Protein Overview: dib-PA

General Information:
Name(s) found:	dib-PA / FBpp0073061 [FlyBase]
Description(s) found: Found 23 descriptions. SHOW ALL	The gene disembodied is referred to in FlyBase by the symbol Dmel\dib (CG12028, FBgn0000449). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:4062304..4064302. It has the cytological map location 64A5. There is experimental evidence that it has the molecular function</span>: ecdysteroid 22-hydroxylase activity. There is experimental evidence that it is involved in the biological process</span>: central nervous system development; dorsal closure; ecdysone biosynthetic process; head involution; midgut development; chitin-based embryonic cuticle biosynthetic process. 23 alleles are reported. The phenotypes of these alleles are annotated with 20 unique terms, many of which group under: organ system; nervous system; anatomical structure; cuticle; embryonic nervous system; primordium; multi-cell-component structure; integumentary system; cuticular specialization; ectoderm derivative; cytoplasmic part; cephalopharyngeal skeleton; commissure; midgut constriction. It has one annotated transcript and one annotated polypeptide. [FlyBase]
Organism:	Drosophila melanogaster
Length:	489 amino acids
Gene Ontology:
Cellular Component:	mitochondrion [IDA][ISS][NAS] mitochondrial inner membrane [NAS]
Biological Process:	dorsal closure [IMP][TAS] central nervous system development [IMP] midgut development [IMP] chitin-based embryonic cuticle biosynthetic process [IMP] head involution [IMP] oxidation reduction [IEA] ecdysone biosynthetic process [IDA][IMP] ecdysone metabolic process [NAS]
Molecular Function:	ecdysteroid 22-hydroxylase activity [IDA] electron carrier activity [IEA][ISS][NAS] heme binding [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLTKLLKISC TSRQCTFAKP YQAIPGPRGP FGMGNLYNYL PGIGSYSWLR LHQAGQDKYE  60
   61 KYGAIVRETI VPGQDIVWLY DPKDIALLLN ERDCPQRRSH LALAQYRKSR PDVYKTTGLL 120
  121 PTNGPEWWRI RAQVQKELSA PKSVRNFVRQ VDGVTKEFIR FLQESRNGGA IDMLPKLTRL 180
  181 NLELTCLLTF GARLQSFTAQ EQDPRSRSTR LMDAAETTNS CILPTDQGLQ LWRFLETPSF 240
  241 RKLSQAQSYM ESVALELVEE NVRNGSVGSS LISAYVKNPE LDRSDVVGTA ADLLLAGIDT 300
  301 TSYASAFLLY HIARNPEVQQ KLHEEARRVL PSAKDELSMD ALRTDITYTR AVLKESLRLN 360
  361 PIAVGVGRIL NQDAIFSGYF VPKGTTVVTQ NMVACRLEQH FQDPLRFQPD RWLQHRSALN 420
  421 PYLVLPFGHG MRACIARRLA EQNMHILLLR LLREYELIWS GSDDEMGVKT LLINKPDAPV 480
  481 LIDLRLRRE

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.85

Protein Overview: dib-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: