YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: CG3376-PB

General Information:
Name(s) found: CG3376-PB / FBpp0072172 [FlyBase]
Description(s) found:
Found 19 descriptions.
SHOW ALL
  • This gene is referred to in FlyBase by the symbol Dmel\CG3376 (CG3376, FBgn0034997). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:20145552..20152746. It has the cytological map location 60C4. Based on sequence similarity, it is predicted to have molecular function</span>: sphingomyelin phosphodiesterase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: sphingomyelin catabolic process. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 708 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: sphingomyelin catabolic process [IEA]
    Molecular Function: sphingomyelin phosphodiesterase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTQQQPPWPS PISSSSSNPR GKCWLILVLM AVLPLVADVG ALPFLFTHIK PQINWTQPEM  60
   61 ESWVIEEQPR SIEPHLEPVL HPNRTHRALS SDSTDAEFLQ RLVSIRHNQT ASSRMLWYDV 120
  121 AGGDGLVYPP FVDKALKLLN LKQVAFEIEN SVMSKVTCTA CRAGAGMLQH QIQSGKTDAE 180
  181 LIRMITDYCT NLNIQSARVC QGVAQLFGSE LIYVLKRVNL SPDELCSFVI GDGCADVYNP 240
  241 YHEWEVIFPP VPKPPRLPDL PIPMEAAPFF KVLHISDTHY DPHYAEGSNA DCNEPLCCRL 300
  301 SSGRPATPNA AAGKWGDYRK CDTPKRTVDH MLSHIAETHK DIDYILWTGD LPPHDVWNQT 360
  361 KEENLAIIKD TVKQMVEMFP GVPIFPALGN HESAPVNSFP PPYVNQVDIS ISWLYDELDI 420
  421 QWRRWLPQSV THTVRRGAFY SVLVRPGFRI ISLNMNYCNN KNWWLLLNST DPATELQWFI 480
  481 YELQSAEFSN EKVHVIGHIP PGHSDCLKVW SRNFYKIISR YESTVTAQFY GHTHYDEFEM 540
  541 FYDPHDLNHP NGIAYIGPSV SPYYDLNPGY RIYYVDGDHD ATTRLVIDHE SWIMNLKEAN 600
  601 LYGYPIWYKL YTARAAYNMK ALRPSDWNNL LNELTNNQEL FELYYKYYWK NSPARPTCDA 660
  661 ECKKRLICDC RSGRSHDRKH FCAEVESKID EESSKSWKSW FYKGLTNS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..193] deduced N/A No confident structure predictions are available.
    2 View Details [194..708] PSI-BLAST 40.09691 Purple acid phosphatase, N-terminal domain; Plant purple acid phosphatase, catalytic domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • phosphoric ester hydrolase activity
    		•  3.1640402146807 bayes_pls_golite062009
  • hydrolase activity
    		•  2.06280293513737 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  1.62419884857008 bayes_pls_golite062009
  • catalytic activity
    		•  1.39852585255405 bayes_pls_golite062009
  • protein binding
    		•  1.33435965029646 bayes_pls_golite062009
  • binding
    		•  1.01605260539008 bayes_pls_golite062009
  • phosphatase activity
    		•  0.887417749186372 bayes_pls_golite062009
  • phosphoprotein phosphatase activity
    		•  0.744264552706022 bayes_pls_golite062009
  • protein serine/threonine phosphatase activity
    		•  0.707342350941796 bayes_pls_golite062009
  • signal transducer activity
    		•  0.683960217801108 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.683960217801108 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle