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Protein Overview: uri-PA

General Information:
Name(s) found: uri-PA / FBpp0072215 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • The gene unconventional prefoldin RPB5 interactor is referred to in FlyBase by the symbol Dmel\uri (CG11416, FBgn0035025). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:20453082..20455605. It has the cytological map location 60D5. There is experimental evidence that it has the molecular function</span>: phosphatase inhibitor activity. There is experimental evidence that it is involved in the biological process</span>: spermatogenesis. 6 alleles are reported. The phenotypes of these alleles are annotated with: ovary; testis. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 731 amino acids

    Gene Ontology:
    Cellular Component: polytene chromosome [IDA]
    cytoplasm [IDA]
    prefoldin complex [IEA]
    Biological Process: spermatogenesis [IMP]
    protein folding [IEA]
    Molecular Function: phosphatase inhibitor activity [IDA]
    unfolded protein binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDRREDALLQ ALQTNASETE RWEAFKRDNE STIRNLDKFA KNLSVEVMVP IGRKALMPGE  60
   61 LIHTNELLVG HYEGYFSACS SHKAKEICQY RLKLAEEQLK KLAVENDLWQ KKLHTPFAEG 120
  121 AVPSGDQVEI VEDFNEESHN KWLAEHRKRM RQQKQKERLE REAEPVKKDN EVLRKLEERE 180
  181 MMEELGLDPD NIDEDQLHDM LNQEPLKSTN ESSPKSLTQE EEDELWKKLE AEEQNEADEL 240
  241 SSEAEESLKT TDNLVRQLMS GETETPSSKK RTAGTNRNVE IQDPISEDDG DDDDEGDQEE 300
  301 EVRTIREQMS LLPNEDREPF LRAQLHVLKA KMRKIQKVNF ISDELIHLMN VVVMLEDDLQ 360
  361 DLVFEQELEA SEEEEEVVEN NHLPDEPSKE LSTVSESSTN KRRISFALDD EKLEFRREET 420
  421 VAEMLPNAKK NSRDIIKLNA PLKPAGDPQP ASIKTKRQTT QDILQKVERN IEFVKENQSV 480
  481 QDFDLLNRIM EESTGLINTL HISFTHSGAI PSPSSDQSDG IPGKPSDFYV RYEKDRARPN 540
  541 DSFPIYVNGF EGEEHVKVPI MSEAARGSAY EDPRSQFSKP NSSEICFTHS GSITPTSNDQ 600
  601 SDDIPGNPFD FYEKYEKDRA KFSKSNSSEG DATDPESATK SILRNKSAVD LEPHNVNQQP 660
  661 KKGRKVRNQK KKERTLDDDL RDMSAYQKVM HDLVEKEPTA PEPLPPGKFI DSHAPKKRVS 720
  721 RFKEQRALNK T

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..100] FFAS03 4.2 Prefoldin alpha subunit
    2 View Details [101..466] PSI-BLAST 14.39794 Heavy meromyosin subfragment
    3 View Details [467..731] PSI-BLAST 3.522879 No description for 2dfsA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle