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Protein Overview: CG16912-PA

General Information:
Name(s) found: CG16912-PA / FBpp0072334 [FlyBase]
Description(s) found:
Found 24 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG16912 (CG16912, FBgn0035064). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:20669244..20671018. It has the cytological map location 60E1. Based on sequence similarity, it is predicted to have molecular function</span>: tyrosine-tRNA ligase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: translation. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 464 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [ISS]
    Biological Process: tyrosyl-tRNA aminoacylation [IEA]
    translation [ISS]
    Molecular Function: tyrosine-tRNA ligase activity [ISS]
    ATP binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLPLRRSLLK PLQDVLRHSH RQMSQKNLLE LTDRGFFHGI FPDTAAPRMK QLFTRGQQSI  60
   61 YAGFDPTADS LHVGNLLVIM GLIHCQRAGH RPIALVGGAT GLIGDPSGRK TERNQLGETV 120
  121 IETNLKAIEQ QLRRVFENHE NCLWDSKKQK LPLAPLIIVN NADWYADLQL IDFVANMGRH 180
  181 FRMGSMLSRS SVQSRLESED GMSFTEFTYQ IFQAYDWLHL LRRHNCCFQM GGSDQTGNLM 240
  241 TGHELISRVE RKREVFGLTL PLVTTEEGDK FGKSAGNAVW LDGNKTSPFA LYQFFLRMPD 300
  301 SEVEKLLKLF TFIPLPQVEQ LMREHTKEPE KRKAQTLLAE DVTLLVHGES GLKQAERVTN 360
  361 ALYKGNVEGL AELNLSEIQQ TFQGATMVNL LTEPGMSILE LAMKAKCFPT ETDAVRIINA 420
  421 GGFYVNQKRV QNIAEVLTTG VHILRNGISL LRVGKRNFYI VRWQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..464] PSI-BLAST 114.0 STRUCTURE OF TYROSYL-T/RNA SYNTHETASE REFINED AT 2.3 ANGSTROMS RESOLUTION. INTERACTION OF THE ENZYME WITH THE TYROSYL ADENYLATE INTERMEDIATE

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ligase activity, forming carbon-oxygen bonds
    		•  7.16276509815667 bayes_pls_golite062009
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  7.16276509815667 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  7.13957775963187 bayes_pls_golite062009
  • tyrosine-tRNA ligase activity
    		•  6.18775771640881 bayes_pls_golite062009
  • ligase activity
    		•  6.11211476973434 bayes_pls_golite062009
  • glutamate-tRNA ligase activity
    		•  2.63681738794687 bayes_pls_golite062009
  • methionine-tRNA ligase activity
    		•  2.56893064485672 bayes_pls_golite062009
  • catalytic activity
    		•  2.37674226834122 bayes_pls_golite062009
  • arginine-tRNA ligase activity
    		•  1.50161401062914 bayes_pls_golite062009
  • tryptophan-tRNA ligase activity
    		•  1.14187887833901 bayes_pls_golite062009
  • cysteine-tRNA ligase activity
    		•  0.844943947059557 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.625793556381714 bayes_pls_golite062009
  • binding
    		•  0.485102284225571 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.449504767632354 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  0.2293846471193 bayes_pls_golite062009
  • glutamine-tRNA ligase activity
    		•  0.118292082006187 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle