Protein Overview: Ptpmeg-PA, Ptpme...

General Information:
Name(s) found:	Ptpmeg-PF / FBpp0291032 [FlyBase] Ptpmeg-PE / FBpp0291031 [FlyBase] Ptpmeg-PC / FBpp0072444 [FlyBase] Ptpmeg-PA / FBpp0072443 [FlyBase] Ptpmeg-PD / FBpp0072441 [FlyBase]
Description(s) found: Found 30 descriptions. SHOW ALL	The gene Ptpmeg is referred to in FlyBase by the symbol Dmel\Ptpmeg (CG1228, FBgn0035133). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:328099..356050. It has the cytological map location 61C1. Based on sequence similarity, it is predicted to have molecular function</span>: protein tyrosine phosphatase activity; cytoskeletal protein binding. There is experimental evidence that it is involved in the biological process</span>: axon extension involved in axon guidance; mushroom body development; autophagic cell death; salivary gland cell autophagic cell death; central complex development. 40 alleles are reported. The phenotypes of these alleles are annotated with: eye; mushroom body beta-lobe; mushroom body medial lobe; mushroom body vertical lobe; mushroom body alpha-lobe. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase] The gene Ptpmeg is referred to in FlyBase by the symbol Dmel\Ptpmeg (CG1228, FBgn0035133). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:328099..356050. It has the cytological map location 61C1. Based on sequence similarity, it is predicted to have molecular function</span>: protein tyrosine phosphatase activity; cytoskeletal protein binding. There is experimental evidence that it is involved in the biological process</span>: axon extension involved in axon guidance; mushroom body development; autophagic cell death; salivary gland cell autophagic cell death; central complex development. 40 alleles are reported. The phenotypes of these alleles are annotated with: eye; mushroom body beta-lobe; mushroom body medial lobe; mushroom body vertical lobe; mushroom body alpha-lobe. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase] The gene Ptpmeg is referred to in FlyBase by the symbol Dmel\Ptpmeg (CG1228, FBgn0035133). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:328099..356050. It has the cytological map location 61C1. Based on sequence similarity, it is predicted to have molecular function</span>: protein tyrosine phosphatase activity; cytoskeletal protein binding. There is experimental evidence that it is involved in the biological process</span>: axon extension involved in axon guidance; mushroom body development; autophagic cell death; salivary gland cell autophagic cell death; central complex development. 40 alleles are reported. The phenotypes of these alleles are annotated with: eye; mushroom body beta-lobe; mushroom body medial lobe; mushroom body vertical lobe; mushroom body alpha-lobe. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase] The gene Ptpmeg is referred to in FlyBase by the symbol Dmel\Ptpmeg (CG1228, FBgn0035133). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:328099..356050. It has the cytological map location 61C1. Based on sequence similarity, it is predicted to have molecular function</span>: protein tyrosine phosphatase activity; cytoskeletal protein binding. There is experimental evidence that it is involved in the biological process</span>: axon extension involved in axon guidance; mushroom body development; autophagic cell death; salivary gland cell autophagic cell death; central complex development. 40 alleles are reported. The phenotypes of these alleles are annotated with: eye; mushroom body beta-lobe; mushroom body medial lobe; mushroom body vertical lobe; mushroom body alpha-lobe. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase] The gene Ptpmeg is referred to in FlyBase by the symbol Dmel\Ptpmeg (CG1228, FBgn0035133). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3L:328099..356050. It has the cytological map location 61C1. Based on sequence similarity, it is predicted to have molecular function</span>: protein tyrosine phosphatase activity; cytoskeletal protein binding. There is experimental evidence that it is involved in the biological process</span>: axon extension involved in axon guidance; mushroom body development; autophagic cell death; salivary gland cell autophagic cell death; central complex development. 40 alleles are reported. The phenotypes of these alleles are annotated with: eye; mushroom body beta-lobe; mushroom body medial lobe; mushroom body vertical lobe; mushroom body alpha-lobe. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	952 amino acids
Gene Ontology:
Cellular Component:	cytoskeleton [IEA] cytoplasm [IEA] extrinsic to membrane [IEA]
Biological Process:	mushroom body development [IMP] autophagic cell death [IEP] central complex development [IMP] protein amino acid dephosphorylation [IEA][NAS] salivary gland cell autophagic cell death [IEP] axon extension involved in axon guidance [IMP]
Molecular Function:	protein tyrosine phosphatase activity [ISS][NAS] cytoskeletal protein binding [IEA][ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFERFRLNNL TRTFRLRGGG PELARDKKTP QRQQCVTVLF LDDITHTFRI EKRAKGSELL  60
   61 DQVFQYLELS ERDYFGLLFP QKPGDVVRWV DAQKQFKKQC SSVSLDNDAV PLLEFRVKFF 120
  121 VSDPSRLQEE FTRYQFYLQI KRNILLGKLP CSSNTQCLLA SYTVQSELGD FNALEHQPGY 180
  181 LSGMQLLCDQ TTEAERKVGE LHKLHRGQLP ADAEYNYLEH AKRLELYGID LHRATDSNGK 240
  241 ELQLGVSAVG LLVFQHSLRL RREPSENYDT LLGFGMSSHK HAKALWKSCV EHHSFFRLKR 300
  301 PHRLSRFLNI SLGSKFYYSG RTELQAVQES KQRGRIHKVF VRSPSKRLLG AAGGVGTSGS 360
  361 SGGTPMQQHS GSESANSHNN GKPAGAGTIL TITKTSRPHD NKVTSKEADS MPRKAWEQQS 420
  421 DEYDIQLDVG FIEQCTRRFE SASPSPMPPA YSSGQHSPIL LPTTIADAVG HQQPESGSDL 480
  481 ITIRLQADEQ GRYGFNVKGG VDLSLPVQVS KVVPHTPADR CTPRVCEGDE VLMINGRDVH 540
  541 GLRHEQVVAM IRDCRHQASG ELLLTVRPQR SAPLLLEEEP LYQYVPESDE IGSHSNLLDG 600
  601 DALFTQSLLL LSDGLASGAL LAQYELMYRK NPDLAITEAR KPANAPKNRY RDISPYDCTR 660
  661 VSLVNSLTGD YINANYVNME IPGGAVNRYI ATQGPLASTT TDFWRMVQQE SSHLLVMLTT 720
  721 VMESGRQKCH QYWPVTGEEL QLAEGFSVRC LSEKPDETGS FVFREFVLKD KHEQRHIHHM 780
  781 QYLAWPDHCV PSDPNLFLEF TERVRAARNR TLLQEIEESL KQVRLMDADA DADENGGLMR 840
  841 ERKCAASNGA TPEDETPVST SVHQCISAAN PPVIVHCSAG IGRTGVLILM DTALALMEAR 900
  901 EPVYPLDIVR TMRDQRACMV QNVSQYRFVC ECICAAYMKI SRSSAAINDD ED

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.94

Protein Overview: Ptpmeg-PA, Ptpme...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: