQKK KLMGVSSKNA TNEVEIIRYQ VLIPVTEVQV1740
 1741 RASSAKDMDS HFLWELIHLR SQLQRRSEKV YVLSNSTADF RNAFLKTIRQ IIRESVRNMS1800
 1801 IPMKNFGGSS GSVSGHSSQG MGSMGYPGNS QTLERPKQQI TIVHGSHTLG KPKKKSGSQR1860
 1861 HSAGNIDYDN LSGSQEADDL PPSVGVVHYA SGHTHGQQMQ PAGFRGRSKT VGDVTEITCS1920
 1921 SPEPHQQQQQ QQQQQQQLMQ QGHAHAHPHP HPHPREPPPP PIRQPHLHHH SSDIERIDPG1980
 1981 TKSEGEEDSQ QGTIRPKATL GRTPNHLTLS TTSTLSVGST GSQARLIQSS HPPASYQPVL2040
 2041 MKDLGSPVWK PRDMINLGTD PQSTTRKDDV KN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.72

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle