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Protein Overview: mAcR-60C-PA

General Information:
Name(s) found: mAcR-60C-PA / FBpp0072274 [FlyBase]
Description(s) found:
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  • gi|7291777|gb|AAF47197.1| muscarinic acetylcholine receptor 60C, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|24762610|ref|NP_726440.1| muscarinic acetylcholine receptor 60C, isoform A [Drosophila melanogaster] [NCBI NR]
  • The gene muscarinic Acetylcholine Receptor 60C is referred to in FlyBase by the symbol Dmel\mAcR-60C (CG4356, FBgn0000037). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:20266159..20277235. It has the cytological map location 60C7. There is experimental evidence that it has the molecular function</span>: muscarinic acetylcholine receptor activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: muscarinic acetylcholine receptor signaling pathway. 6 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • >CG4356-PA translation from_gene[CG4356 mAcR-60C FBgn0000037] seq_release:3 mol_weight=84793 cds_boundaries:(2R:19,424,338..19,428,447[-]) aa_length:788 transcript_info:[CG4356-RA seq_release:3] gene_info:[gene symbol:mAcR-60C FBgn0000037 gene_boundari [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9W180) MACR-60C protein [DrosMelano7227.FASTAC.txt]
  • (AE003464) mAcR-60C gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG4356-PA, isoform A [Drosophila melanogaster]gi|24762610|ref|NP_726440.1| CG4356-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2R:complement(20268290..20269379,20270764..20270900,20270959..20271142,20271447..20272402); ID=FBpp0072274; name=mAcR-60C-PA; parent=FBgn0000037,FBtr0072367; dbxref=FlyBase:FBpp0072274,FlyBase_Annotation_IDs:CG4356-PA,GB_protein:AAF47197 [fly-100309-contam.fasta]
  • muscarinic Acetylcholine Receptor 60C CG4356-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG4356-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=2R:complement(20268290..20269379,20270764..20270900,20270959..20271142,20271447..20272402); ID=FBpp0072274; name=mAcR-60C-PA; parent=FBgn0000037,FBtr0072367; dbxref=FlyBase:FBpp0072274,FlyBase_Annotation_IDs:CG4356-PA,GB_protein:AAF47197.1,REFSEQ:NP_726440,GB_protein:AAF47197; MD5=15c627417aa3abbbf359a927d54f88c4; length=788; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2R:complement(20268290..20269379,20270764..20270900,20270959..20271142,20271447..20272402); ID=FBpp0072274; name=mAcR-60C-PA; parent=FBgn0000037,FBtr0072367; dbxref=FlyBase:FBpp0072274,FlyBase_Annotation_IDs:CG4356-PA,GB_protein:AAF47197.1,REFSEQ:NP_726440,GB_protein:AAF47197; MD5=15c627417aa3abbbf359a927d54f88c4; length=788; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • Isoform A of Muscarinic acetylcholine receptor DM1 OS=Drosophila melanogaster GN=mAcR-60C [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=2R:complement(20268290..20269379,20270764..20270900,20270959..20271142,20271447..20272402); ID=FBpp0072274; name=mAcR-60C-PA; parent=FBgn0000037,FBtr0072367; dbxref=FlyBase:FBpp0072274,FlyBase_Annotation_IDs:CG4356-PA,GB_protein:AAF47197.1,REFSEQ:NP_726440,GB_protein:AAF47197,FlyMine:FBpp0072274,modMine:FBpp0072274; MD5=15c627417aa3abbbf359a927d54f88c4; length=788; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2R:complement(join(24383924..24384879,24383436..24383619,24383241..24383377,24380767..24381856)); ID=FBpp0072274; name=mAChR-A-PA; parent=FBgn0000037,FBtr0072367; dbxref=FlyBase:FBpp0072274,FlyBase_Annotation_IDs:CG4356-PA,GB_protein:AAF47197.1,REFSEQ:NP_726440,GB_protein:AAF47197,FlyMine:FBpp0072274,modMine:FBpp0072274; MD5=15c627417aa3abbbf359a927d54f88c4; length=788; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2R:complement(join(24383924..24384879,24383436..24383619,24383241..24383377,24380767..24381856)); ID=FBpp0072274; name=mAChR-A-PA; parent=FBgn0000037,FBtr0072367; dbxref=FlyBase:FBpp0072274,FlyBase_Annotation_IDs:CG4356-PA,GB_protein:AAF47197.1,REFSEQ:NP_726440,GB_protein:AAF47197,FlyMine:FBpp0072274,modMine:FBpp0072274; MD5=15c627417aa3abbbf359a927d54f88c4; length=788; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of P16395, Isoform A of Muscarinic acetylcholine receptor DM1 OS=Drosophila melanogaster GN=mAChR-A [DROME.fasta.20160308]
  • FBpp0072274 type=protein; loc=2R:complement(join(24383924..24384879,24383436..24383619,24383241..24383377,24380767..24381856)); ID=FBpp0072274; name=mAChR-A-PA; parent=FBgn0000037,FBtr0072367; dbxref=FlyBase:FBpp0072274,FlyBase_Annotation_IDs:CG4356-PA,GB_protein:AAF47197.1,REFSEQ:NP_726440,GB_protein:AAF47197,FlyMine:FBpp0072274,modMine:FBpp0072274; MD5=15c627417aa3abbbf359a927d54f88c4; length=788; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2R:complement(join(24383924..24384879,24383436..24383619,24383241..24383377,24380767..24381856)); ID=FBpp0072274; name=mAChR-A-PA; parent=FBgn0000037,FBtr0072367; dbxref=FlyBase:FBpp0072274,FlyBase_Annotation_IDs:CG4356-PA,GB_protein:AAF47197.1,REFSEQ:NP_726440,GB_protein:AAF47197,FlyMine:FBpp0072274,modMine:FBpp0072274; MD5=15c627417aa3abbbf359a927d54f88c4; length=788; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 788 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEPVMSLALA AHGPPSILEP LFKTVTTSTT TTTTTTTSTT TTTASPAGYS PGYPGTTLLT  60
   61 ALFENLTSTA ASGLYDPYSG MYGNQTNGTI GFETKGPRYS LASMVVMGFV AAILSTVTVA 120
  121 GNVMVMISFK IDKQLQTISN YFLFSLAIAD FAIGAISMPL FAVTTILGYW PLGPIVCDTW 180
  181 LALDYLASNA SVLNLLIISF DRYFSVTRPL TYRAKRTTNR AAVMIGAAWG ISLLLWPPWI 240
  241 YSWPYIEGKR TVPKDECYIQ FIETNQYITF GTALAAFYFP VTIMCFLYWR IWRETKKRQK 300
  301 DLPNLQAGKK DSSKRSNSSD ENTVVNHASG GLLAFAQVGG NDHDTWRRPR SESSPDAESV 360
  361 YMTNMVIDSG YHGMHSRKSS IKSTNTIKKS YTCFGSIKEW CIAWWHSGRE DSDDFAYEQE 420
  421 EPSDLGCTSM NVMRDNYSMG GSVSGVRPPS ILLSDVSPTP LPRPPLASIS QLQEMSAVTA 480
  481 STTANVNTSG NGNGAINNNN NASHNGNGAV NGNGAGNGSG IGLGTTGNAT HRDSRTLPVI 540
  541 NRINSRSVSQ DSVYTILIRL PSDGASSNAA NGGGGGPGAG AAASASLSMQ GDCAPSIKMI 600
  601 HEDGPTTTAA AAPLASAAAT RRPLPSRDSE FSLPLGRRMS HAQHDARLLN AKVIPKQLGK 660
  661 AGGGAAGGGV GGAHALMNAR NAAKKKKKSQ EKRQESKAAK TLSAILLSFI ITWTPYNILV 720
  721 LIKPLTTCSD CIPTELWDFF YALCYINSTI NPMCYALCNA TFRRTYVRIL TCKWHTRNRE 780
  781 GMVRGVYN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..393] PSI-BLAST 55.39794 Rhodopsin
    2 View Details [394..788] FFAS03 4.1 Rhodopsin


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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