Protein Overview: Gen-PA

General Information:
Name(s) found:	Gen-PA / FBpp0076879 [FlyBase]
Description(s) found: Found 22 descriptions. SHOW ALL	The gene XPG-like endonuclease is referred to in FlyBase by the symbol Dmel\Gen (CG10670, FBgn0027914). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:5142945..5145447. It has the cytological map location 64C7. There is experimental evidence that it has the molecular function</span>: double-stranded DNA specific 3'-5' exodeoxyribonuclease activity; 5'-3' exodeoxyribonuclease activity; single-stranded DNA specific 3'-5' exodeoxyribonuclease activity; endodeoxyribonuclease activity. There is experimental evidence that it is involved in the biological process</span>: DNA catabolic process, endonucleolytic; DNA catabolic process, exonucleolytic. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
Organism:	Drosophila melanogaster
Length:	726 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA][ISS]
Biological Process:	base-excision repair [ISS] DNA catabolic process, exonucleolytic [IDA] DNA catabolic process, endonucleolytic [IDA]
Molecular Function:	flap endonuclease activity [ISS] endonuclease activity [ISS] double-stranded DNA specific 3'-5' exodeoxyribonuclease activity [IDA] single-stranded DNA specific 3'-5' exodeoxyribonuclease activity [IDA] endodeoxyribonuclease activity [IDA] 5'-3' exodeoxyribonuclease activity [IDA] damaged DNA binding [ISS] single-stranded DNA specific endodeoxyribonuclease activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGVKELWGVL TPHCERKPIN ELRGKKVAID LAGWVCESLN VVDYFVHPRH HLKNLFFRTC  60
   61 YLIWEQVTPV FVLEGVAPKL KSQVIAKRNE LQFRGVKPKN SPECTQSQPS KGDKGRSRFN 120
  121 HVLKQCETLL LSMGIQCVQG PGEAEAYCAF LNKHGLVDGV ISQDSDCFAY GAVRVYRNFS 180
  181 VSTQGAQAAA GGAVDIYDMR EITSRMDFGQ QKIIVMALLC GCDYCPDGIG GIGKDGVLKL 240
  241 FNKYKETEIL DRMRSWRGET DKYNALEIRV DDKSICSNCG HIGKTQSHTK SGCSVCRTHK 300
  301 GCDESLWKEQ RLSIKSELTL RRKALLSPDF PNEEIIAEFL SEPDTIPNLN LNWRQPNLVK 360
  361 FIKQIGHLLQ WPEIYCFQKF FPILTRWQVQ QSKQEKILIQ PHEIIKKRTV KGVPSLELRW 420
  421 HDPSGIFKGL IPDKQIAEYE AEHPKGIEEL YYTIEPLDML ETAYPDLVAA FLKSKEKPAK 480
  481 KTTRKKKTAS EEENKENEPN SKPKRVVRKI KAQPEENQPL LHQFLGRKKE GTPVKAPAPQ 540
  541 RQQCSTPITK FLPSDLESDC DAEEFDMSDI VKGIISNPNA KPALTNHDGH QLHYEPMAED 600
  601 LSLRLAQMSL GNVNESPKVE TKRDLSQVDQ LPQSKRFSLE DSFDLLVKGD LQKLARTPVE 660
  661 RFKMQHRISE KIPTPVKPLD NISYFFNQSS DNADVFEELM NSSLVPQDQE DNAEDEEEDD 720
  721 LVVISD

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.98

Protein Overview: Gen-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: