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Protein Overview: FBpp0310112, emp...

General Information:
Name(s) found: FBpp0310112 [FlyBase]
emp-PA / FBpp0072309 [FlyBase]
emp-PC / FBpp0072307 [FlyBase]
Description(s) found:
Found 40 descriptions.
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  • type=protein; loc=2R:complement(20864603..20864983,20865042..20865163,20865222..20865793,20865854..20866027,20866089..20866341,20867056..20867116); ID=FBpp0310112; name=emp-PD; parent=FBgn0010435,FBtr0343507; dbxref=FlyBase:FBpp0310112,FlyBase_Annotation_IDs:CG2727-PD; MD5=5a9166438e227fa3ff3b3c75e1dba02b; length=520; release=r5.56; species=Dmel; [FlyBase]
  • The gene epithelial membrane protein is referred to in FlyBase by the symbol Dmel\emp (CG2727, FBgn0010435). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:20864127..20872321. It has the cytological map location 60E11. Based on sequence similarity, it is predicted to have molecular function</span>: scavenger receptor activity. There is experimental evidence that it is involved in the biological process</span>: autophagic cell death; salivary gland cell autophagic cell death. 6 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
  • The gene epithelial membrane protein is referred to in FlyBase by the symbol Dmel\emp (CG2727, FBgn0010435). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:20864127..20872321. It has the cytological map location 60E11. Based on sequence similarity, it is predicted to have molecular function</span>: scavenger receptor activity. There is experimental evidence that it is involved in the biological process</span>: autophagic cell death; salivary gland cell autophagic cell death. 6 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 520 amino acids

    Gene Ontology:
    Cellular Component: integral to plasma membrane [ISS][NAS]
    plasma membrane [NAS]
    lysosome [IEA]
    Biological Process: autophagic cell death [IEP]
    salivary gland cell autophagic cell death [IEP]
    cell adhesion [IEA]
    defense response [NAS]
    Molecular Function: scavenger receptor activity [ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNGPKHKFCT KLSSTYLRKW WITIVVAAAL IIGGIVVACE FTVLIDAVVD RMVALRPGAK  60
   61 TFGWWAKPPV EPRISLYIYN VTNADDFLSN GSKAIVDEVG PYVYSETWEK VNIVENDNGT 120
  121 LSYNLRKIYS FREDLSVGPE DDVVIVPNIP MLSATSQSKH AARFLRLAMA SIMDILKIKP 180
  181 FVQVSVGQLL WGYEDPLLKL AKDVVPKEQK LPYEEFGLLY GKNGTSSDRV TVNTGVDDIR 240
  241 RYGIIDNFNG RTHLPHWTTD ACNTLAGTDG SIFPPHIDHD RILHVYDKDL CRLLPLVFEK 300
  301 EVMTSNEVPG YRFTPPEWVF ADVDSHPDNM CFCPAGKPSC SPNGLFNVSL CQYDSPIMLS 360
  361 FPHFYLADES LRTQVEGISP PMKEKHQFFF DVQPKMGTTL RVRARIQINL AVSQVFDIKQ 420
  421 VANFPDIIFP ILWFEEGIDN LPDEVTDLMR FAEQVPPKIR VALIVGLCAL GVILLLLSTF 480
  481 CLIRNSHRQS TLHLEGSNYL ATAQVDMNKK QNKDNQPARY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..66] MSA 1.114996 View MSA. No confident structure predictions are available.
    2 View Details [67..139] MSA 4.118981 View MSA. No confident structure predictions are available.
    3 View Details [140..292] MSA 4.137986 View MSA. No confident structure predictions are available.
    4 View Details [293..351] MSA 1.13299 View MSA. No confident structure predictions are available.
    5 View Details [352..520] MSA 6.131984 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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