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Protein Overview: CG12018-PA

General Information:
Name(s) found: CG12018-PA / FBpp0072658 [FlyBase]
Description(s) found:
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  • gi|7292154|gb|AAF47566.1| CG12018 [Drosophila melanogaster] [NCBI NR]
  • gi|21358653|ref|NP_647659.1| CG12018 [Drosophila melanogaster] [NCBI NR]
  • gi|13431497|sp|Q9W088.1|DPOD2_DROME RecName: Full=DNA polymerase delta small subunit [NCBI NR]
  • DNA polymerase delta small subunit OS=Drosophila melanogaster GN=CG12018 PE=2 SV=1 [Swiss-Prot]
  • (Q9W088) DNA polymerase delta small subunit (EC 2.7.7.7) [Swiss-Prot]
  • This gene is referred to in FlyBase by the symbol Dmel\CG12018 (CG12018, FBgn0027903). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:1775633..1777024. It has the cytological map location 62B4. Based on sequence similarity, it is predicted to have molecular function</span>: DNA-directed DNA polymerase activity. There is experimental evidence that it is involved in the biological process</span>: cellular response to DNA damage stimulus; mitotic spindle organization. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG12018-PA translation from_gene[CG12018 BcDNA:HL03874 FBgn0027903] seq_release:3 mol_weight=48009 cds_boundaries:(3L:1,756,310..1,757,602[+]) aa_length:431 transcript_info:[CG12018-RA seq_release:3] gene_info:[gene symbol:BcDNA:HL03874 FBgn0027903 ge [hmr_yeast5_DM3-1_pombe.fasta]
  • (AE003472) BcDNA:HL03874 gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG12018-PA [Drosophila melanogaster]gi|21358653|ref|NP_647659.1| CG12018-PA [Drosophila melanogaster]gi|13431497|sp|Q9W088|DPD2_DROME DNA polymerase delta small subunit [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3L:1775681..1776976; ID=FBpp0072658; name=CG12018-PA; parent=FBgn0027903,FBtr0072775; dbxref=FlyBase:FBpp0072658,FlyBase_Annotation_IDs:CG12018-PA,GB_protein:AAF47566.1,REFSEQ:NP_647659,GB_protein:AAF47566; MD5=dcf190bb07819f5ad8c88e9f06 [fly-100309-contam.fasta]
  • CG12018-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • DNA polymerase delta small subunit [nr-271106-contam.fasta]
  • type=protein; loc=3L:1775681..1776976; ID=FBpp0072658; name=CG12018-PA; parent=FBgn0027903,FBtr0072775; dbxref=FlyBase:FBpp0072658,FlyBase_Annotation_IDs:CG12018-PA,GB_protein:AAF47566.1,REFSEQ:NP_647659,GB_protein:AAF47566; MD5=dcf190bb07819f5ad8c88e9f06524f5d; length=431; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3L:1775681..1776976; ID=FBpp0072658; name=CG12018-PA; parent=FBgn0027903,FBtr0072775; dbxref=FlyBase:FBpp0072658,FlyBase_Annotation_IDs:CG12018-PA,GB_protein:AAF47566.1,REFSEQ:NP_647659,GB_protein:AAF47566; MD5=dcf190bb07819f5ad8c88e9f06524f5d; length=431; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • type=protein; loc=3L:1775681..1776976; ID=FBpp0072658; name=CG12018-PA; parent=FBgn0027903,FBtr0072775; dbxref=FlyBase:FBpp0072658,FlyBase_Annotation_IDs:CG12018-PA,GB_protein:AAF47566.1,REFSEQ:NP_647659,GB_protein:AAF47566,FlyMine:FBpp0072658,modMine:FBpp0072658; MD5=dcf190bb07819f5ad8c88e9f06524f5d; length=431; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3L:1775681..1776976; ID=FBpp0072658; name=CG12018-PA; parent=FBgn0027903,FBtr0072775; dbxref=FlyBase:FBpp0072658,FlyBase_Annotation_IDs:CG12018-PA,GB_protein:AAF47566.1,REFSEQ:NP_647659,GB_protein:AAF47566,FlyMine:FBpp0072658,modMine:FBpp0072658; MD5=dcf190bb07819f5ad8c88e9f06524f5d; length=431; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3L:1775681..1776976; ID=FBpp0072658; name=CG12018-PA; parent=FBgn0027903,FBtr0072775; dbxref=FlyBase:FBpp0072658,FlyBase_Annotation_IDs:CG12018-PA,GB_protein:AAF47566.1,REFSEQ:NP_647659,GB_protein:AAF47566,FlyMine:FBpp0072658,modMine:FBpp0072658; MD5=dcf190bb07819f5ad8c88e9f06524f5d; length=431; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FBpp0072658 type=protein; loc=3L:1775681..1776976; ID=FBpp0072658; name=CG12018-PA; parent=FBgn0027903,FBtr0072775; dbxref=FlyBase:FBpp0072658,FlyBase_Annotation_IDs:CG12018-PA,GB_protein:AAF47566.1,REFSEQ:NP_647659,GB_protein:AAF47566,FlyMine:FBpp0072658,modMine:FBpp0072658; MD5=dcf190bb07819f5ad8c88e9f06524f5d; length=431; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3L:1775681..1776976; ID=FBpp0072658; name=CG12018-PA; parent=FBgn0027903,FBtr0072775; dbxref=FlyBase:FBpp0072658,FlyBase_Annotation_IDs:CG12018-PA,GB_protein:AAF47566.1,REFSEQ:NP_647659,GB_protein:AAF47566,UniProt/Swiss-Prot:Q9W088,FlyMine:FBpp0072658,modMine:FBpp0072658; MD5=dcf190bb07819f5ad8c88e9f06524f5d; length=431; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 431 amino acids

    Gene Ontology:
    Cellular Component: delta DNA polymerase complex [ISS][NAS]
    Biological Process: DNA replication [IEA][NAS]
    mitotic spindle organization [IMP]
    response to DNA damage stimulus [IMP]
    Molecular Function: DNA binding [IEA]
    DNA-directed DNA polymerase activity [ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTNRLETKYE NLSSIFRLKG HDYQKQFFHL YAHRLAEMTR LLTPLAQKKW GNKEPIKKLC  60
   61 ELRGEQDVHC ILIGTIFKHQ AHKPSILRDI SEENQLAPQP PRQNYSDPED KIVLEDELQR 120
  121 VRLQGKLNGQ LLATGVVCAA LGGTDSDGFF NVEDILFYES GPQKPLAPIK RSRLLVLASG 180
  181 LDQLQAHKFV EALNLFQYWL AGSLGNNKEA GSMVRLIVAG NSVRASAMAH VPTLQVARTQ 240
  241 ANANDTVQAV SQLDQWFASW ARSLPVDIMP GPYDPANFML PQQPFHKCMF PQAAQLATFQ 300
  301 AVTNPYSCRL DEALVVGTSG QNVSDLLRST SLDSALEALR CTLTWGHVAP TAPDTLACYP 360
  361 YIESDPFILR ECPHVYYAGN CESFATELHE GSEGKRTRLV CVPSFSKTQS VAVVDLDTLD 420
  421 CRMVNFSVDA E

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle