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Protein Overview: FBpp0297132, FBp...

General Information:
Name(s) found: FBpp0297132 [FlyBase]
FBpp0297131 [FlyBase]
Nap1-PA / FBpp0072128 [FlyBase]
Description(s) found:
Found 34 descriptions.
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  • type=protein; loc=2R:complement(19792837..19793064,19793128..19793316,19793379..19793519,19793583..19794051,19794138..19794223); ID=FBpp0297132; name=Nap1-PC; parent=FBgn0015268,FBtr0305990; dbxref=REFSEQ:NP_001246486,GB_protein:AFH08239,FlyBase_Annotation_IDs:CG5330-PC,FlyBase:FBpp0297132; MD5=000865d4f250b0cc3d2b7681c021638f; length=370; release=r5.56; species=Dmel; [FlyBase]
  • type=protein; loc=2R:complement(19792837..19793064,19793128..19793316,19793379..19793519,19793583..19794051,19794138..19794223); ID=FBpp0297131; name=Nap1-PB; parent=FBgn0015268,FBtr0305989; dbxref=REFSEQ:NP_001246485,GB_protein:AFH08238,FlyBase_Annotation_IDs:CG5330-PB,FlyBase:FBpp0297131; MD5=000865d4f250b0cc3d2b7681c021638f; length=370; release=r5.56; species=Dmel; [FlyBase]
  • The gene Nucleosome assembly protein 1 is referred to in FlyBase by the symbol Dmel\Nap1 (CG5330, FBgn0015268). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:19792696..19794837. It has the cytological map location 60A9. There is experimental evidence that it has the molecular function</span>: histone binding. There is experimental evidence that it is involved in the biological process</span>: regulation of transcription, DNA-dependent; nucleosome assembly. 24 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 370 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    cytoplasm [IDA]
    [NOT]ACF complex [IDA]
    Biological Process: regulation of transcription, DNA-dependent [IDA]
    nucleosome assembly [IDA][ISS][NAS]
    Molecular Function: histone binding [IDA][TAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDAPAEGHVD PESCNEIEDE KSGSDCQSMP AYMNSVMRRQ YLQQMVKMLP APVQNRIVFL  60
   61 KNLQLQHLNI EAQFFEDVYK LEQKYQVQYQ PLFDKRREII EGKVDPAEEK PQWKEPESST 120
  121 DNEADAEHFR EALSSLKSIP KDAKGIPGFW LTVFRNTAIM SEMVQPHDEP AIRKLIDISI 180
  181 KYDNGHSYTL EFHFDKNEYF SNSVLTKQYV LKSTVDPNDP FAFEGPEIYK CTGCTINWEK 240
  241 KMNLTVKTIR KKQKHKERGA VRTIVKQVPT DSFFNFFSPP EVPSDQEEVD DDSQQILATD 300
  301 FEIGHFLRAR IIPKAVLYYT GDIVDDEDDE DEEEYDENEE DEYDDDDAPP PKGPKSAGIK 360
  361 KQSPNDCPNQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..370] PSI-BLAST 62.69897 The structure of nucleosome assembly protein suggests a mechanism for histone binding and shuttling

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • histone binding
    		•  4.83364158381373 bayes_pls_golite062009
  • binding
    		•  2.67502047678266 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.19063722234765 bayes_pls_golite062009
  • DNA binding
    		•  2.02361409111178 bayes_pls_golite062009
  • protein binding
    		•  1.58681138679309 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.108342723404403 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle