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Protein Overview: eIF5B-PB, FBpp03...

General Information:
Name(s) found: FBpp0301573 [FlyBase]
FBpp0301570 [FlyBase]
eIF5B-PB / FBpp0073003 [FlyBase]
Description(s) found:
Found 31 descriptions.
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  • type=protein; loc=3L:complement(3428976..3429083,3432204..3432365,3443458..3443565,3445365..3445560,3447648..3447724,3457215..3457347,3457412..3458840,3458948..3460098,3460172..3460242); ID=FBpp0301573; name=eIF5B-PF; parent=FBgn0026259,FBtr0309839; dbxref=FlyBase:FBpp0301573,FlyBase_Annotation_IDs:CG10840-PF,REFSEQ:NP_001246602,GB_protein:AFH04273; MD5=922963336787642006ec558af599da06; length=1144; release=r5.56; species=Dmel; [FlyBase]
  • type=protein; loc=3L:complement(3428976..3429083,3432204..3432365,3443458..3443565,3445365..3445560,3447648..3447724,3457215..3457347,3457412..3458840,3458948..3460098,3460172..3460242); ID=FBpp0301570; name=eIF5B-PC; parent=FBgn0026259,FBtr0309836; dbxref=FlyBase:FBpp0301570,FlyBase_Annotation_IDs:CG10840-PC,REFSEQ:NP_001246599,GB_protein:AFH04270; MD5=922963336787642006ec558af599da06; length=1144; release=r5.56; species=Dmel; [FlyBase]
  • The gene eIF5B is referred to in FlyBase by the symbol Dmel\eIF5B (CG10840, FBgn0026259). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:3428654..3460602. It has the cytological map location 63E1. Based on sequence similarity, it is predicted to have molecular function</span>: translation initiation factor activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: translational initiation. 8 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1144 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [ISS]
    cytosol [ISS]
    Biological Process: translational initiation [ISS]
    Molecular Function: GTP binding [IEA]
    translation initiation factor activity [ISS]
    DEAD/H-box RNA helicase binding [TAS]
    GTPase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVKAKKGKKE ILTKVEGGSS VDEISDVDSD QLSLNNKQNH ALKGNQAGDD DVKAVTKGVK  60
   61 KLNVKGKGKA GKNDDSDEEE VVPAKGKASK KSAFELLMDD DEQDEPAAQE SQSEKEEKVV 120
  121 VSKPQKNEKK GKKAKRKGKD DDDEDLDKVL AELQAEYAGE AAPAATTVVS PEELADEFSK 180
  181 KKKNKKQAKQ AAVAENAGED EASDDEEGGS TVKSAAQKKK EKKERQKREA ALAKQKAATE 240
  241 PKPKPVEKPA PEPEPVATEE VQPAAEEEEE KSSKNKKKGK KDKKAEPEEE KKDAKKKGMS 300
  301 ASMVAAMQEQ LRKRKEEEER LEREEAERIR LEDEREEARL EAVRLEAERK EKKKQREAER 360
  361 KARLKAEGKL LTKKQKEDRA RAQALLESLK AQGLEIPDPN DKRPTRPGTR IRPNKKKGPK 420
  421 EEAAEEEAKA AEAEAQSAAA AAAAAAAEKA EEERVKESWD ATDSEAEPEP EEETSQATNN 480
  481 GKTEAAEEEN EDTDDDEDDD DDEDDSDDSD GDSDDSREVS VLANDPESRR LRAEARILKR 540
  541 QAEAEKKRST DELRAGVVCV LGHVDTGKTK ILDKLRRTHV QDSEAGGITQ QIGATNVPIE 600
  601 AIKEQTKYVK AAAGFEHRLP GLLIIDTPGH ESFSNLRNRG SSLCDIAILV VDIMHGLEPQ 660
  661 TIESIQLLKK KKCPFIVALN KIDRLYDWKQ LARRDVRDVL KEQQSNTQLE FQQRTKDVIL 720
  721 QFAEQGLNAA LFYENTDPKT YISLVPTSAI SGEGMGNLLF MIADFCQNML AKRLMYSEEL 780
  781 QATVLEVKAL PGLGTTIDAI LINGKLREGQ TMVVAGTDGP IVTQIRSLLM PQPMKELRVK 840
  841 NAYVEYKEVK AAQGVKIAAK DLEKAIAGIN LLIAHKPDEV EICTEEVARE LKSALSHIKL 900
  901 AQTGVHVQAS TLGSLEALLE FLRTSKIPYS AIRIGPVVKR DVMKASTMLE HEAQYATILA 960
  961 FDVKIEREAQ EMADSLGVKI FQADIIYHLF DKFTAYREEL KQKKREEFRS VAVFPCKLRI1020
 1021 LPQFVFNSRD PIVMGVMVEN GIVKVGTPIC VPSKEFVDIG IVTSIESNHK QIEFARKGQE1080
 1081 ICVKIDPIPG ESPKMFGRHF EADDMLISKI SRQSIDACKD YFRDDLIKAD WALMVELKKL1140
 1141 FEIL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle