Protein Overview: ru-PA

General Information:
Name(s) found:	ru-PA / FBpp0072574 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|23092766\|gb\|AAF47490.2\| roughoid [Drosophila melanogaster] [NCBI NR] gi\|21430358\|gb\|AAM50857.1\| LP02893p [Drosophila melanogaster] [NCBI NR] gi\|17864410\|ref\|NP_524790.1\| roughoid [Drosophila melanogaster] [NCBI NR] gi\|12744730\|gb\|AAK06753.1\|AF318284_1 roughoid/rhomboid-3 [Drosophila melanogaster] [NCBI NR] The gene roughoid is referred to in FlyBase by the symbol Dmel\ru (CG1214, FBgn0003295). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:1370620..1387435. It has the cytological map location 61F8. It is reported to have molecular function</span>: serine-type peptidase activity. There is experimental evidence that it is involved in the biological process</span>: compound eye photoreceptor fate commitment; compound eye cone cell fate commitment; epithelial cell migration, open tracheal system. 17 alleles are reported. The phenotypes of these alleles are annotated with: photoreceptor; eye; egg; cone cell; eye photoreceptor cell; wing; ommatidium; embryonic/larval ganglionic branch; pigment cell. It has one annotated transcript and one annotated polypeptide. [FlyBase] >CG1214-PA translation from_gene[CG1214 ru FBgn0003295] seq_release:3 mol_weight=36951 cds_boundaries:(3L:1,365,146..1,367,611[+]) aa_length:341 transcript_info:[CG1214-RA seq_release:3] gene_info:[gene symbol:ru FBgn0003295 gene_boundaries:(3L:1,351,2 [hmr_yeast5_DM3-1_pombe.fasta] (Q9W0F8) CG1214 protein (Roughoid/rhomboid-3) (LP02893p) [DrosMelano7227.FASTAC.txt] CG1214-PA [Drosophila melanogaster]gi\|21430358\|gb\|AAM50857.1\| LP02893p [Drosophila melanogaster]gi\|17864410\|ref\|NP_524790.1\| CG1214-PA [Drosophila melanogaster]gi\|12744730\|gb\|AAK06753.1\| roughoid/rhomboid-3 [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=3L:join(1384517..1384840,1386212..1386596,1386669..1386985); ID=FBpp0072574; name=ru-PA; parent=FBgn0003295,FBtr0072681; dbxref=FlyBase:FBpp0072574,FlyBase_Annotation_IDs:CG1214-PA,GB_protein:AAF47490.2,REFSEQ:NP_524790,GB_protein:AAF474 [fly-100309-contam.fasta] roughoid/rhomboid-3 [Drosophila melanogaster] [nr-271106-contam.fasta] LP02893p [Drosophila melanogaster] [nr-271106-contam.fasta] roughoid CG1214-PA [Drosophila melanogaster] [nr-271106-contam.fasta] CG1214-PA [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=3L:join(1384517..1384840,1386212..1386596,1386669..1386985); ID=FBpp0072574; name=ru-PA; parent=FBgn0003295,FBtr0072681; dbxref=FlyBase:FBpp0072574,FlyBase_Annotation_IDs:CG1214-PA,GB_protein:AAF47490.2,REFSEQ:NP_524790,GB_protein:AAF47490; MD5=27dc37ffd472351502c4d1ec8411ef68; length=341; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=3L:join(1384517..1384840,1386212..1386596,1386669..1386985); ID=FBpp0072574; name=ru-PA; parent=FBgn0003295,FBtr0072681; dbxref=FlyBase:FBpp0072574,FlyBase_Annotation_IDs:CG1214-PA,GB_protein:AAF47490.2,REFSEQ:NP_524790,GB_protein:AAF47490; MD5=27dc37ffd472351502c4d1ec8411ef68; length=341; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] LP02893p OS=Drosophila melanogaster GN=ru PE=2 SV=2 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=3L:join(1384517..1384840,1386212..1386596,1386669..1386985); ID=FBpp0072574; name=ru-PA; parent=FBgn0003295,FBtr0072681; dbxref=FlyBase:FBpp0072574,FlyBase_Annotation_IDs:CG1214-PA,GB_protein:AAF47490.2,REFSEQ:NP_524790,GB_protein:AAF47490,FlyMine:FBpp0072574,modMine:FBpp0072574; MD5=27dc37ffd472351502c4d1ec8411ef68; length=341; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=3L:join(1384517..1384840,1386212..1386596,1386669..1386985); ID=FBpp0072574; name=ru-PA; parent=FBgn0003295,FBtr0072681; dbxref=FlyBase:FBpp0072574,FlyBase_Annotation_IDs:CG1214-PA,GB_protein:AAF47490.2,REFSEQ:NP_524790,GB_protein:AAF47490,FlyMine:FBpp0072574,modMine:FBpp0072574; MD5=27dc37ffd472351502c4d1ec8411ef68; length=341; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=3L:join(1384517..1384840,1386212..1386596,1386669..1386985); ID=FBpp0072574; name=ru-PA; parent=FBgn0003295,FBtr0072681; dbxref=FlyBase:FBpp0072574,FlyBase_Annotation_IDs:CG1214-PA,GB_protein:AAF47490.2,REFSEQ:NP_524790,GB_protein:AAF47490,FlyMine:FBpp0072574,modMine:FBpp0072574; MD5=27dc37ffd472351502c4d1ec8411ef68; length=341; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] Rhomboid-like protein OS=Drosophila melanogaster GN=ru PE=2 SV=2 [DROME.fasta.20160308] FBpp0072574 type=protein; loc=3L:join(1384517..1384840,1386212..1386596,1386669..1386985); ID=FBpp0072574; name=ru-PA; parent=FBgn0003295,FBtr0072681; dbxref=FlyBase:FBpp0072574,FlyBase_Annotation_IDs:CG1214-PA,GB_protein:AAF47490.2,REFSEQ:NP_524790,GB_protein:AAF47490,FlyMine:FBpp0072574,modMine:FBpp0072574; MD5=27dc37ffd472351502c4d1ec8411ef68; length=341; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=3L:join(1384517..1384840,1386212..1386596,1386669..1386985); ID=FBpp0072574; name=ru-PA; parent=FBgn0003295,FBtr0072681; dbxref=FlyBase:FBpp0072574,FlyBase_Annotation_IDs:CG1214-PA,GB_protein:AAF47490.2,REFSEQ:NP_524790,GB_protein:AAF47490,UniProt/TrEMBL:Q9W0F8,FlyMine:FBpp0072574,modMine:FBpp0072574; MD5=27dc37ffd472351502c4d1ec8411ef68; length=341; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	341 amino acids
Gene Ontology:
Cellular Component:	integral to plasma membrane [ISS] integral to membrane [NAS] plasma membrane [NAS]
Biological Process:	compound eye photoreceptor fate commitment [IGI] epithelial cell migration, open tracheal system [IMP] signal transduction [IEA] epidermal growth factor receptor signaling pathway [NAS] compound eye cone cell fate commitment [IMP] leg disc proximal/distal pattern formation [TAS]
Molecular Function:	serine-type peptidase activity [NAS] serine-type endopeptidase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLLSGAPSQ GRRPKNRPLI GTVEEGEMPP STVLQMPPAP LSSKSGLVLG VCCDQLMAVQ  60
   61 PVQRASGAAA TKSNSPDWGN HRAKHHEGSA APFKWIPPFF IILATLLEVL VFLWVGADPP 120
  121 EDSLLVYRPD QRLQLWRFLS YALLHASWLH LGYNVLTQLL FGVPLELVHG SLRTGVIYMA 180
  181 GVLAGSLGTS VVDSEVFLVG ASGGVYALLA AQLASLLLNF GQMRHGVIQL MAVILFVFCD 240
  241 LGYALYSREL AMHQLQTRPS VSYIAHMTGA LAGISVGLLL LRQLDGGLRP RPLRWLALGV 300
  301 WCIFSAFGIA FNLVNTVTAQ LLAEEEGQVI RQHLMNDLGM G

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: ru-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: