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Protein Overview: Gef64C-PA, FBpp0...

General Information:
Name(s) found: FBpp0304983 [FlyBase]
Gef64C-PA / FBpp0073201 [FlyBase]
Description(s) found:
Found 25 descriptions.
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  • type=protein; loc=3L:join(4764890..4767056,4789122..4792153,4792217..4792612,4793921..4794148,4795801..4795932); ID=FBpp0304983; name=RhoGEF64C-PB; parent=FBgn0035574,FBtr0332738; dbxref=REFSEQ:NP_001261425,GB_protein:AGB94120,FlyBase:FBpp0304983,FlyBase_Annotation_IDs:CG32239-PB; MD5=6ebe7ccaa8536260db60fb0b81325b57; length=1984; release=r5.56; species=Dmel; [FlyBase]
  • The gene Guanine nucleotide exchange factor GEF64C is referred to in FlyBase by the symbol Dmel\Gef64C (CG32239, FBgn0035574). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:4692784..4796249. It has the cytological map location 64B13-64B17. It is reported to have molecular function</span>: guanyl-nucleotide exchange factor activity. There is experimental evidence that it is involved in the biological process</span>: inter-male aggressive behavior; axon guidance; spiracle morphogenesis, open tracheal system. 30 alleles are reported. The phenotypes of these alleles are annotated with: commissure; ventral nerve cord commissure; longitudinal connective. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1984 amino acids

    Gene Ontology:
    Cellular Component: intracellular [IEA]
    Biological Process: regulation of Rho protein signal transduction [IEA]
    spiracle morphogenesis, open tracheal system [IGI]
    axon guidance [IMP]
    inter-male aggressive behavior [IMP]
    Molecular Function: guanyl-nucleotide exchange factor activity [NAS]
    Rho guanyl-nucleotide exchange factor activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYDKSKKSWS QRLKTLGSGD SVDKNASLAA VSGMQAMQQL QLHMQQQHQQ LQQHQQQLQQ  60
   61 QQQQQQQQQH MAHHGHPQML TAYQLPPVPA AEFLPSALSR SMKYAEPWIY GTVRGIPARP 120
  121 SYGYHPHAAA IFAATEGVPG TTALAVVICS CAEYLNGTKR DVKKASVCKK CKGSRLPLAT 180
  181 IGGTGGTVRL PAVSGSSSSR RPMAATMRVV SATKKSRPSI LDPQKDPYDL MRRTRLLSPE 240
  241 PSSKEADSKS RSRSETVANQ PRGRTRTRAP PPPAPIQKSP AVAVPTAVPD PTDCWLMEDN 300
  301 ESLLQSSGLA SRANSRRSIL RCHVNPYDLI SSENGKLHSN LRKPNDHFDV ADAQLNDDEL 360
  361 GERKSKGTSK FYSGNVAAIA GQRISLGDKS GDSSDPGDSY ERIIMVSGGE STASNGPRRP 420
  421 PRNKKADEPA EMPAAAGAAG AAGAAATSPP AAAVTAATAV KPKAVTLAKV EKIEKDNESA 480
  481 YTVLTVTPTS PAIKSILKRP TTLELPGVGM SPLPLPPVNN SGLVTPAGKS QFYIPTPTGT 540
  541 AATPTSSSTP MATSTPTPNA SITATTAAAG AAITPGSRKK VQFMVEDKII ATTATAATTD 600
  601 DSDASAVATK TNYEYYNRKR NAATATAAAA TAASAAAASP PTAATSTDQQ EATLFAADID 660
  661 DEHNFTTSGE AAPPFIKPDS LHYEDVLPGP QIFDSSESSA KLSLPADGSP HVTTSPVSVL 720
  721 PTGTSNGVGG AGLGPGPAGV SGEEAPATAA ATAAATQKTT AANRDYDDDD EHNDKDESHD 780
  781 NKPNDLAERE QDREGDKEQG RAGELGISRQ EKKDAGGKPA ASQKRAAQTT QSRNPIRRAH 840
  841 SERHLSTAPL AAHGHASSAC AAGRNCHSIP MTPPASGPQN VILNFKDTMA LRIKSNRSDS 900
  901 RDLFQRRPTE PPPPPPPKGA GKGLEPLPHE INKSPLSPQR TVVRVAPFKP QQQQVGGSGD 960
  961 GFTHEVHRLK ISHSEEDADL GVELRRRPNL FLSSPGEEDA APKKTSILIS GDDCYSTMNL1020
 1021 SANAAQPLYQ SSVVVNSHSA TSVCISVSSA EEQEQELNQL NTLRSQQMGM GIAIIPIRGA1080
 1081 SEVNLQRSVS CISSTSSSST SSSSSSSGRG RTLIRLDYDR ERKGSATSST PINTPPVISS1140
 1141 TPATPPPTDL PIENANPLVP HETELLKILR NPVEAVKLNL VPHVCGLRAP TRESGKSKKI1200
 1201 QEEEVSGTPV KDPGFIAKLL QDPMLGQVAE GLETETVAEL IENSLQRLQQ ARRGIDMSGT1260
 1261 KDHDDMNRLI SASLQRIRLE RQPATPGISA TKEEDRLSNR GSISSANSFA SAHNYELFDF1320
 1321 DGGAGGNESD CYQSCSSELT ASGILEEDSV SPIKDPETEL DAATRAKFYQ LLVDATLAEI1380
 1381 EHSTHMDQTL GTDSEHHYES IRHSGDPIYE EIHEVPPPLP LSAPPLNDAE LEKKAARSIF1440
 1441 EGASKYDILS YLVDAKERGL AREESFDYGN NPKIIEEEAA DTLSDLDKRQ AEERERDRDS1500
 1501 GQSSMSSLSP PPHNFICGGA GKSSGSDVER QDSGVGSETS KTSRSKYQAT PTVLHLCEDC1560
 1561 DGAVEMQVGD NGILYAPLVC RKCGKKRVER KEIITEIVET EEKYGRDLQI ILEEFCHPML1620
 1621 VAGLLTQEQL SAIFLNTEDL LENNQTLAER MRDALDMSLE QGDDDLLTVN IGRIFLDFTQ1680
 1681 MLHAFESYCV RQAGASLLLA NLEKEKELLR IFLKVSQMEN AVLRRMNLNS FLMVPVQRVT1740
 1741 KYPLLLARLY KVTPSHLEGR ELLKQAQEKI ELHLNHINQE AKDVPTKLWR RISSSSPNRR1800
 1801 ASCEIDMINI KLRKMAIDVL EWNHDEVRFA MEGRLLYTQP TDSNWKKART IKLTPVNALL1860
 1861 VTNGKPSANY RAEKAMSEKL NFPKHTGIRE ASLLLVKEKC GRYTLIREPL YLDRCVVCSE1920
 1921 ADWDDYFEVQ EISSKDTFIF KAEDGVRTKQ WYTQLQYHAQ GMGAWRKRRN ALANIMINGM1980
 1981 LARS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.85

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle