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Protein Overview: stl-PA

General Information:
Name(s) found: stl-PA / FBpp0071796 [FlyBase]
Description(s) found:
Found 12 descriptions.
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  • The gene stall is referred to in FlyBase by the symbol Dmel\stl (CG3622, FBgn0086408). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:18696284..18703498. It has the cytological map location 59B2. Based on sequence similarity, it is predicted to have molecular function</span>: metalloendopeptidase activity. There is experimental evidence that it is involved in the biological process</span>: ovarian follicle cell stalk formation; oogenesis. 8 alleles are reported. The phenotypes of these alleles are annotated with: germline cyst; interfollicle cell; ovariole; ovary; oocyte; follicle cell; vitellarium; basal stalk; germarium. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 790 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: ovarian follicle cell stalk formation [IMP][TAS]
    oogenesis [IMP]
    proteolysis [IEA]
    Molecular Function: zinc ion binding [IEA]
    metalloendopeptidase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQKNFPTNTE SKVVSFLLAM INGVQLLYHH PTLGRRINFV LKRLEIWKSW DPPGLVRSRD  60
   61 VENYLNSFCK WQEKLNPFSD ADPLHYDHAL VLTGLDLVTY DKGKANSQVV GMATVKGMCT 120
  121 SIYSCTINEA KHFESVFVVA HEIGHNLGMR HDAKEISCDP TMHIMSPKLG SGKVTWSKCS 180
  181 RTYLEDFLMD PQAECLFDRD SFAGPWDHTA GGRLPGERFN ANQQCMLRFG KNFMQASTQS 240
  241 KMEICRDLHC RQDGLPWTSH PALEGTECGP NMWCRGGTCE ARSSKQGSYS ALKSWPPEHI 300
  301 PEATHEKIIR HEPNRIPPLL HDYNPMDNEL PGSPSNWGEW SEPSACESGC LYGQSRRLLE 360
  361 GSTGLRTLNR SCLNFPSRCI GRDRRFVTCN TPQCHKVPVQ TINDFATQVC MQARKSDPEL 420
  421 TGEGQQLPST LDASCKIFCR TRTNGTKSRR WTFPDGTTCK AKQHNPEDIT YCISGRCERF 480
  481 SCDNSTSNFF KMDSSFCEAR SVRPTRDSSD QESRQQTNRQ RYAERQEGKP QKNHYENEVA 540
  541 KRPSYGQGNH INAPASPYKR RNYHKPYPPE IPRPPPPASA SLIALDRSSS SESEWVAHPG 600
  601 CHSNCMTDSK GVQGVTSRLT GVESIQLCSY RIQPCERLQT AAEYAEQTCA RYRQKVRGLS 660
  661 GHGAQISASI DEPDRSCRVG CQDEFIKYRY YLVNGRNGHF PPGTRCSPVG KRYCVYGRCL 720
  721 EFGDDDLPLD KTHISLGQLR TRRKRSSISN DLFNITEIFI KPSHSDISAE NIEFTQPIHV 780
  781 SADELSSKSR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..417] PSI-BLAST 29.39794 No description for 2dw0A was found.
    2 View Details [418..496] PSI-BLAST 5.045757 Low density lipoprotein (LDL) receptor YWTD domain; Low density lipoprotein (LDL) receptor, different EGF domains; Ligand-binding domain of low-density lipoprotein receptor
    3 View Details [497..706] PSI-BLAST 4.69897 No description for 2dtgE was found.
    4 View Details [707..790] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • growth factor binding
    		•  4.48551849237988 bayes_pls_golite062009
  • insulin-like growth factor binding
    		•  3.58732804029568 bayes_pls_golite062009
  • insulin-like growth factor I binding
    		•  2.62174059145613 bayes_pls_golite062009
  • binding
    		•  2.00958032287792 bayes_pls_golite062009
  • protein binding
    		•  1.6400967625441 bayes_pls_golite062009
  • insulin-like growth factor II binding
    		•  0.48009413670884 bayes_pls_golite062009
  • catalytic activity
    		•  0.271811389148807 bayes_pls_golite062009
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.46

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle