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Protein Overview: FBpp0305196, Gad...

General Information:
Name(s) found: FBpp0305196 [FlyBase]
Gad1-PC / FBpp0073133 [FlyBase]
Gad1-PA / FBpp0073132 [FlyBase]
Gad1-PB / FBpp0073131 [FlyBase]
Description(s) found:
Found 56 descriptions.
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  • type=protein; loc=3L:complement(4075365..4075538,4075596..4075940,4076799..4076877,4078750..4078817,4078926..4079494,4082403..4082639,4084730..4084790); ID=FBpp0305196; name=Gad1-PD; parent=FBgn0004516,FBtr0332980; dbxref=REFSEQ:NP_001261396,GB_protein:AGB94091,FlyBase:FBpp0305196,FlyBase_Annotation_IDs:CG14994-PD; MD5=67339bcbeb6f20c036f90e4eb3edba3d; length=510; release=r5.56; species=Dmel; [FlyBase]
  • The gene Glutamic acid decarboxylase 1 is referred to in FlyBase by the symbol Dmel\Gad1 (CG14994, FBgn0004516). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:4074069..4088744. It has the cytological map location 64A5. There is experimental evidence that it has the molecular function</span>: glutamate decarboxylase activity. There is experimental evidence that it is involved in the biological process</span>: synapse assembly; gamma-aminobutyric acid biosynthetic process; neuromuscular junction development; neurotransmitter receptor metabolic process; glutamate catabolic process; larval locomotory behavior. 18 alleles are reported. The phenotypes of these alleles are annotated with: bouton; neuromuscular junction. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
  • The gene Glutamic acid decarboxylase 1 is referred to in FlyBase by the symbol Dmel\Gad1 (CG14994, FBgn0004516). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:4074069..4088744. It has the cytological map location 64A5. There is experimental evidence that it has the molecular function</span>: glutamate decarboxylase activity. There is experimental evidence that it is involved in the biological process</span>: synapse assembly; gamma-aminobutyric acid biosynthetic process; neuromuscular junction development; neurotransmitter receptor metabolic process; glutamate catabolic process; larval locomotory behavior. 18 alleles are reported. The phenotypes of these alleles are annotated with: bouton; neuromuscular junction. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
  • The gene Glutamic acid decarboxylase 1 is referred to in FlyBase by the symbol Dmel\Gad1 (CG14994, FBgn0004516). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:4074069..4088744. It has the cytological map location 64A5. There is experimental evidence that it has the molecular function</span>: glutamate decarboxylase activity. There is experimental evidence that it is involved in the biological process</span>: synapse assembly; gamma-aminobutyric acid biosynthetic process; neuromuscular junction development; neurotransmitter receptor metabolic process; glutamate catabolic process; larval locomotory behavior. 18 alleles are reported. The phenotypes of these alleles are annotated with: bouton; neuromuscular junction. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 510 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: glutamate catabolic process [IMP][NAS]
    neuromuscular junction development [IMP]
    synapse assembly [IMP]
    larval locomotory behavior [IMP]
    neurotransmitter receptor metabolic process [IMP]
    neurotransmitter biosynthetic process [NAS]
    gamma-aminobutyric acid biosynthetic process [IMP][NAS]
    response to mechanical stimulus [IGI]
    Molecular Function: pyridoxal phosphate binding [IEA]
    glutamate decarboxylase activity [IDA][ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLNPNGYKL SERTGKLTAY DLMPTTVTAG PETREFLLKV IDVLLDFVKA TNDRNEKVLD  60
   61 FHHPEDMKRL LDLDVPDRAL PLQQLIEDCA TTLKYQVKTG HPHFFNQLSN GLDLISMAGE 120
  121 WLTATANTNM FTYEIAPVFI LMENVVLTKM REIIGWSGGD SILAPGGSIS NLYAFLAARH 180
  181 KMFPNYKEHG SVGLPGTLVM FTSDQCHYSI KSCAAVCGLG TDHCIVVPSD EHGKMITSEL 240
  241 ERLILERKAK GDIPFFVNAT AGTTVLGAFD DINTIADICQ KYNCWMHIDA AWGGGLLMSR 300
  301 KHRHPRFTGV ERADSVTWNP HKLMGALLQC STIHFKEDGL LISCNQMSAE YLFMTDKQYD 360
  361 ISYDTGDKVI QCGRHNDIFK LWLQWRAKGT EGFEQQQDRL MELVQYQLKR IREQSDRFHL 420
  421 ILEPECVNVS FWYVPKRLRG VPHDAKKEVE LGKICPIIKG RMMQKGTLMV GYQPDDRRPN 480
  481 FFRSIISSAA VNEADVDFML DEIHRLGDDL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle