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Protein Overview: mAcR-60C-PB

General Information:
Name(s) found: mAcR-60C-PB / FBpp0072275 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • The gene muscarinic Acetylcholine Receptor 60C is referred to in FlyBase by the symbol Dmel\mAcR-60C (CG4356, FBgn0000037). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:20266159..20277235. It has the cytological map location 60C7. There is experimental evidence that it has the molecular function</span>: muscarinic acetylcholine receptor activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: muscarinic acetylcholine receptor signaling pathway. 6 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 805 amino acids

    Gene Ontology:
    Cellular Component: integral to plasma membrane [NAS]
    integral to membrane [IEA][ISS]
    plasma membrane [NAS]
    Biological Process: G-protein coupled receptor protein signaling pathway [IEA]
    muscarinic acetylcholine receptor signaling pathway [ISS]
    Molecular Function: muscarinic acetylcholine receptor activity [IDA][ISS]
    G-protein coupled amine receptor activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEPVMSLALA AHGPPSILEP LFKTVTTSTT TTTTTTTSTT TTTASPAGYS PGYPGTTLLT  60
   61 ALFENLTSTA ASGLYDPYSG MYGNQTNGTI GFETKGPRYS LASMVVMGFV AAILSTVTVA 120
  121 GNVMVMISFK IDKQLQTISN YFLFSLAIAD FAIGAISMPL FAVTTILGYW PLGPIVCDTW 180
  181 LALDYLASNA SVLNLLIISF DRYFSVTRPL TYRAKRTTNR AAVMIGAAWG ISLLLWPPWI 240
  241 YSWPYIEGKR TVPKDECYIQ FIETNQYITF GTALAAFYFP VTIMCFLYWR IWRETKKRQK 300
  301 DLPNLQAGKK DSSKRSNSSD ENTVVNHASG GLLAFAQVGG NDHDTWRRPR SESSPDAESV 360
  361 YMTNMVIDSG YHGMHSRKSS IKSTNTIKKS YTCFGSIKEW CIAWWHSGRE DSDDFAYEQE 420
  421 EPSDLGYATP VTIETPLQSS VSRCTSMNVM RDNYSMGGSV SGVRPPSILL SDVSPTPLPR 480
  481 PPLASISQLQ EMSAVTASTT ANVNTSGNGN GAINNNNNAS HNGNGAVNGN GAGNGSGIGL 540
  541 GTTGNATHRD SRTLPVINRI NSRSVSQDSV YTILIRLPSD GASSNAANGG GGGPGAGAAA 600
  601 SASLSMQGDC APSIKMIHED GPTTTAAAAP LASAAATRRP LPSRDSEFSL PLGRRMSHAQ 660
  661 HDARLLNAKV IPKQLGKAGG GAAGGGVGGA HALMNARNAA KKKKKSQEKR QESKAAKTLS 720
  721 AILLSFIITW TPYNILVLIK PLTTCSDCIP TELWDFFYAL CYINSTINPM CYALCNATFR 780
  781 RTYVRILTCK WHTRNREGMV RGVYN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..408] PSI-BLAST 54.045757 Rhodopsin
    2 View Details [409..636] PSI-BLAST 7.69897 No description for 1y0fB was found.
    3 View Details [637..805] FFAS03 5.52 Rhodopsin


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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