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Protein Overview: FBpp0310004, CG4...

General Information:
Name(s) found: FBpp0310004 [FlyBase]
CG4324-PA / FBpp0072106 [FlyBase]
Description(s) found:
Found 25 descriptions.
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  • type=protein; loc=2R:complement(19902496..19902781,19902844..19903238,19903291..19903362,19903425..19903550,19903609..19903672,19903733..19903857,19903913..19904169,19904227..19904338); ID=FBpp0310004; name=CG4324-PC; parent=FBgn0034956,FBtr0343347; dbxref=FlyBase:FBpp0310004,FlyBase_Annotation_IDs:CG4324-PC; MD5=12f16acb3a4531e0b81409a3e944b9e5; length=478; release=r5.56; species=Dmel; [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG4324 (CG4324, FBgn0034956). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:19902433..19904719. It has the cytological map location 60B2-60B3. Based on sequence similarity, it is predicted to have molecular function</span>: organic cation transmembrane transporter activity. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 478 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [IEA]
    Biological Process: transmembrane transport [IEA]
    Molecular Function: organic cation transmembrane transporter activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYYLNNEPAA LPSPANLAPR DVHSSTLELK TVSINPDDTY TVQQAINAFG FGWFHVKLSL  60
   61 LVGLCWMSDS MEMAILSILG PSLFCEWNVT KFQQASVTTV VFLGMMLSSS FWTQLSNRYG 120
  121 RKSALTLFGV LLVLYSILSS VAPSYAWLLT LRGLVGFAIG CVPQSVTLYA EFLPTKHKGK 180
  181 CVVLMDCFWA LGACFEVVLA LVVYPYYGWR GLLALSATPL LIFTILSPWL SESARYYSYN 240
  241 GHNDKAIKVL EQIAHNNKRH MLMGRLMADD EPSCAESFRS LLSPSLYRTT ILLWFLWLAS 300
  301 AFCYYGLVLV TTELLVARNK ESHPNECVTF MTSDFMDLLW ITLSEFPGIL LTIKVVKLFG 360
  361 KKKTIVLQYL ALVLCTLVLM SVESRFSTSV TLFIARGTIS GIFQAIYVYT PEIYPAALRS 420
  421 VGVSGCSVLA RLGAMLTPFV AQVLMDSSRI QAMSTYAIVG LLASIACVFL PRETVGYH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..478] PSI-BLAST 26.522879 Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transporter activity
    		•  4.09176719149278 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.5865018981083 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.3426261924492 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  3.29689809004391 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  1.94035843948137 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.59419818573076 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  1.5181741634556 bayes_pls_golite062009
  • secondary active transmembrane transporter activity
    		•  1.22264637452409 bayes_pls_golite062009
  • polyol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • alcohol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • glycerol transmembrane transporter activity
    		•  0.812001619402678 bayes_pls_golite062009
  • binding
    		•  0.805286077372817 bayes_pls_golite062009
  • symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • solute:cation symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • sugar:hydrogen symporter activity
    		•  0.143419068761182 bayes_pls_golite062009
  • cation:sugar symporter activity
    		•  0.143419068761182 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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