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Protein Overview: bgcn-PA

General Information:
Name(s) found: bgcn-PA / FBpp0072141 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • The gene benign gonial cell neoplasm is referred to in FlyBase by the symbol Dmel\bgcn (CG30170, FBgn0004581). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:19740801..19746314. It has the cytological map location 60A4. There is experimental evidence that it has the molecular function</span>: translation repressor activity, nucleic acid binding. There is experimental evidence that it is involved in the biological process</span>: germ-line stem cell maintenance; oogenesis. 13 alleles are reported. The phenotypes of these alleles are annotated with: stem cell fusome; cystocyte; male germline stem cell; germline stem cell; fusome; germline cell; testis; gonad; female germline stem cell; germarium. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1215 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: germ cell development [TAS]
    cystoblast division [NAS][TAS]
    oogenesis [IMP]
    spermatogenesis [TAS]
    male meiosis [TAS]
    germ-line stem cell maintenance [IDA]
    spermatogonial cell division [TAS]
    fusome organization [TAS]
    Molecular Function: translation repressor activity, nucleic acid binding [IDA]
    helicase activity [IEA][ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNHIIQDKYI PQQLLYFLAG RRCCQQFPCT FRTSEHEAFA NNARSLGLRS QVVHVNGNSC  60
   61 VKVYKQACRH YLEEPKTLVL SSGATLNMFT LLSRKSLMGK EDLELYADLV SMKANASDLP 120
  121 SLHLPLPAIR PPNLRFWTEA QLNFLTAFLG HSLSDEILQS LYASRVIVYN AALCWDKSVF 180
  181 LPLVILDDCR NKKSNVKIMC IERQAILATY NSQRTANFFG EQLGETVGIQ LPYFSAVSSS 240
  241 TFIIYSTAQY FLRSLTSQQF RNISHLVVND VHLHDPYTDI LLSEIRMALS SHQNLRVVLL 300
  301 SQMGNPKKFT DFFGEGLQLN MIKQPEVAPR VSYLNELHSC IALAGIHKGP DIYKEIPEAF 360
  361 RANNPRNEQM DKCLQAYGEL GTDAALRPFL YAVNYDLAPV NYRHSLTGKT AVHFASELNK 420
  421 ANHLRLLLFM GADPYIVDLF QQNAISLAAM NGNHECIDVL NSYSLHGYVV KSAKPDFVDY 480
  481 DLIIDIMYLL RTKPEYSPGE YSPGNILIIL PTYYHIVKLN YMILSHCLTG SLQECSIFLL 540
  541 YDNMRNDYLQ ALVNASDETV KVVLATDIIE SLCLKVPFKY QIDTACRLNN VYDTTSCSGD 600
  601 DRFEWVAKDA LLRRELILQP NKGDVQCFRL ISKEAYEELS ETSQPSLQTM QLDKICLAVK 660
  661 LLSPNTIISE YLGITISPPP LINVHHAVQF LKKIDVLDDA EDVTWLGCRL MDIPVSCQLG 720
  721 RMLIFGILLR CLDPILTIVS SLSTADPLGI PFTEDIDNLW DRFTIYIQNS IKKERTYLSD 780
  781 NQFSDHFIFV RLYKEWQNRM HNRTPPLYLK DEYEFMLNGL MEQLTSIRSE IVSSLRAANL 840
  841 IHSRGKLSMN NLNQMSCNWH MVKAALTGGM YPNIYAVDTR KSSLKSAFSG NVSMHPNTVL 900
  901 RDFLEPLNIS AQSFRTPWIV CNRQKSHIVY ATLVVPLAVA MFSGHPRIRL SPICDSEMSL 960
  961 TDRNVNVFID EWIWMVMSKA TAEMVMRTRY YFFKMYHDLL KHCSELDMWR RDCEPVSQYT1020
 1021 VLTDTLSKIF ESEDGFVGFF KPPPITFLPT PQLPSLYLLS VNAHFSWARE VEENMLSKPH1080
 1081 HFNSHFIERQ FFVLYAGGDC EEFHSRNTPA FIESVLGKFV RPIDTPNRHI FVILYRKDPD1140
 1141 MMLSISRAKF VNGVFMLQEY FRNNIPVFEI LDACVSLNVQ TPVFDGRLMS ALIDKRVGNL1200
 1201 IMELFAFRHH WIHKR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..67] PSI-BLAST 5.69897 SmuBP-2
    2 View Details [68..149] deduced N/A No confident structure predictions are available.
    3 View Details [150..592] PSI-BLAST 11.0 No description for 2qeqA was found.
    4 View Details [593..642] PSI-BLAST 5.045757 No description for 2hjvA was found.
    5 View Details [643..888] FFAS03 0.97 No description for 2v8oA was found.
    6 View Details [889..969] MSA 2.598995 View MSA. No confident structure predictions are available.
    7 View Details [970..1215] MSA 1.272965 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  0.614651335571707 bayes_pls_golite062009
  • protein binding
    		•  0.0744329875422729 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.
    7 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.77

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle